Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

5.9%

1 terminated/withdrawn out of 17 trials

Success Rate

88.9%

+2.4% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

0%

0 of 8 completed trials have results

Key Signals

5 recruiting

Enrollment Performance

Analytics

Early Phase 1
4(57.1%)
N/A
3(42.9%)
7Total
Early Phase 1(4)
N/A(3)

Activity Timeline

Global Presence

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Clinical Trials (17)

Showing 17 of 17 trials
NCT02855476Recruiting

HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease

Role: collaborator

NCT06634628Early Phase 1Recruiting

iMagemHTT-009- FIH Evaluation of Novel Mutant Huntingtin PET Radioligand [11C]CHDI-00491009

Role: lead

NCT05360082Not ApplicableRecruiting

Comparison Between [11C]UCB-J and [18F]SynVest-1 PET in HD.

Role: collaborator

NCT03434548Recruiting

IMarkHD: in Vivo Longitudinal Imaging of HD Pathology

Role: collaborator

NCT01574053Recruiting

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

Role: lead

NCT03810898Early Phase 1Terminated

iMagemHTT: FIH Evaluation of Novel Mutant Huntingtin PET Radioligands [¹¹C]CHDI-00485180-R and [¹¹C]CHDI-00485626

Role: lead

NCT04406636Unknown

Natural History Study in Huntington Disease Gene Expansion Carriers (HDGECs) - SHIELD HD

Role: lead

NCT03628235Completed

HD-Charge: Indirect and Out-of-Pocket Costs of Huntington's Disease in the United States

Role: lead

NCT05224115Completed

Dosimetry of [11C]CHDI-180R and [11C]CHDI-626.

Role: collaborator

NCT02535884Not ApplicableCompleted

Deep Brain Stimulation (DBS) of the Globus Pallidus (GP) in Huntington's Disease (HD)

Role: collaborator

NCT04370470Unknown

Development of Assessments for Later Stage HD

Role: lead

NCT03344601Not ApplicableUnknown

PHysical Activity and Exercise Outcomes in Huntington's Disease

Role: collaborator

NCT03709173Completed

FuRST 2.0 Cognitive Pre-testing - Round 2

Role: lead

NCT02956148Early Phase 1Completed

Follow-up Measurement of Brain PDE10A Enzyme Levels in Huntington´s Disease Gene Expansion Carriers

Role: lead

NCT02881931Completed

FuRST 2.0 Cognitive Pre-Testing

Role: lead

NCT02061722Early Phase 1Completed

[PETDE10] Imaging of PDE10A Enzyme Levels in Huntington's Disease Gene Expansion Carriers and Healthy Controls With PET.

Role: lead

NCT01290861Completed

Cognitive Assessment Battery (CAB) Beta Study

Role: lead

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