Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 75/100

Failure Rate

17.4%

4 terminated/withdrawn out of 23 trials

Success Rate

81.8%

-4.7% vs industry average

Late-Stage Pipeline

9%

2 trials in Phase 3/4

Results Transparency

0%

0 of 18 completed trials have results

Key Signals

Enrollment Performance

Analytics

Phase 1
13(61.9%)
Phase 2
5(23.8%)
Phase 3
2(9.5%)
N/A
1(4.8%)
21Total
Phase 1(13)
Phase 2(5)
Phase 3(2)
N/A(1)

Activity Timeline

Global Presence

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Clinical Trials (23)

Showing 20 of 23 trials
NCT05809908Phase 3Not Yet Recruiting

Tricaprilin Phase 3 ALTER-AD (Alternative-Alzheimer Disease) Study

Role: lead

NCT04727970Phase 1Completed

Tricaprilin Infantile Spasms Pilot Study

Role: lead

NCT04437199Phase 2Completed

Tricaprilin Phase 2 Pilot Study in Migraine

Role: lead

NCT05628636Phase 1Completed

AC-OLE-01-VA Tolerability Study in Healthy Participants Under Different Dosing Conditions

Role: lead

NCT05408780Phase 1Completed

A Phase 1, Two-part, Randomized Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Liquid Formulation of Tricaprilin and Matching Placebo in Healthy Subjects

Role: lead

NCT05028114Phase 1Terminated

Tricaprilin Liquid Formulation PK Study

Role: lead

NCT04187547Phase 3Withdrawn

A Phase III Multi Regional Clinical Trial (MRCT) of Tricaprilin in Mild to Moderately Severe Probable Alzheimer's Disease With Optional Open Label Extension

Role: lead

NCT01741194Phase 2Completed

AC-1204 26-Week Long Term Efficacy Response Trial With Optional Open-label Ext

Role: lead

NCT00142805Phase 2Completed

Tricaprilin in Mild to Moderate Alzheimer's Disease

Role: lead

NCT00355550Phase 2Completed

Tricaprilin In Age-Associated Memory Impairment

Role: lead

NCT03971123Phase 1Completed

Study to Compare the Pharmacokinetics of Tricaprilin Formulations and a Placebo on Ketone Body Production

Role: lead

NCT04268953Phase 1Completed

Study to Compare the Pharmacokinetics of Daily Administration of Tricaprilin on Ketone Body Production

Role: lead

NCT03628352Phase 1Completed

Taste-masking Study for Tricaprilin in Sensory Panelists

Role: lead

NCT03551769Phase 1Completed

Pharmacokinetics of Tricaprilin Including Food Effect on Ketone Body Production

Role: lead

NCT03635879Phase 1Withdrawn

Medical Food Formulation Pharmacokinetic (PK) Study in Medium Chain Triglycerides

Role: lead

NCT01848327Not ApplicableCompleted

Caprylic Triglyceride for Treatment of Cognitive Impairments in Multiple Sclerosis

Role: collaborator

NCT03063645Phase 1Completed

Study to Compare the Pharmacokinetics of AC 1202 and Two Doses of AC-SD-01 on Ketone Body Production

Role: lead

NCT02959710Phase 1Completed

Evaluation of PK of AC-1204 Mixed in Water, AC-1202 Mixed in Water, and AC-1202 Mixed in Ensure® on Ketone Body Production

Role: lead

NCT02833012Phase 1Completed

Evaluation of PK of Caprylic Triglyceride Oil, AC-1202, AC-1204, and Axona on Ketone Body Production

Role: lead

NCT02747602Phase 1Completed

Evaluation of PK of AC1204 v Caprylic Triglyceride Oil Incl Food Effect on Ketone Body Production

Role: lead