Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 75/100

Failure Rate

19.0%

22 terminated/withdrawn out of 116 trials

Success Rate

69.4%

-17.1% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

46%

23 of 50 completed trials have results

Key Signals

14 recruiting23 with results13 terminated9 withdrawn

Enrollment Performance

Analytics

Phase 1
94(81.7%)
Phase 2
10(8.7%)
N/A
9(7.8%)
Early Phase 1
2(1.7%)
115Total
Phase 1(94)
Phase 2(10)
N/A(9)
Early Phase 1(2)

Activity Timeline

Global Presence

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Clinical Trials (116)

Showing 20 of 116 trials
NCT07211737Phase 1Recruiting

NKG2D.Zeta-NK Cell Conditioning With C7R.GD2.CAR-T Cells for Patients With Relapsed or Refractory Osteosarcoma or Neuroblastoma

Role: collaborator

NCT06176690Phase 1Recruiting

Constitutive IL7R (C7R) Modified Banked Allogeneic CD30.CAR EBVSTS for CD30-Positive Lymphomas

Role: collaborator

NCT00840853Phase 1Active Not Recruiting

Multi-virus CTLs Expressing CD19 Chimeric Receptors, CD19 Positive Malignancies Post SCT, MULTIPRAT

Role: collaborator

NCT03774654Phase 1Active Not Recruiting

CD19.CAR Allogeneic NKT for Patients With Relapsed or Refractory B-Cell Malignancies (ANCHOR)

Role: collaborator

NCT03635632Phase 1Active Not Recruiting

C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N)

Role: collaborator

NCT00710892Phase 1Active Not Recruiting

CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene

Role: collaborator

NCT01494103Phase 1Active Not Recruiting

Administration of Donor T Cells With the Caspase-9 Suicide Gene

Role: collaborator

NCT03690011Phase 1Active Not Recruiting

Cell Therapy for High Risk T-Cell Malignancies Using CD7-Specific CAR Expressed On Autologous T Cells

Role: collaborator

NCT01192555Phase 1Active Not Recruiting

Allogeneic Tumor Cell Vaccination With Oral Metronomic Cytoxan in Patients With High-Risk Neuroblastoma

Role: collaborator

NCT01333046Phase 1Active Not Recruiting

Administration of TAA-Specific CTLs; Hodgkin or Non-Hodgkin Lymphoma; TACTAL

Role: collaborator

NCT04099797Phase 1Recruiting

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

Role: collaborator

NCT01953900Phase 1Active Not Recruiting

iC9-GD2-CAR-VZV-CTLs/Refractory or Metastatic GD2-positive Sarcoma and Neuroblastoma

Role: collaborator

NCT02379520Phase 1Completed

HPV-16/18 E6/E7-Specific T Lymphocytes, Relapsed HPV-Associated Cancers, HESTIA

Role: collaborator

NCT03596086Phase 1Recruiting

HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM

Role: collaborator

NCT02287311Phase 1Active Not Recruiting

Most Closely Matched 3rd Party Rapidly Generated LMP, BARF1 And EBNA1 Specific CTL, EBV-Positive Lymphoma (MABEL)

Role: collaborator

NCT05103631Phase 1Active Not Recruiting

Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors

Role: collaborator

NCT06251544Phase 1Not Yet Recruiting

TRAIL-R2 and HER2 Bi-Specific Chimeric Antigen Receptor (CAR) T Cells for the Treatment of Metastatic Breast Cancer

Role: collaborator

NCT07297160Phase 1Not Yet Recruiting

CD70.CAR for CD70+ Lymphoma, Myeloma and Solid Tumors

Role: collaborator

NCT07197749Early Phase 1Not Yet Recruiting

Vitamin C With Steroids for Gastrointestinal GVHD

Role: collaborator

NCT01555892Phase 1Recruiting

Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE

Role: collaborator