Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 75/100

Failure Rate

19.8%

23 terminated/withdrawn out of 116 trials

Success Rate

69.3%

-17.3% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

44%

23 of 52 completed trials have results

Key Signals

14 recruiting23 with results13 terminated10 withdrawn

Enrollment Performance

Analytics

Phase 1
94(81.7%)
Phase 2
10(8.7%)
N/A
9(7.8%)
Early Phase 1
2(1.7%)
115Total
Phase 1(94)
Phase 2(10)
N/A(9)
Early Phase 1(2)

Activity Timeline

Global Presence

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Clinical Trials (116)

Showing 20 of 116 trials
NCT01192555Phase 1Active Not Recruiting

Allogeneic Tumor Cell Vaccination With Oral Metronomic Cytoxan in Patients With High-Risk Neuroblastoma

Role: collaborator

NCT06176690Phase 1Recruiting

Constitutive IL7R (C7R) Modified Banked Allogeneic CD30.CAR EBVSTS for CD30-Positive Lymphomas

Role: collaborator

NCT01853631Phase 1Recruiting

Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)

Role: collaborator

NCT03690011Phase 1Active Not Recruiting

Cell Therapy for High Risk T-Cell Malignancies Using CD7-Specific CAR Expressed On Autologous T Cells

Role: collaborator

NCT00881920Phase 1Active Not Recruiting

Kappa-CD28 T Lymphocytes, Chronic Lymphocytic Leukemia, B-cell Lymphoma or Multiple Myeloma, CHARKALL

Role: collaborator

NCT00586391Phase 1Active Not Recruiting

CD19 Chimeric Receptor Expressing T Lymphocytes In B-Cell Non Hodgkin's Lymphoma, ALL & CLL

Role: collaborator

NCT01494103Phase 1Active Not Recruiting

Administration of Donor T Cells With the Caspase-9 Suicide Gene

Role: collaborator

NCT02050347Phase 1Active Not Recruiting

Activated T Lymphocytes Expressing CARs, Relapsed CD19+ Malignancies Post-Allo HSCT(CARPASCIO)

Role: collaborator

NCT00840853Phase 1Active Not Recruiting

Multi-virus CTLs Expressing CD19 Chimeric Receptors, CD19 Positive Malignancies Post SCT, MULTIPRAT

Role: collaborator

NCT02379520Phase 1Completed

HPV-16/18 E6/E7-Specific T Lymphocytes, Relapsed HPV-Associated Cancers, HESTIA

Role: collaborator

NCT06815432Phase 1Recruiting

GPC-3 CAR T CELLS FOR Recurrent GPC-3 Positive Glioblastoma

Role: collaborator

NCT06251544Phase 1Recruiting

TRAIL-R2 and HER2 Bi-Specific Chimeric Antigen Receptor (CAR) T Cells for the Treatment of Metastatic Breast Cancer

Role: collaborator

NCT04219163Phase 1Active Not Recruiting

Chimeric Antigen Receptor T-cells for The Treatment of AML Expressing CLL-1 Antigen

Role: collaborator

NCT07297160Phase 1Withdrawn

CD70.CAR for CD70+ Lymphoma, Myeloma and Solid Tumors

Role: collaborator

NCT02442297Phase 1Active Not Recruiting

T Cells Expressing HER2-specific Chimeric Antigen Receptors(CAR) for Patients With HER2-Positive CNS Tumors

Role: collaborator

NCT07197749Early Phase 1Not Yet Recruiting

Vitamin C With Steroids for Gastrointestinal GVHD

Role: collaborator

NCT01333046Phase 1Completed

Administration of TAA-Specific CTLs; Hodgkin or Non-Hodgkin Lymphoma; TACTAL

Role: collaborator

NCT02494167Phase 1Completed

Administration of Donor Multi TAA-Specific T Cells for AML or MDS (ADSPAM)

Role: collaborator

NCT03081910Phase 1Recruiting

Autologous T-Cells Expressing a Second Generation CAR for Treatment of T-Cell Malignancies Expressing CD5 Antigen

Role: collaborator

NCT04715191Phase 1Recruiting

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

Role: collaborator