Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 75/100

Failure Rate

19.0%

22 terminated/withdrawn out of 116 trials

Success Rate

69.4%

-17.1% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

44%

22 of 50 completed trials have results

Key Signals

14 recruiting22 with results13 terminated9 withdrawn

Enrollment Performance

Analytics

Phase 1
94(81.7%)
Phase 2
10(8.7%)
N/A
9(7.8%)
Early Phase 1
2(1.7%)
115Total
Phase 1(94)
Phase 2(10)
N/A(9)
Early Phase 1(2)

Activity Timeline

Global Presence

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Clinical Trials (116)

Showing 20 of 116 trials
NCT04099797Phase 1Recruiting

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

Role: collaborator

NCT01953900Phase 1Active Not Recruiting

iC9-GD2-CAR-VZV-CTLs/Refractory or Metastatic GD2-positive Sarcoma and Neuroblastoma

Role: collaborator

NCT02379520Phase 1Completed

HPV-16/18 E6/E7-Specific T Lymphocytes, Relapsed HPV-Associated Cancers, HESTIA

Role: collaborator

NCT06176690Phase 1Recruiting

Constitutive IL7R (C7R) Modified Banked Allogeneic CD30.CAR EBVSTS for CD30-Positive Lymphomas

Role: collaborator

NCT03596086Phase 1Recruiting

HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM

Role: collaborator

NCT02287311Phase 1Active Not Recruiting

Most Closely Matched 3rd Party Rapidly Generated LMP, BARF1 And EBNA1 Specific CTL, EBV-Positive Lymphoma (MABEL)

Role: collaborator

NCT05103631Phase 1Active Not Recruiting

Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors

Role: collaborator

NCT07297160Phase 1Not Yet Recruiting

CD70.CAR for CD70+ Lymphoma, Myeloma and Solid Tumors

Role: collaborator

NCT06251544Phase 1Not Yet Recruiting

TRAIL-R2 and HER2 Bi-Specific Chimeric Antigen Receptor (CAR) T Cells for the Treatment of Metastatic Breast Cancer

Role: collaborator

NCT07197749Early Phase 1Not Yet Recruiting

Vitamin C With Steroids for Gastrointestinal GVHD

Role: collaborator

NCT01555892Phase 1Recruiting

Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE

Role: collaborator

NCT02291848Phase 1Recruiting

Tumor-Associated Antigen-Specific Cytotoxic T-Lymphocytes for Multiple Myeloma

Role: collaborator

NCT00586391Phase 1Active Not Recruiting

CD19 Chimeric Receptor Expressing T Lymphocytes In B-Cell Non Hodgkin's Lymphoma, ALL & CLL

Role: collaborator

NCT07211737Phase 1Not Yet Recruiting

NKG2D.Zeta-NK Cell Conditioning With C7R.GD2.CAR-T Cells for Patients With Relapsed or Refractory Osteosarcoma or Neuroblastoma

Role: collaborator

NCT01192464Phase 1Active Not Recruiting

EBV CTLs Expressing CD30 Chimeric Receptors For CD 30+ Lymphoma

Role: collaborator

NCT00709033Phase 1Completed

T-cells or EBV Specific CTLs, Advanced B-Cell NHL and CLL

Role: collaborator

NCT02065362Phase 1Active Not Recruiting

TGF-beta Resistant Cytotoxic T-lymphocytes in Treatment of EBV-positive Nasopharyngeal Carcinoma / RESIST-NPC

Role: collaborator

NCT06815432Phase 1Recruiting

GPC-3 CAR T CELLS FOR Recurrent GPC-3 Positive Glioblastoma

Role: collaborator

NCT00902044Phase 1Active Not Recruiting

Her2 Chimeric Antigen Receptor Expressing T Cells in Advanced Sarcoma

Role: collaborator

NCT04995003Phase 1Recruiting

HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma

Role: collaborator