Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 55/100

Failure Rate

23.2%

13 terminated/withdrawn out of 56 trials

Success Rate

74.5%

-12.0% vs industry average

Late-Stage Pipeline

21%

12 trials in Phase 3/4

Results Transparency

55%

21 of 38 completed trials have results

Key Signals

2 recruiting21 with results11 terminated

Enrollment Performance

Analytics

Phase 2
23(42.6%)
Phase 1
19(35.2%)
Phase 3
12(22.2%)
54Total
Phase 2(23)
Phase 1(19)
Phase 3(12)

Activity Timeline

Global Presence

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Clinical Trials (56)

Showing 20 of 56 trials
NCT06539507Phase 1Recruiting

A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BCX17725

Role: lead

NCT05453968Phase 3Active Not Recruiting

Berotralstat Treatment in Children With Hereditary Angioedema

Role: lead

NCT07228559Phase 1Recruiting

A Study of Avoralstat In Participants With Diabetic Macular Edema

Role: lead

NCT04933721Phase 3Enrolling By Invitation

Open-label Berotralstat Access to HAE Patients Previously Enrolled in Berotralstat Studies

Role: lead

NCT02303626Phase 2Completed

12-Week Safety and Efficacy Study of BCX4161 as an Oral Prophylaxis Against HAE Attacks

Role: lead

NCT05741346Phase 2Terminated

Long-term Safety of BCX9930 in Participants With Paroxysmal Nocturnal Hemoglobinuria

Role: lead

NCT04702568Phase 2Terminated

A Long-Term Safety Study of BCX9930 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Role: lead

NCT05116774Phase 2Terminated

BCX9930 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) in Participants With Inadequate Response to C5 Inhibitor Therapy

Role: lead

NCT06100900Phase 1Completed

Dose Escalation of BCX10013 in Participants with Paroxysmal Nocturnal Hemoglobinuria (PNH)

Role: lead

NCT05116787Phase 2Terminated

BCX9930 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) in Participants Not Receiving Other Complement Inhibitor Therapy

Role: lead

NCT03873116Phase 3Completed

Study to Evaluate the Efficacy and Safety of BCX7353 as an Oral Treatment for the Prevention of HAE Attacks in Japan

Role: lead

NCT05162066Phase 2Terminated

Study to Evaluate the Safety, Tolerability of BCX9930 in Participants With Either Complement 3 Glomerulopathy (C3G), Immunoglobulin A Nephropathy (IgAN), or Primary Membranous Nephropathy (PMN)

Role: lead

NCT03485911Phase 3Completed

Efficacy and Safety Study of BCX7353 as an Oral Treatment for the Prevention of Attacks in HAE

Role: lead

NCT03472040Phase 2Completed

A Long Term Safety Study of BCX7353 in Hereditary Angioedema

Role: lead

NCT04330534Phase 1Completed

First-in-Human Study of BCX9930 in Healthy Volunteers and Patients With PNH

Role: lead

NCT03800173Phase 1Completed

A Study to Evaluate the Single Dose Safety, Tolerability and Pharmacokinetics of IV BCX4430

Role: lead

NCT03891420Phase 1Terminated

A Study to Evaluate the Safety, Pharmacokinetics and Antiviral Effects of Galidesivir in Yellow Fever or COVID-19

Role: lead

NCT03240133Phase 2Completed

Study of BCX7353 as a Treatment for Attacks of Hereditary Angioedema

Role: lead

NCT02635724Phase 3Completed

Safety, PK and Effectiveness of IV Peramivir in Elderly and Higher Risk Subjects With Uncomplicated Influenza

Role: lead

NCT02369159Phase 3Completed

Safety, PK and Effectiveness of IV Peramivir Versus Oseltamivir in Pediatric Subjects With Uncomplicated Influenza

Role: lead