Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 15/100

Failure Rate

8.1%

3 terminated/withdrawn out of 37 trials

Success Rate

87.5%

+1.0% vs industry average

Late-Stage Pipeline

70%

26 trials in Phase 3/4

Results Transparency

57%

12 of 21 completed trials have results

Key Signals

8 recruiting12 with results

Enrollment Performance

Analytics

Phase 3
22(61.1%)
Phase 2
9(25.0%)
Phase 4
4(11.1%)
Phase 1
1(2.8%)
36Total
Phase 3(22)
Phase 2(9)
Phase 4(4)
Phase 1(1)

Activity Timeline

Global Presence

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Clinical Trials (37)

Showing 20 of 37 trials
NCT07523048Phase 2Recruiting

Dextromethorphan-Bupropion on Striatal Activity in Adults With Major Depressive Disorder

Role: collaborator

NCT07484217Phase 3Recruiting

Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

Role: lead

NCT06736509Phase 3Terminated

An Open-Label Study to Assess the Long-term Safety of AXS-05 in Subjects With Dementia of the Alzheimer's Type, ADVANCE-2 and ACCORD-2 Extension Study

Role: lead

NCT05972044Phase 3Completed

A Study to Assess the Efficacy and Safety of Solriamfetol in Subjects With ADHD (FOCUS)

Role: lead

NCT07398417Phase 3Recruiting

Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design

Role: lead

NCT04634669Phase 2Terminated

Open-Label Safety Study of AXS-05 in Subjects With TRD (EVOLVE)

Role: lead

NCT04163185Phase 3Completed

Initiating Early Control of Migraine Pain and Associated Symptoms

Role: lead

NCT04789174Phase 4Completed

Solriamfetol's Effect on Cognitive Health in Apnea Participants During a Randomized Placebo-controlled Study

Role: lead

NCT06360419Phase 3Completed

Progressing TAAR-1, Dopamine, and Norepinephrine in Depression Using Solriamfetol

Role: lead

NCT04947553Phase 3Completed

A Study to Assess the Long-term Safety and Efficacy of AXS-05 in Subjects With Alzheimer's Disease Agitation

Role: lead

NCT05550207Phase 3Completed

Open-Label Study of AXS-07 for the Acute Treatment of Migraine in Adults With a Prior Inadequate Response to an Oral CGRP Inhibitor (EMERGE)

Role: lead

NCT05557409Phase 3Completed

A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Alzheimer's Disease Agitation

Role: lead

NCT06568367Phase 3Recruiting

Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)

Role: lead

NCT06878976Phase 3Enrolling By Invitation

Open-Label Safety Study of Solriamfetol in Subjects With Binge Eating Disorder

Role: lead

NCT06413433Phase 3Recruiting

Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol

Role: lead

NCT05113745Phase 3Completed

A Study to Assess the Long-term Efficacy and Safety of AXS-12 (Reboxetine) in Subjects With Narcolepsy (ENCORE)

Role: lead

NCT04788953Phase 4Terminated

Clinical Trial of Solriamfetol for Excessive Sleepiness Related to Shift Work Disorder

Role: collaborator

NCT06170970Phase 2Recruiting

Solriamfetol for the Treatment of Multiple Sclerosis Fatigue

Role: collaborator

NCT05838430Phase 4Active Not Recruiting

Solriamfetol and CBT-I in Patients With Insomnia Disorder

Role: collaborator

NCT05059223Phase 3Completed

A Study to Assess the Efficacy and Safety of AXS-12 (Reboxetine) in Patients With Narcolepsy

Role: lead