Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

25.0%

3 terminated/withdrawn out of 12 trials

Success Rate

25.0%

-61.5% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

400%

4 of 1 completed trials have results

Key Signals

5 recruiting4 with results

Enrollment Performance

Analytics

Phase 1
8(72.7%)
Phase 2
3(27.3%)
11Total
Phase 1(8)
Phase 2(3)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT07400029Phase 2Recruiting

A Study of Obecabtagene Autoleucel in People With B-cell Acute Lymphoblastic Leukemia

Role: collaborator

NCT07053800Phase 2Recruiting

Obe-cel in Severe, Refractory Systemic Lupus Erythematosus With Active Lupus Nephritis

Role: lead

NCT04404660Phase 1Active Not Recruiting

A Study of CD19 Targeted CAR T Cell Therapy in Adult Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia (ALL)

Role: lead

NCT07139743Phase 1Recruiting

Obe-cel in Refractory Progressive Forms of Multiple Sclerosis

Role: lead

NCT03590574Phase 1Terminated

Phase I/II Study Evaluating AUTO4 in Patients With T Cell Receptor Beta Constant (TRBC)1 Positive T Cell Lymphoma

Role: lead

NCT06173518Phase 1Recruiting

A Study of CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL)

Role: lead

NCT06799221Unknown

Expanded Access Program for OOS Obe-cel

Role: lead

NCT06333483Phase 1Recruiting

Obe-cel in Adolescent [Applicable in UK Only] and Adult Severe, Refractory Systemic Lupus Erythematosus

Role: lead

NCT03628612Phase 2Enrolling By Invitation

Long-term Follow-up of Patients Treated With Genetically Modified Autologous T Cells

Role: lead

NCT03287817Phase 1Terminated

Cluster of Differentiation Antigen 19/22(CD19/22) CAR T Cells (AUTO3) for the Treatment of Diffuse Large B Cell Lymphoma

Role: lead

NCT03289455Phase 1Completed

CD19 /22 CAR T Cells (AUTO3) for the Treatment of B Cell Acute Lymphoblastic Leukemia (ALL)

Role: lead

NCT03287804Phase 1Terminated

APRIL CAR T Cells (AUTO2) Targeting BCMA and TACI for the Treatment of Multiple Myeloma

Role: lead

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