Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 70/100

Failure Rate

58.3%

7 terminated/withdrawn out of 12 trials

Success Rate

41.7%

-44.8% vs industry average

Late-Stage Pipeline

17%

2 trials in Phase 3/4

Results Transparency

160%

8 of 5 completed trials have results

Key Signals

8 with results

Enrollment Performance

Analytics

Phase 1
6(50.0%)
Phase 2
3(25.0%)
Phase 3
2(16.7%)
N/A
1(8.3%)
12Total
Phase 1(6)
Phase 2(3)
Phase 3(2)
N/A(1)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT04933968Phase 1Terminated

Study of ALVR106 in Patients With Respiratory Viral Infections After Hematopoietic Cell and Solid Organ Transplant

Role: lead

NCT04605484Phase 2Completed

Study of Posoleucel (Formerly Known as ALVR105; Viralym-M) in Kidney Transplant Patients With BK Viremia

Role: lead

NCT05305040Phase 2Terminated

Study of Posoleucel (ALVR105,Viralym-M) for Multi-Virus Prevention in Patients Post-Allogeneic Hematopoietic Cell Transplant

Role: lead

NCT04390113Phase 3Terminated

Study to Evaluate Viralym-M (ALVR105) for the Treatment of Virus-Associated Hemorrhagic Cystitis (HC)

Role: lead

NCT04693637Phase 2Completed

Posoleucel (ALVR105, Formerly Viralym-M) for Multi-Virus Prevention in Patients Post-Allogeneic Hematopoietic Cell Transplant

Role: lead

NCT05179057Phase 3Terminated

Posoleucel (ALVR105) for the Treatment of Adenovirus Infection in Pediatric and Adult Participants Receiving Standard of Care Following Allogeneic Hematopoietic Cell Transplantation

Role: lead

NCT04401410Phase 1Terminated

Anti-SARS Cov-2 T Cell Infusions for COVID 19

Role: collaborator

NCT02108522Not ApplicableCompleted

Multivirus-specific T Cells for the Treatment of Virus Infections After Stem Cell Transplant

Role: lead

NCT01570283Phase 1Completed

ARMS - Rapidly Generated Multivirus-Specific CTLs for Prophylaxis & Treatment of EBV, CMV, Adenovirus, HHV6 & BK Virus

Role: lead

NCT02313857Phase 1Completed

Most Closely Human Leukocyte Antigen (HLA)-Matched CMV-specific T Lymphocytes (Viralym-C)

Role: lead

NCT02276820Phase 1Withdrawn

Most Closely Human Leukocyte Antigen (HLA)-Matched Adenovirus-specific T Lymphocytes (Viralym-A)

Role: lead

NCT02313844Phase 1Withdrawn

Most Closely Human Leukocyte Antigen (HLA)-Matched BK Virus-specific T Lymphocytes (Viralym-B)

Role: lead

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