Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 75/100

Failure Rate

23.8%

15 terminated/withdrawn out of 63 trials

Success Rate

72.2%

-14.3% vs industry average

Late-Stage Pipeline

10%

6 trials in Phase 3/4

Results Transparency

5%

2 of 39 completed trials have results

Key Signals

4 recruiting2 with results13 terminated

Enrollment Performance

Analytics

Phase 2
46(80.7%)
Phase 1
5(8.8%)
Phase 3
5(8.8%)
Phase 4
1(1.8%)
57Total
Phase 2(46)
Phase 1(5)
Phase 3(5)
Phase 4(1)

Activity Timeline

Global Presence

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Clinical Trials (63)

Showing 20 of 63 trials
NCT05089916Phase 2Active Not Recruiting

Radiation During Osimertinib Treatment: a Safety and Efficacy Cohort Study

Role: lead

NCT07280377Phase 1Recruiting

A Study in Advanced or Metastatic Gastrointestinal Cancers Exploring Treatment Combinations With Pelareorep and Atezolizumab

Role: collaborator

NCT05212012Phase 1Active Not Recruiting

D,L-MEthadone and mFOLFOX6 in Treatment of Advanced Colorectal Cancer

Role: lead

NCT03044587Phase 2Completed

Nal-IRI With 5-fluorouracil (5-FU) and Leucovorin or Gemcitabine Plus Cisplatin in Advanced Biliary-tract Cancer

Role: lead

NCT05510895Phase 2Completed

Neoadjuvant Encorafenib, Binimetinib and Cetuximab for Patients With BRAF V600E Mutated/pMMR Localized Colorectal Cancer

Role: lead

NCT04221529Phase 2Completed

Patients With ES-SCLC and ECOG PS=2 Receiving Atezolizumab-Carboplatin-Etoposide

Role: lead

NCT05118724Phase 2Active Not Recruiting

Atezolizumab in Patients With MSI-h/MMR-D Stage II High Risk and Stage III Colorectal Cancer Ineligible for Oxaliplatin

Role: lead

NCT03468335Phase 3Completed

2nd-line Therapy With Nal-IRI After Gem/Nab-pac in Advanced Pancreatic Cancer - Predictive Role of 1st-line Therapy

Role: lead

NCT03197467Phase 2Completed

Neoadjuvant Anti PD-1 Immunotherapy in Resectable Non-small Cell Lung Cancer

Role: lead

NCT02622581Recruiting

Clinical Research Platform Into Molecular Testing, Treatment and Outcome of (Non-)Small Cell Lung Carcinoma Patients

Role: lead

NCT05701150Recruiting

AIO-BNHO Comprehensive Clinico-genomics Database Network - AIO-BNHO CONNECT

Role: lead

NCT03013946Phase 3Terminated

Role of PRoactivE Coaching on PAtient REported Outcome in Advanced or Metastatic RCC Treated With Sunitinib or a Combination of Pembrolizumab + Axitinib or Avelumab + Axitinib in First Line Therapy

Role: lead

NCT06380686Recruiting

Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome

Role: lead

NCT04046614Phase 1Completed

Feasibility and Safety of Nintedanib in Combination With Nivolumab in Pretreated Patients With Advanced or Metastatic NSCLC of Adenocarcinoma Histology

Role: lead

NCT03572582Phase 2Completed

Transarterial Chemoembolization in Combination With Nivolumab Performed for Intermediate Stage Hepatocellular Carcinoma

Role: lead

NCT01991873Phase 2Completed

Maintenance Therapy With 5-FU/FA Plus Panitumumab vs. 5-FU/FA Alone After Prior Induction and Re-induction After Progress for 1st-line Treatment of Metastatic Colorectal Cancer

Role: lead

NCT02047513Phase 2Completed

Neoadjuvant Plus Adjuvant or Only Adjuvant Nab- Paclitaxel Plus Gemcitabine for Resectable Pancreatic Cancer

Role: lead

NCT03473574Phase 2Completed

Durvalumab and Tremelimumab With Gemcitabine or Gemcitabine/Cisplatin Compared to Gemcitabine/Cisplatin in CCA Patients

Role: lead

NCT03317457Phase 2Completed

Durvalumab and Tremelimumab Compared to Doxorubicin in Patients With Advanced or Metastatic Soft Tissue Sarcoma

Role: lead

NCT03345810Phase 2Completed

Durvalumab (MEDI4736) in Frail and Elder Patients With Metastatic NSCLC (DURATION)

Role: lead