Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

6.7%

1 terminated/withdrawn out of 15 trials

Success Rate

92.9%

+6.4% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

0%

0 of 13 completed trials have results

Key Signals

Enrollment Performance

Analytics

Phase 2
8(53.3%)
Phase 1
7(46.7%)
15Total
Phase 2(8)
Phase 1(7)

Activity Timeline

Global Presence

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Clinical Trials (15)

Showing 15 of 15 trials
NCT04871594Phase 1Completed

Pre-operative Immunotherapy in Stage II-III Urothelial Cancer

Role: collaborator

NCT02953301Phase 2Completed

Resminostat for Maintenance Treatment of Patients With Advanced Stage Mycosis Fungoides (MF) or Sézary Syndrome (SS)

Role: lead

NCT04393753Phase 2Completed

Domatinostat in Combination With Avelumab in Patients With Advanced Merkel Cell Carcinoma Progressing on Anti-PD-(L)1

Role: lead

NCT04955340Phase 1Completed

A Phase 1, Open-label Study of the Absorption, Metabolism, Excretion of [14C]-Resminostat

Role: lead

NCT03278665Phase 1Completed

4SC-202 in Combination With Pembrolizumab in Patients Primary Refractory/Non-responding to Prior Anti-PD-1 Therapy

Role: lead

NCT04874831Phase 2Withdrawn

Domatinostat in Combination With Avelumab in Patients With Treatment-naïve Metastatic Merkel Cell Carcinoma (MERKLIN 1)

Role: lead

NCT03812796Phase 2Unknown

Epigenetic Modulation of the immunE Response in GastrointEstinal Cancers (EMERGE)

Role: collaborator

NCT01065025Phase 1Completed

Open Label, Dose Escalation Trial of Oral Eg5 Kinesin-spindle Inhibitor 4SC-205 in Patients With Advanced Malignancies

Role: lead

NCT01277406Phase 1Completed

4SC-201 (Resminostat) in Advanced Colorectal Carcinoma

Role: lead

NCT01344707Phase 1Completed

Oral Histone Deacetylase Inhibitor 4SC-202 in Patients With Advanced Hematologic Malignancies (TOPAS)

Role: lead

NCT01037478Phase 2Completed

Resminostat (4SC-201) in Relapsed or Refractory Hodgkin's Lymphoma

Role: lead

NCT00943449Phase 2Completed

4SC-201 (Resminostat) and Sorafenib in Advanced Hepatocellular Carcinoma

Role: lead

NCT01010581Phase 2Completed

SC12267 (4SC-101) in Combination With Methotrexate in Patients With Rheumatoid Arthritis

Role: lead

NCT00820365Phase 2Completed

SC12267 (4SC-101) for Treatment of Patients With Inflammatory Bowel Disease

Role: lead

NCT01054937Phase 1Completed

Single Dose Study With 4SC-203 in Healthy Volunteers

Role: lead

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