Mark Sostek, MD - Clinical Trial Investigator | Syfrah

Trials Sponsors Conditions Drugs Pricing

Research Impact

h-index

N/A

Research impact score

Publications

0

Total publications

Trial Results

0

Published trial results

Citations

0

Total citations

Drug Portfolio

DRUG(6)

MIXED(5)

+1 more interventions

9 unique interventions2 categories

Analytics

Trial Phases

Phase 15

Trial Status

Completed5

Role Distribution

Other Roles5

Activity Timeline

Clinical Trials (5)

NCT01325415Phase 1Completed

A Placebo-controlled Four Way Crossover Study to Asses the Effect of a Single Oral Dose of NKTR-118 on QTc Interval in Healthy Male Subjects

Amount of NKTR-118 in BloodVariation in the Heart's Electrical Cycle

Studydirector

NCT01520896Phase 1Completed

Study in Healthy Volunteers to Investigate the Effects of Ketoconazole on the Pharmacokinetics of NKTR-118

BioavailabilityDrug- Drug InteractionsHealthy Volunteers

Studydirector

NCT01533155Phase 1Completed

Study in Healthy Volunteers to Investigate the Effects of Quinidine on the Pharmacokinetics of NKTR-118

Drug Induced Constipation

Studydirector

NCT01533870Phase 1Completed

Study in Healthy Volunteers to Investigate the Effects of Rifampin on the Pharmacokinetics of NKTR-118

Drug Induced Constipation

Studydirector

NCT01594619Phase 1Completed

Study in Healthy Volunteers to Investigate the Effects of Diltiazem on the Pharmacokinetics of Naloxegol

Drug Induced Constipation

Studydirector

Research Network

Collaboration Network

8 collaborators·12 connections

Network Legend

KOL

Current Investigator

CO

High-influence Collaborator

CO

Collaborator

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Research Areas & Affiliations

Therapeutic Areas

Drug Induced Constipation3 Amount of NKTR-118 in Blood1 Biological Availability1 Drug Drug Interactions1 Healthy Volunteers1 Variation in the Heart's Electrical Cycle1

Affiliations

Astrazeneca, Wilmington US

AstraZeneca, Wilmington US

Similar Key Opinion Leaders

Discover other key opinion leaders with similar research profiles, therapeutic areas, and collaboration networks.

10 similar investigators found

Bo Fransson, MD

Astrazeneca, Sodertalje Sweden

Shared therapeutic areas:

Drug Induced ConstipationBiological AvailabilityDrug Drug Interactions+1 more

Worked with same sponsors:

Collaborated on 4 trials

Similarity Score56%

David Matthews, MD

Quintiles, Inc Kansas Overland Park US.

Moderately Similar

Shared therapeutic areas:

Biological AvailabilityDrug Drug InteractionsHealthy Volunteers

Worked with same sponsors:

Collaborated on 1 trial

Similarity Score34%

David Matthews, MD

Quintiles, Overland Park Kansas US

Shared therapeutic areas:

Amount of NKTR-118 in BloodVariation in the Heart's Electrical Cycle

Worked with same sponsors:

Collaborated on 1 trial

Similarity Score24%

Emilie Ramos, MD

AstraZeneca, Alderley Park, UK

Shared therapeutic areas:

Amount of NKTR-118 in BloodVariation in the Heart's Electrical Cycle

Worked with same sponsors:

Collaborated on 1 trial

Similarity Score24%

Kelli Craven, MD

Quintiles, Inc Kansas Overland Park US.

Shared therapeutic areas:

Drug Induced Constipation

Worked with same sponsors:

Collaborated on 1 trial

Similarity Score14%

Phil Leese, MD

Quintiles Kansas United states

Shared therapeutic areas:

Drug Induced Constipation

Worked with same sponsors:

Collaborated on 1 trial

Similarity Score14%

Dave Matthews, MD

Quintiles, Inc Kansas Overland Park US

Shared therapeutic areas:

Drug Induced Constipation

Worked with same sponsors:

Collaborated on 1 trial

Similarity Score14%

Paolo Bonato, PhD

Spaulding Rehabilitation Hospital

Shared therapeutic areas:

Healthy Volunteers

Similarity Score5%

Herbert B Slade, MD

Healthpoint

Shared therapeutic areas:

Healthy Volunteers

Similarity Score5%

Pablo Tebas, MD

University of Pennsylvania

Shared therapeutic areas:

Healthy Volunteers

Worked with same sponsors:

Similarity Score5%

Publications (0)

No publications found for this investigator.

Clinical Trials (5)

Showing 5 of 5 trials

NCT01325415Phase 1StudyDirector

A Placebo-controlled Four Way Crossover Study to Asses the Effect of a Single Oral Dose of NKTR-118 on QTc Interval in Healthy Male Subjects

Amount of NKTR-118 in BloodVariation in the Heart's Electrical Cycle

Completed

NCT01520896Phase 1StudyDirector

Study in Healthy Volunteers to Investigate the Effects of Ketoconazole on the Pharmacokinetics of NKTR-118

BioavailabilityDrug- Drug InteractionsHealthy Volunteers

Completed

NCT01533155Phase 1StudyDirector

Study in Healthy Volunteers to Investigate the Effects of Quinidine on the Pharmacokinetics of NKTR-118

Drug Induced Constipation

Completed

NCT01533870Phase 1StudyDirector

Study in Healthy Volunteers to Investigate the Effects of Rifampin on the Pharmacokinetics of NKTR-118

Drug Induced Constipation

Completed

NCT01594619Phase 1StudyDirector

Study in Healthy Volunteers to Investigate the Effects of Diltiazem on the Pharmacokinetics of Naloxegol

Drug Induced Constipation

Completed

All 5 trials loaded