Success Metrics

Clinical Success Rate
66.7%

Based on 10 completed trials

Completion Rate
67%(10/15)
Active Trials
2(11%)
Results Posted
30%(3 trials)
Terminated
5(26%)

Phase Distribution

Ph phase_2
3
16%
Ph phase_3
3
16%
Ph phase_1
4
21%
Ph phase_4
2
11%

Phase Distribution

4

Early Stage

3

Mid Stage

5

Late Stage

Phase Distribution12 total trials
Phase 1Safety & dosage
4(33.3%)
Phase 2Efficacy & side effects
3(25.0%)
Phase 3Large-scale testing
3(25.0%)
Phase 4Post-market surveillance
2(16.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

62.5%

10 of 16 finished

Non-Completion Rate

37.5%

6 ended early

Currently Active

2

trials recruiting

Total Trials

19

all time

Status Distribution
Active(2)
Completed(10)
Terminated(6)
Other(1)

Detailed Status

Completed10
Terminated5
Recruiting2
unknown1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
19
Active
2
Success Rate
66.7%
Most Advanced
Phase 4

Trials by Phase

Phase 14 (33.3%)
Phase 23 (25.0%)
Phase 33 (25.0%)
Phase 42 (16.7%)

Trials by Status

completed1053%
unknown15%
terminated526%
withdrawn15%
recruiting211%

Recent Activity

Clinical Trials (19)

Showing 19 of 19 trials
NCT05008926Phase 3

The NIPA Study Naloxegol Administration to Prevent Opioids Induced Gastrointestinal Motility Disturbance in Brain Injured PAtients

Recruiting
NCT03087708Phase 2

Naloxegol in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer

Terminated
NCT03720613

Risk of Major Adverse Cardiovascular Events for Naldemedine & Other Medications for Opioid Induced Constipation

Recruiting
NCT02813148

Naloxegol Drug Utilization Post Authorisation Safety Study

Completed
NCT02813369

Naloxegol Health Outcome Post Authorisation Safety Study

Terminated
NCT02099591Phase 1

Phase I Pharmacokinetics and Safety Study of Naloxegol in Paediatric OIC Patients

Completed
NCT03638440

Real World Observational Study of Naloxegol for Patients With Cancer Pain Diagnosed With OIC.

Completed
NCT02813356

Naloxegol US PMR CV Safety.

Unknown
NCT05770960Phase 4

Colonic Motor Patterns in Healthy Volunteers

Completed
NCT04433390Phase 3

Effect of Naloxegol on Postoperative Ileus in Patients Undergoing Cardiac Surgery

Completed
NCT04294550

Study on Quality of Life in Advanced Cancer Patients With Opioid-induced Constipation Treated With Naloxegol

Completed
NCT02705378Phase 3

The Effect of Naloxegol on Refractory Constipation in the Intensive Care Unit

Withdrawn
NCT02745353Phase 2

Naloxegol in Cancer Opioid-Induced Constipation

Terminated
NCT04173858

Evaluation of the Quality of Life of Patients With Opioid-induced Constipation Under Treatment With Naloxegol

Completed
NCT02839889Phase 4

Tolerability, Safety, and Feasibility of Naloxegol in Patients With Cancer and OIC (Opioid Induced Constipation)

Terminated
NCT02998606Phase 2

Movantik for Opioid-Related Esophageal Disorders

Terminated
NCT02737059Phase 1

Effect of Naloxegol on Gastric, Small Bowel, and Colonic Transit in Healthy Subjects

Completed
NCT01623609Phase 1

Open Label, Healthy Volunteers, Bioequivalence Study With Naloxegol

Completed
NCT01594619Phase 1

Study in Healthy Volunteers to Investigate the Effects of Diltiazem on the Pharmacokinetics of Naloxegol

Completed

All 19 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
19