Success Metrics

Clinical Success Rate
82.5%

Based on 33 completed trials

Completion Rate
83%(33/40)
Active Trials
1(2%)
Results Posted
76%(25 trials)
Terminated
7(15%)

Phase Distribution

Ph phase_4
8
17%
Ph phase_1
5
11%
Ph phase_3
16
34%
Ph phase_2
10
21%
Ph not_applicable
4
9%

Phase Distribution

5

Early Stage

10

Mid Stage

24

Late Stage

Phase Distribution43 total trials
Phase 1Safety & dosage
5(11.6%)
Phase 2Efficacy & side effects
10(23.3%)
Phase 3Large-scale testing
16(37.2%)
Phase 4Post-market surveillance
8(18.6%)
N/ANon-phased studies
4(9.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

73.3%

33 of 45 finished

Non-Completion Rate

26.7%

12 ended early

Currently Active

1

trials recruiting

Total Trials

47

all time

Status Distribution
Active(2)
Completed(33)
Terminated(12)

Detailed Status

Completed33
Terminated7
Withdrawn5
Active, not recruiting1
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
47
Active
1
Success Rate
82.5%
Most Advanced
Phase 4

Trials by Phase

Phase 15 (11.6%)
Phase 210 (23.3%)
Phase 316 (37.2%)
Phase 48 (18.6%)
N/A4 (9.3%)

Trials by Status

terminated715%
withdrawn511%
completed3370%
active_not_recruiting12%
not_yet_recruiting12%

Recent Activity

1 active trials
Showing 5 of 47
active_not_recruitingphase_2

The Zonisamide and Reinforcement for Reducing Alcohol Use (ZARRA) Study

NCT05134857
completedphase_3

The Effects of Combination Zonisamide and Bupropion on Switching to an Electronic Cigarette

NCT05205811
completed

Population Pharmacokinetics of Antiepileptic in Pediatrics

NCT03196466
not_yet_recruiting

Real-world Study of Efficacy and Safety of Zonisamide in add-on Therapy for Patients With Focal Epilepsy

NCT06374966
completedphase_3

Interdisciplinary Study of A Novel Anticonvulsant in Alcoholism

NCT02901041
View all 47 trials

Clinical Trials (47)

Showing 20 of 47 trialsScroll for more
NCT05134857Phase 2

The Zonisamide and Reinforcement for Reducing Alcohol Use (ZARRA) Study

Active Not Recruiting
NCT05205811Phase 3

The Effects of Combination Zonisamide and Bupropion on Switching to an Electronic Cigarette

Completed
NCT03196466

Population Pharmacokinetics of Antiepileptic in Pediatrics

Completed
NCT06374966

Real-world Study of Efficacy and Safety of Zonisamide in add-on Therapy for Patients With Focal Epilepsy

Not Yet Recruiting
NCT02901041Phase 3

Interdisciplinary Study of A Novel Anticonvulsant in Alcoholism

Completed
NCT02900352Phase 3

Zonisamide Treatment of Alcohol Use Disorder: an Evaluation of Efficacy and Mechanism of Action

Completed
NCT01766128Phase 2

Study of Zonisamide in Early Parkinson Disease

Withdrawn
NCT04388319Phase 3

Zonisamide/Bupropion Effects on Switching to Electronic Cigarettes

Completed
NCT01127256Phase 4

Comparative Study of Zonisamide and Carbamazepine as an Initial Monotherapy: Efficacy and Safety Evaluation

Completed
NCT01140867Phase 4

Open-label, Multi-center Trial of Zonisamide as Adjunctive Therapy in Patients With Uncontrolled Partial Epilepsy

Completed
NCT03376139Phase 2

Zonisamide Outpatient Study

Withdrawn
NCT00777218Not Applicable

Cognitive Side Effects of Commonly Prescribed Medications in Pediatric Migraine

Withdrawn
NCT02368431Phase 3

Effectiveness of Zonisamide in Alcohol Dependent Veterans

Terminated
NCT01847469Phase 2

Zonisamide in Addition to E-CPT-C for Veterans With PTSD and Comorbid Alcohol Dependence

Completed
NCT01685996Phase 1

Zonisamide Augmentation of Varenicline Treatment for Smoking Cessation

Completed
NCT02049073Phase 1

Prevention of Noise-induced Hearing Loss

Withdrawn
NCT01137890Phase 1

Effect of Zonisamide on Cocaine Reinforcement, Craving, and Relapse

Completed
NCT00398918Not Applicable

Alcohol Self Administration Laboratory

Completed
NCT00692003Phase 3

Adjunctive Zonisamide in Primary Generalised Tonic Clonic Seizures

Terminated
NCT01566370Phase 2

Zonisamide for Heavy Drinkers With Bipolar Disorder

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
47