Success Metrics

Clinical Success Rate
82.5%

Based on 33 completed trials

Completion Rate
83%(33/40)
Active Trials
1(2%)
Results Posted
76%(25 trials)
Terminated
7(15%)

Phase Distribution

Ph phase_1
5
11%
Ph phase_2
10
21%
Ph not_applicable
4
9%
Ph phase_4
8
17%
Ph phase_3
16
34%

Phase Distribution

5

Early Stage

10

Mid Stage

24

Late Stage

Phase Distribution43 total trials
Phase 1Safety & dosage
5(11.6%)
Phase 2Efficacy & side effects
10(23.3%)
Phase 3Large-scale testing
16(37.2%)
Phase 4Post-market surveillance
8(18.6%)
N/ANon-phased studies
4(9.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

73.3%

33 of 45 finished

Non-Completion Rate

26.7%

12 ended early

Currently Active

1

trials recruiting

Total Trials

47

all time

Status Distribution
Active(2)
Completed(33)
Terminated(12)

Detailed Status

Completed33
Terminated7
Withdrawn5
Not yet recruiting1
Recruiting1

Development Timeline

Analytics

Development Status

Total Trials
47
Active
1
Success Rate
82.5%
Most Advanced
Phase 4

Trials by Phase

Phase 15 (11.6%)
Phase 210 (23.3%)
Phase 316 (37.2%)
Phase 48 (18.6%)
N/A4 (9.3%)

Trials by Status

not_yet_recruiting12%
completed3370%
withdrawn511%
recruiting12%
terminated715%

Recent Activity

1 active trials
Showing 5 of 47
completedphase_3

The Effects of Combination Zonisamide and Bupropion on Switching to an Electronic Cigarette

NCT05205811
completed

Population Pharmacokinetics of Antiepileptic in Pediatrics

NCT03196466
recruitingphase_2

The Zonisamide and Reinforcement for Reducing Alcohol Use (ZARRA) Study

NCT05134857
not_yet_recruiting

Real-world Study of Efficacy and Safety of Zonisamide in add-on Therapy for Patients With Focal Epilepsy

NCT06374966
completedphase_3

Interdisciplinary Study of A Novel Anticonvulsant in Alcoholism

NCT02901041
View all 47 trials

Clinical Trials (47)

Showing 20 of 47 trialsScroll for more
NCT05205811Phase 3

The Effects of Combination Zonisamide and Bupropion on Switching to an Electronic Cigarette

Completed
NCT03196466

Population Pharmacokinetics of Antiepileptic in Pediatrics

Completed
NCT05134857Phase 2

The Zonisamide and Reinforcement for Reducing Alcohol Use (ZARRA) Study

Recruiting
NCT06374966

Real-world Study of Efficacy and Safety of Zonisamide in add-on Therapy for Patients With Focal Epilepsy

Not Yet Recruiting
NCT02901041Phase 3

Interdisciplinary Study of A Novel Anticonvulsant in Alcoholism

Completed
NCT02900352Phase 3

Zonisamide Treatment of Alcohol Use Disorder: an Evaluation of Efficacy and Mechanism of Action

Completed
NCT01766128Phase 2

Study of Zonisamide in Early Parkinson Disease

Withdrawn
NCT04388319Phase 3

Zonisamide/Bupropion Effects on Switching to Electronic Cigarettes

Completed
NCT01127256Phase 4

Comparative Study of Zonisamide and Carbamazepine as an Initial Monotherapy: Efficacy and Safety Evaluation

Completed
NCT01140867Phase 4

Open-label, Multi-center Trial of Zonisamide as Adjunctive Therapy in Patients With Uncontrolled Partial Epilepsy

Completed
NCT03376139Phase 2

Zonisamide Outpatient Study

Withdrawn
NCT00777218Not Applicable

Cognitive Side Effects of Commonly Prescribed Medications in Pediatric Migraine

Withdrawn
NCT02368431Phase 3

Effectiveness of Zonisamide in Alcohol Dependent Veterans

Terminated
NCT01847469Phase 2

Zonisamide in Addition to E-CPT-C for Veterans With PTSD and Comorbid Alcohol Dependence

Completed
NCT01685996Phase 1

Zonisamide Augmentation of Varenicline Treatment for Smoking Cessation

Completed
NCT02049073Phase 1

Prevention of Noise-induced Hearing Loss

Withdrawn
NCT01137890Phase 1

Effect of Zonisamide on Cocaine Reinforcement, Craving, and Relapse

Completed
NCT00398918Not Applicable

Alcohol Self Administration Laboratory

Completed
NCT00692003Phase 3

Adjunctive Zonisamide in Primary Generalised Tonic Clonic Seizures

Terminated
NCT01566370Phase 2

Zonisamide for Heavy Drinkers With Bipolar Disorder

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
47