Success Metrics

Clinical Success Rate
93.6%

Based on 44 completed trials

Completion Rate
94%(44/47)
Active Trials
6(9%)
Results Posted
75%(33 trials)
Terminated
3(4%)

Phase Distribution

Ph phase_1
4
6%
Ph early_phase_1
2
3%
Ph phase_2
12
17%
Ph phase_3
21
30%
Ph phase_4
25
36%
Ph not_applicable
1
1%

Phase Distribution

6

Early Stage

12

Mid Stage

46

Late Stage

Phase Distribution65 total trials
Early Phase 1First-in-human
2(3.1%)
Phase 1Safety & dosage
4(6.2%)
Phase 2Efficacy & side effects
12(18.5%)
Phase 3Large-scale testing
21(32.3%)
Phase 4Post-market surveillance
25(38.5%)
N/ANon-phased studies
1(1.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

84.6%

44 of 52 finished

Non-Completion Rate

15.4%

8 ended early

Currently Active

6

trials recruiting

Total Trials

69

all time

Status Distribution
Active(7)
Completed(44)
Terminated(8)
Other(10)

Detailed Status

Completed44
unknown10
Withdrawn5
Recruiting5
Terminated3
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
69
Active
6
Success Rate
93.6%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (3.1%)
Phase 14 (6.2%)
Phase 212 (18.5%)
Phase 321 (32.3%)
Phase 425 (38.5%)
N/A1 (1.5%)

Trials by Status

completed4464%
not_yet_recruiting11%
withdrawn57%
recruiting57%
active_not_recruiting11%
unknown1014%
terminated34%

Recent Activity

Clinical Trials (69)

Showing 20 of 69 trialsScroll for more
NCT07000734Phase 2

Fortifying Healthy Behaviors, Optimizing Medical Therapies and Enhancing Cognitive Function in Older Adults-pilot Study

Completed
NCT06604520Phase 2

Vortioxetine for the Treatment of Mood and Cognitive Symptoms in Frontotemporal Dementia

Recruiting
NCT07266545Phase 4

RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE)

Recruiting
NCT05814640Phase 1

Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD)

Recruiting
NCT07284628Phase 2

Vortioxetine for Newly Diagnosed Glioblastoma

Not Yet Recruiting
NCT03053362Phase 2

THINC-it Vortioxetine - Sensitivity to Change

Completed
NCT05047952Phase 2

Vortioxetine for Post-COVID-19 Condition

Completed
NCT04446039

Non-interventional, Retrospective Cohort Study to Explore Antidepressant Treatment in Korea

Completed
NCT05866575Not Applicable

Prediction of the Therapeutic Response in Depression Based on Neuro-computational Modeling Assessment of Motivation

Recruiting
NCT04895488Phase 2

Cognitive Effects of Adjuvant Vortioxetine in Early Schizophrenia

Recruiting
NCT02357797Phase 4

Adjunctive Vortioxetine in Schizophrenia

Active Not Recruiting
NCT05481957Phase 4

Vortioxetine Adjunctive Treatment in Bipolar Depression

Completed
NCT05840861

Using 18F-FPEB PET to Identify mGLUR5 Availability in Affective Disorders

Unknown
NCT03485274Phase 2

Substance Misuse To Psychiatric Disorders for Cannabis

Completed
NCT04301492Phase 4

Tolerability, Safety and Efficacy of Vortioxetine

Unknown
NCT03779789Phase 4

Vortioxetine in the Elderly vs. Selective Serotonin Reuptake Inhibitors (SSRIs): a Pragmatic Assessment

Completed
NCT05014919Phase 3

Vortioxetine to Prevent Return of Symptoms in Children With Depression

Terminated
NCT02871297Phase 3

Long-term, Open-label, Flexible-dose, Extension Study of Vortioxetine in Child and Adolescent Participants With Major Depressive Disorder (MDD) From 7 to 18 Years of Age

Terminated
NCT03580967Phase 4

Vortioxetine Monotherapy for Major Depressive Disorder in Type 2 Diabetes

Withdrawn
NCT04294654Phase 4

Vortioxetine in Patients With Depression and Early Dementia

Completed

Drug Details

Intervention Type
DRUG
Total Trials
69