Success Metrics

Clinical Success Rate
100.0%

Based on 3 completed trials

Completion Rate
100%(3/3)
Active Trials
10(67%)
Results Posted
33%(1 trials)

Phase Distribution

Ph phase_1
6
40%
Ph phase_2
1
7%
Ph phase_3
4
27%
Ph not_applicable
1
7%

Phase Distribution

6

Early Stage

1

Mid Stage

4

Late Stage

Phase Distribution12 total trials
Phase 1Safety & dosage
6(50.0%)
Phase 2Efficacy & side effects
1(8.3%)
Phase 3Large-scale testing
4(33.3%)
N/ANon-phased studies
1(8.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

100.0%

3 of 3 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

10

trials recruiting

Total Trials

15

all time

Status Distribution
Active(11)
Completed(3)
Other(1)

Detailed Status

Recruiting5
Active, not recruiting5
Completed3
Not yet recruiting1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
15
Active
10
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 16 (50.0%)
Phase 21 (8.3%)
Phase 34 (33.3%)
N/A1 (8.3%)

Trials by Status

recruiting533%
not_yet_recruiting17%
active_not_recruiting533%
completed320%
unknown17%

Recent Activity

Clinical Trials (15)

Showing 15 of 15 trials
NCT06809322Phase 3

Vorasidenib Maintenance for IDH Mutant Astrocytoma

Recruiting
NCT07286292Phase 2

Vorasidenib Study in Pediatric Participants With Grade 2 Astrocytoma or Oligodendroglioma With an IDH1 or IDH2 Mutation

Recruiting
NCT07215910Phase 3

Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

Recruiting
NCT05592743

Vorasidenib Expanded Access Program

Unknown
NCT06969352Not Applicable

A Multicentre, Retrospective-prospective Real-world Study: to Evaluate the Effectiveness and Safety of Vorasidenib in Patients With Isocitrate Dehydrogenase IDH1/2 Mutant Grade 2 Astrocytoma or Oligodendroglioma (VICTORIA Study)

Active Not Recruiting
NCT06478212Phase 1

Vorasidenib in Combination With Temozolomide (TMZ) in IDH-mutant Glioma

Active Not Recruiting
NCT07629089Phase 1

VorAsidenib With Lomustine In Patients With rEcurrent IDH-mutaNT Glioma Harboring IDH1 and/or IDH2 Mutations

Not Yet Recruiting
NCT06780930Phase 3

Phase 3 Study of Vorasidenib (S095032/AG-881) in Asian Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 orIDH2 Mutation

Active Not Recruiting
NCT07235774Phase 1

A Drug-drug Interaction Study of Vorasidenib and a Combined Oral Contraceptive in Healthy Female Participants

Completed
NCT07547163

Patient Voice in the Treatment of Low-grade Gliomas: Use of Patient-reported Outcomes, Vorasidenib and Radiotherapy Compared

Recruiting
NCT05484622Phase 1

Study of Vorasidenib and Pembrolizumab Combination in Recurrent or Progressive IDH-1 Mutant Glioma

Active Not Recruiting
NCT07235748Phase 1

Drug-drug Interaction Study of Vorasidenib With Bupropion, Repaglinide, Flurbiprofen, Omeprazole, Midazolam, and Rosuvastatin in Healthy Adult Participants

Completed
NCT07240662

Vorasidenib in CNS WHO Grade 2 IDH-mutant Diffuse Glioma

Recruiting
NCT04164901Phase 3

Study of Vorasidenib (AG-881) in Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 or IDH2 Mutation (INDIGO)

Active Not Recruiting
NCT05674474Phase 1

A Study of Vorasidenib in Participants With Moderate or Mild Hepatic Impairment and Matched Participants With Normal Hepatic Function

Completed

All 15 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
15