Success Metrics

Clinical Success Rate
66.7%

Based on 6 completed trials

Completion Rate
67%(6/9)
Active Trials
0(0%)
Results Posted
133%(8 trials)
Terminated
3(20%)

Phase Distribution

Ph phase_2
2
13%
Ph phase_1
12
80%
Ph phase_3
1
7%

Phase Distribution

12

Early Stage

2

Mid Stage

1

Late Stage

Phase Distribution15 total trials
Phase 1Safety & dosage
12(80.0%)
Phase 2Efficacy & side effects
2(13.3%)
Phase 3Large-scale testing
1(6.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

40.0%

6 of 15 finished

Non-Completion Rate

60.0%

9 ended early

Currently Active

0

trials recruiting

Total Trials

15

all time

Status Distribution
Completed(6)
Terminated(9)

Detailed Status

Completed6
Withdrawn6
Terminated3

Development Timeline

Analytics

Development Status

Total Trials
15
Active
0
Success Rate
66.7%
Most Advanced
Phase 3

Trials by Phase

Phase 112 (80.0%)
Phase 22 (13.3%)
Phase 31 (6.7%)

Trials by Status

completed640%
terminated320%
withdrawn640%

Recent Activity

Clinical Trials (15)

Showing 15 of 15 trials
NCT00804856Phase 2

Phase I/IIa Trial to Investigate BI 6727 (Volasertib) as Monotherapy or in Combination With Cytarabine in Acute Myeloid Leukaemia

Completed
NCT01772563Phase 1

Investigation of Potential Drug-drug Interaction of Volasertib With Itraconazole in Patients With Various Tumours

Completed
NCT01721876Phase 3

Volasertib in Combination With Low-dose Cytarabine in Patients Aged 65 Years and Above With Previously Untreated Acute Myeloid Leukaemia, Who Are Ineligible for Intensive Remission Induction Therapy (POLO-AML-2)

Completed
NCT01957644Phase 1

Phase I Dose Escalation Trial of Volasertib in Combination With Azacitidine in Patients With MDS or CMML

Terminated
NCT02721875Phase 1

Trial of Volasertib With or Without Azacitidine in Patients With Myelodysplastic Syndromes

Terminated
NCT01971476Phase 1

Open Dose Escalating Trial to Determine the Maximum Tolerated Dose in Paediatric Patients With Advanced Cancers for Whom no Therapy is Known

Completed
NCT02201329Phase 1

Volasertib in Combination With Azacitidine in Japanese Patients With Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

Completed
NCT01662505Phase 1

Volasertib in Japanese Patients With Acute Myeloid Leukemia (AML)

Completed
NCT02905994Phase 1

Volasertib Combined With Induction Chemotherapy in Acute Myeloid Leukemia

Withdrawn
NCT02198482Phase 2

Trial of Intensive Chemotherapy With or Without Volasertib in Patients With Newly Diagnosed High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

Terminated
NCT02875002Phase 1

Study of Volasertib and Belinostat in Patients With Relapsed and Refractory Aggressive B-cell and T-cell Lymphomas

Withdrawn
NCT02527174Phase 1

A Study of Volasertib Plus Induction Chemotherapy for Acute Myeloid Leukemia

Withdrawn
NCT02722135Phase 1

A Study to Find a Safe Dose of Volasertib Given in Addition to Standard Salvage Chemotherapy in Children (Age 3 Months to Less Than 18 Years) With Acute Myeloid Leukaemia, in Whom Front-line Chemotherapy Failed

Withdrawn
NCT02861040Phase 1

Volasertib and Vincristine Sulfate Liposome in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia

Withdrawn
NCT02757248Phase 1

Ph1 Volasertib Plus Romidepsin in R/R PTCL and CTCL

Withdrawn

All 15 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
15