Success Metrics

Clinical Success Rate
90.0%

Based on 18 completed trials

Completion Rate
90%(18/20)
Active Trials
2(8%)
Results Posted
61%(11 trials)
Terminated
2(8%)

Phase Distribution

Ph phase_2
13
50%
Ph phase_3
9
35%
Ph phase_1
4
15%

Phase Distribution

4

Early Stage

13

Mid Stage

9

Late Stage

Phase Distribution26 total trials
Phase 1Safety & dosage
4(15.4%)
Phase 2Efficacy & side effects
13(50.0%)
Phase 3Large-scale testing
9(34.6%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

78.3%

18 of 23 finished

Non-Completion Rate

21.7%

5 ended early

Currently Active

2

trials recruiting

Total Trials

26

all time

Status Distribution
Active(2)
Completed(18)
Terminated(5)
Other(1)

Detailed Status

Completed18
Withdrawn3
Terminated2
Recruiting1
Active, not recruiting1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
26
Active
2
Success Rate
90.0%
Most Advanced
Phase 3

Trials by Phase

Phase 14 (15.4%)
Phase 213 (50.0%)
Phase 39 (34.6%)

Trials by Status

recruiting14%
withdrawn312%
terminated28%
active_not_recruiting14%
unknown14%
completed1869%

Recent Activity

Clinical Trials (26)

Showing 20 of 26 trialsScroll for more
NCT07419295Phase 3

A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)

Recruiting
NCT03390504Phase 3

A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations

Active Not Recruiting
NCT03474107Phase 3

A Study to Evaluate Enfortumab Vedotin Versus (vs) Chemotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Urothelial Cancer (EV-301)

Completed
NCT04527991Phase 3

Study of Sacituzumab Govitecan Versus Physician's Choice of Treatment in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread

Completed
NCT00545766Phase 2

Vinflunine in Hormone Refractory Prostate Cancer (HRPC)

Completed
NCT02256436Phase 3

A Study of Pembrolizumab (MK-3475) Versus Paclitaxel, Docetaxel, or Vinflunine for Participants With Advanced Urothelial Cancer (MK-3475-045/KEYNOTE-045)

Completed
NCT02057913Phase 2

A Phase II Trial of Vinflunine Chemotherapy in Locally-advanced and Metastatic Carcinoma of the Penis (VinCaP)

Completed
NCT02665039Phase 2

A Trial With Vinflunine in Patients With Metastatic Bladder Cancer and Impaired Renal Function

Completed
NCT01091168Phase 3

Trial of Vinflunine Versus Alkylating Agent in Metastatic Breast Cancer

Completed
NCT02302807Phase 3

A Study of Atezolizumab Compared With Chemotherapy in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer [IMvigor211]

Completed
NCT01953003Phase 3

Phase III Study of Vinflunine Plus Capecitabine Versus Capecitabine Alone in Patients With Advanced Breast Cancer

Completed
NCT01844947Phase 1

Phase I Study With Sorafenib in Addition to Vinflunine in Metastatic Transitional Cell Carcinoma of the Urothelial Tract

Completed
NCT01529411Phase 2

Clinical Trial With Vinflunine as Maintenance Therapy in Metastatic Urothelial Cancer

Completed
NCT02347332Phase 3

Phase III Study of Vinflunine Plus Methotrexate Versus Methotrexate Alone in Patients With Head and Neck Cancer

Completed
NCT02845050Phase 1

Phase Ib/II Study Assessing the Neo-adjuvant Combination Therapy of Vinflunine With Cisplatin Followed by Radical Cystectomy in Patients With Muscle-invasive Bladder Cancer (JaNEO)

Withdrawn
NCT00519831Phase 2

Ph II of Vinflunine and Cetuximab in Second Line Treatment of NSCLC

Terminated
NCT00450515Phase 2

Vinflunine and Capecitabine in Treating Patients With Previously Treated Metastatic Breast Cancer

Withdrawn
NCT00389155Phase 2

First-Line Treatment of Advanced Bladder Cancer Randomized vs. Gemcitabine ± Vinflunine in Patients Ineligible to Receive Cisplatin-Based Therapy

Completed
NCT00534807Phase 1

A Study of the Interaction of Rifampin and Vinflunine in Subjects With Advanced Cancer

Withdrawn
NCT01830231Phase 2

Cabazitaxel vs. Vinflunine in Metastatic or Locally Advanced Transitional Cell Carcinoma of the Urothelium (TCCU)

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
26