Success Metrics

Clinical Success Rate
91.8%

Based on 168 completed trials

Completion Rate
92%(168/183)
Active Trials
15(7%)
Results Posted
79%(132 trials)
Terminated
15(7%)

Phase Distribution

Ph phase_4
62
28%
Ph not_applicable
39
17%
Ph phase_1
16
7%
Ph early_phase_1
5
2%
Ph phase_2
63
28%
Ph phase_3
29
13%

Phase Distribution

21

Early Stage

63

Mid Stage

91

Late Stage

Phase Distribution214 total trials
Early Phase 1First-in-human
5(2.3%)
Phase 1Safety & dosage
16(7.5%)
Phase 2Efficacy & side effects
63(29.4%)
Phase 3Large-scale testing
29(13.6%)
Phase 4Post-market surveillance
62(29.0%)
N/ANon-phased studies
39(18.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

86.2%

168 of 195 finished

Non-Completion Rate

13.8%

27 ended early

Currently Active

15

trials recruiting

Total Trials

224

all time

Status Distribution
Active(17)
Completed(168)
Terminated(27)
Other(12)

Detailed Status

Completed168
Terminated15
Withdrawn12
unknown12
Recruiting11
Active, not recruiting4

Development Timeline

Analytics

Development Status

Total Trials
224
Active
15
Success Rate
91.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 15 (2.3%)
Phase 116 (7.5%)
Phase 263 (29.4%)
Phase 329 (13.6%)
Phase 462 (29.0%)
N/A39 (18.2%)

Trials by Status

not_yet_recruiting10%
withdrawn125%
recruiting115%
terminated157%
active_not_recruiting42%
completed16875%
enrolling_by_invitation10%
unknown125%

Recent Activity

Clinical Trials (224)

Showing 20 of 224 trialsScroll for more
NCT07714200Not Applicable

Abstinence Reinforcement Therapy for Veterans Who Smoke Tobacco and Are Experiencing Homelessness

Not Yet Recruiting
NCT02162849Phase 4

Reward Sensitivity and Pharmacotherapy for Smoking Cessation

Active Not Recruiting
NCT07145866Phase 4

Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)

Recruiting
NCT01098955Early Phase 1

Smoking Cessation Treatment for Head & Neck Cancer Patients

Active Not Recruiting
NCT05413122Phase 2

Evaluating Smoking Cessation Interventions for PWH in South Africa

Recruiting
NCT04198116Phase 2

Combining Varenicline and Guanfacine for Smoking Cessation

Completed
NCT06027840Phase 1

Concurrent vs. Sequential Cessation of Dual Cigarette and E-cigarette Use

Completed
NCT06609369Phase 2

Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse

Recruiting
NCT04176172Phase 3

Optimizing Tobacco Use Treatment for PLWHA

Active Not Recruiting
NCT00959972Phase 4

Varenicline Versus Transdermal Nicotine Patch for Smoking Cessation in Patients With Coronary Heart Disease

Completed
NCT04604509Phase 4

Nicotine Replacement Therapy, Counseling, Varenicline, and Bupropion for Smoking Cessation, the PISCES I Trial

Recruiting
NCT02271919Phase 4

Varenicline and Combined NRT for Smoking Cessation

Completed
NCT05642715Not Applicable

Trial of a Harm Reduction Strategy for People With HIV Who Smoke Cigarettes

Recruiting
NCT06006143Phase 2

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2

Active Not Recruiting
NCT06474299Phase 4

The Avenues Study: Dual Use Cessation

Recruiting
NCT06679374Phase 2

Reducing Falls With Varenicline in Hypocholinergic Parkinson Disease

Recruiting
NCT04634071Phase 2

Tobacco Treatment Optimization and Preferences During Concurrent Cancer Treatment

Completed
NCT06883162Phase 3

Cannabis-Tobacco Co-Use Treatment Study

Recruiting
NCT05694637Phase 4

Botswana Smoking and Abstinence Reinforcement Trial

Enrolling By Invitation
NCT06854406Phase 1

A Study of Varenicline in the Treatment of Visceral Sensation

Completed

Drug Details

Intervention Type
DRUG
Total Trials
224