Success Metrics

Clinical Success Rate
97.3%

Based on 36 completed trials

Completion Rate
97%(36/37)
Active Trials
33(40%)
Results Posted
92%(33 trials)
Terminated
1(1%)

Phase Distribution

Ph phase_4
9
11%
Ph phase_2
15
18%
Ph phase_3
39
47%
Ph not_applicable
1
1%
Ph phase_1
4
5%

Phase Distribution

4

Early Stage

15

Mid Stage

48

Late Stage

Phase Distribution68 total trials
Phase 1Safety & dosage
4(5.9%)
Phase 2Efficacy & side effects
15(22.1%)
Phase 3Large-scale testing
39(57.4%)
Phase 4Post-market surveillance
9(13.2%)
N/ANon-phased studies
1(1.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

92.3%

36 of 39 finished

Non-Completion Rate

7.7%

3 ended early

Currently Active

33

trials recruiting

Total Trials

83

all time

Status Distribution
Active(42)
Completed(36)
Terminated(3)
Other(2)

Detailed Status

Completed36
Recruiting23
Active, not recruiting10
Not yet recruiting9
unknown2
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
83
Active
33
Success Rate
97.3%
Most Advanced
Phase 4

Trials by Phase

Phase 14 (5.9%)
Phase 215 (22.1%)
Phase 339 (57.4%)
Phase 49 (13.2%)
N/A1 (1.5%)

Trials by Status

not_yet_recruiting911%
unknown22%
withdrawn22%
recruiting2328%
terminated11%
active_not_recruiting1012%
completed3643%

Recent Activity

Clinical Trials (83)

Showing 20 of 83 trialsScroll for more
NCT06095596Not Applicable

Efficacy and Safety of Vedolizumab Combined With Upadacitinib in Patients With Ulcerative Colitis

Recruiting
NCT05843643Phase 3

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

Active Not Recruiting
NCT07550673Phase 4

Upadacitinib Versus Infliximab as Second-Line Treatment for Acute Severe Ulcerative Colitis(UPRISE)

Recruiting
NCT07546097Phase 4

Comparative Effectiveness of Upadacitinib vs Corticosteroids as First-Line Therapy for Acute Severe Ulcerative Colitis(UPFRONT)

Recruiting
NCT07510191Phase 4

TNFi Plus Low-Dose Upadacitinib vs TNFi Intensification in Crohn's Disease With Suboptimal Response

Recruiting
NCT07425899Phase 1

A Phase 1 Study of the Safety and How the Body Processes ABBV-722 and Upadacitinib After Multiple Oral Doses in Healthy Adult Participants

Recruiting
NCT06012240Phase 3

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata

Recruiting
NCT07502339Phase 4

Upadacitinib in Patients Hospitalized With Acute Severe Ulcerative Colitis

Not Yet Recruiting
NCT06332534Phase 3

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

Recruiting
NCT06016517

Application of the Personalized N-of-1 Trial Design in Patients With Rheumatoid Arthritis

Not Yet Recruiting
NCT03345823Phase 3

A Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Crohn's Disease Who Completed the Studies M14-431 or M14-433

Active Not Recruiting
NCT07448363

Atopic Dermatitis Treated With Dupilumab and JAK Inhibitors in Costa Rica

Not Yet Recruiting
NCT06461897Phase 3

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

Recruiting
NCT07492251Phase 2

Upadacitinib in Adult Patients With Erosive Mucosal Lichen Planus and Lichen Planopilaris: a Prospective Multicenter Randomized Placebo-controlled Study.

Not Yet Recruiting
NCT07472309

Effectiveness and Safety of Upadacitinib for Acute Severe Ulcerative Colitis

Completed
NCT05889182Phase 3

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

Recruiting
NCT07442045

Real-World Effectiveness and Safety of Upadacitinib Plus Vedolizumab vs Upadacitinib Monotherapy During Induction in Moderate-to-Severe Ulcerative Colitis

Recruiting
NCT03725202Phase 3

A Study to Evaluate the Safety and Efficacy of Upadacitinib in Participants With Giant Cell Arteritis

Completed
NCT04169373Phase 3

A Study to Evaluate Efficacy and Safety of Upadacitinib in Adults With Axial Spondyloarthritis

Completed
NCT06701331Phase 3

Safety and Efficacy of Upadacitinib in Combination With Topical Corticosteroids in Children From 2 to Less Than 12 Years of Age in Japan With Moderate to Severe Atopic Dermatitis

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
83