Success Metrics

Clinical Success Rate
95.1%

Based on 39 completed trials

Completion Rate
95%(39/41)
Active Trials
33(38%)
Results Posted
85%(33 trials)
Terminated
2(2%)

Phase Distribution

Ph phase_3
39
44%
Ph phase_1
5
6%
Ph not_applicable
1
1%
Ph phase_2
16
18%
Ph phase_4
10
11%

Phase Distribution

5

Early Stage

16

Mid Stage

49

Late Stage

Phase Distribution71 total trials
Phase 1Safety & dosage
5(7.0%)
Phase 2Efficacy & side effects
16(22.5%)
Phase 3Large-scale testing
39(54.9%)
Phase 4Post-market surveillance
10(14.1%)
N/ANon-phased studies
1(1.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

90.7%

39 of 43 finished

Non-Completion Rate

9.3%

4 ended early

Currently Active

33

trials recruiting

Total Trials

88

all time

Status Distribution
Active(43)
Completed(39)
Terminated(4)
Other(2)

Detailed Status

Completed39
Recruiting20
Active, not recruiting13
Not yet recruiting10
Terminated2
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
88
Active
33
Success Rate
95.1%
Most Advanced
Phase 4

Trials by Phase

Phase 15 (7.0%)
Phase 216 (22.5%)
Phase 339 (54.9%)
Phase 410 (14.1%)
N/A1 (1.4%)

Trials by Status

active_not_recruiting1315%
completed3944%
terminated22%
withdrawn22%
recruiting2023%
unknown22%
not_yet_recruiting1011%

Recent Activity

Clinical Trials (88)

Showing 20 of 88 trialsScroll for more
NCT06461897Phase 3

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

Recruiting
NCT07425899Phase 1

A Phase 1 Study of the Safety and How the Body Processes ABBV-722 and Upadacitinib After Multiple Oral Doses in Healthy Adult Participants

Completed
NCT05609630Phase 3

Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis.

Recruiting
NCT05889182Phase 3

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

Recruiting
NCT03725007Phase 1

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Upadacitinib in Pediatric Subjects With Polyarticular Course Juvenile Idiopathic Arthritis

Active Not Recruiting
NCT06012240Phase 3

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata

Recruiting
NCT07700446Phase 4

Efficacy of Upadacitinib Re-induction Therapy in Patients With Ulcerative Colitis Who Lost Response to 30 mg Maintenance Dose

Not Yet Recruiting
NCT07442045

Real-World Effectiveness and Safety of Upadacitinib Plus Vedolizumab vs Upadacitinib Monotherapy During Induction in Moderate-to-Severe Ulcerative Colitis

Recruiting
NCT07023302Phase 3

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants in Japan With Alopecia Areata

Active Not Recruiting
NCT07727889Phase 2

A 24-Week Real-World Study of Upadacitinib in Moderate-to-Severe Hidradenitis Suppurativa

Active Not Recruiting
NCT06016517

Application of the Personalized N-of-1 Trial Design in Patients With Rheumatoid Arthritis

Not Yet Recruiting
NCT07697547

Efficacy and Safety of Low-Dose Upadacitinib Combined With Ustekinumab in the Treatment of Refractory Crohn's Disease

Completed
NCT07138898Phase 2

Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty

Recruiting
NCT07670156Phase 1

Upadacitinib in Treatment of JAK/STAT Pathway Disorders With Activating Mutations

Not Yet Recruiting
NCT06332534Phase 3

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

Recruiting
NCT03569293Phase 3

Evaluation of Upadacitinib in Adolescent and Adult Patients With Moderate to Severe Atopic Dermatitis (Eczema)

Completed
NCT07546097Phase 4

Comparative Effectiveness of Upadacitinib vs Corticosteroids as First-Line Therapy for Acute Severe Ulcerative Colitis(UPFRONT)

Recruiting
NCT06118411Phase 3

A Study To Assess Adverse Events and Effectiveness of Upadacitinib Oral Tablets in Adult and Adolescent Participants With Vitiligo

Active Not Recruiting
NCT07510191Phase 4

TNFi Plus Low-Dose Upadacitinib vs TNFi Intensification in Crohn's Disease With Suboptimal Response

Recruiting
NCT07352566Phase 4

Utilization of a Microdevice for Psoriasis and Atopic Dermatitis

Not Yet Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
88