Success Metrics

Clinical Success Rate
93.0%

Based on 40 completed trials

Completion Rate
93%(40/43)
Active Trials
34(38%)
Results Posted
83%(33 trials)
Terminated
3(3%)

Phase Distribution

Ph phase_3
40
44%
Ph not_applicable
1
1%
Ph phase_2
16
18%
Ph phase_1
6
7%
Ph phase_4
10
11%

Phase Distribution

6

Early Stage

16

Mid Stage

50

Late Stage

Phase Distribution73 total trials
Phase 1Safety & dosage
6(8.2%)
Phase 2Efficacy & side effects
16(21.9%)
Phase 3Large-scale testing
40(54.8%)
Phase 4Post-market surveillance
10(13.7%)
N/ANon-phased studies
1(1.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

88.9%

40 of 45 finished

Non-Completion Rate

11.1%

5 ended early

Currently Active

34

trials recruiting

Total Trials

90

all time

Status Distribution
Active(43)
Completed(40)
Terminated(5)
Other(2)

Detailed Status

Completed40
Recruiting21
Active, not recruiting13
Not yet recruiting9
Terminated3
unknown2

Development Timeline

Analytics

Development Status

Total Trials
90
Active
34
Success Rate
93.0%
Most Advanced
Phase 4

Trials by Phase

Phase 16 (8.2%)
Phase 216 (21.9%)
Phase 340 (54.8%)
Phase 410 (13.7%)
N/A1 (1.4%)

Trials by Status

unknown22%
terminated33%
completed4044%
recruiting2123%
active_not_recruiting1314%
not_yet_recruiting910%
withdrawn22%

Recent Activity

Clinical Trials (90)

Showing 20 of 90 trialsScroll for more
NCT07772492Phase 3

A Study to Evaluate the Safety and Effectiveness of Upadacitinib in Pediatric Participants With Alopecia Areata

Recruiting
NCT07492251Phase 2

Upadacitinib in Adult Patients With Erosive Mucosal Lichen Planus and Lichen Planopilaris: a Prospective Multicenter Randomized Placebo-controlled Study.

Recruiting
NCT07843693Phase 1

A Study to Evaluate the Safety and Pharmacokinetics of Multiple Doses Upadacitinib, Tofacitinib, and Baricitinib in Healthy Adult Volunteers

Recruiting
NCT07502339Phase 4

Upadacitinib in Patients Hospitalized With Acute Severe Ulcerative Colitis

Not Yet Recruiting
NCT05609630Phase 3

Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis.

Recruiting
NCT07670156Phase 1

Upadacitinib in Treatment of JAK/STAT Pathway Disorders With Activating Mutations

Not Yet Recruiting
NCT06937788

Replication of the Heads Up Atopic Dermatitis Trial With Registry Data

Terminated
NCT05889182Phase 3

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

Active Not Recruiting
NCT04159597

Expanded Access to Upadacitinib

Unknown
NCT05814627Phase 3

Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis

Completed
NCT06461897Phase 3

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

Recruiting
NCT07425899Phase 1

A Phase 1 Study of the Safety and How the Body Processes ABBV-722 and Upadacitinib After Multiple Oral Doses in Healthy Adult Participants

Completed
NCT03725007Phase 1

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Upadacitinib in Pediatric Subjects With Polyarticular Course Juvenile Idiopathic Arthritis

Active Not Recruiting
NCT06012240Phase 3

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata

Recruiting
NCT07442045

Real-World Effectiveness and Safety of Upadacitinib Plus Vedolizumab vs Upadacitinib Monotherapy During Induction in Moderate-to-Severe Ulcerative Colitis

Recruiting
NCT07700446Phase 4

Efficacy of Upadacitinib Re-induction Therapy in Patients With Ulcerative Colitis Who Lost Response to 30 mg Maintenance Dose

Not Yet Recruiting
NCT07023302Phase 3

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants in Japan With Alopecia Areata

Active Not Recruiting
NCT07727889Phase 2

A 24-Week Real-World Study of Upadacitinib in Moderate-to-Severe Hidradenitis Suppurativa

Active Not Recruiting
NCT06016517

Application of the Personalized N-of-1 Trial Design in Patients With Rheumatoid Arthritis

Not Yet Recruiting
NCT07697547

Efficacy and Safety of Low-Dose Upadacitinib Combined With Ustekinumab in the Treatment of Refractory Crohn's Disease

Completed

Drug Details

Intervention Type
DRUG
Total Trials
90