Success Metrics

Clinical Success Rate
66.7%

Based on 8 completed trials

Completion Rate
67%(8/12)
Active Trials
21(51%)
Results Posted
38%(3 trials)
Terminated
4(10%)

Phase Distribution

Ph phase_1
10
24%
Ph phase_2
20
49%
Ph not_applicable
1
2%
Ph phase_3
6
15%

Phase Distribution

10

Early Stage

20

Mid Stage

6

Late Stage

Phase Distribution37 total trials
Phase 1Safety & dosage
10(27.0%)
Phase 2Efficacy & side effects
20(54.1%)
Phase 3Large-scale testing
6(16.2%)
N/ANon-phased studies
1(2.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

61.5%

8 of 13 finished

Non-Completion Rate

38.5%

5 ended early

Currently Active

21

trials recruiting

Total Trials

41

all time

Status Distribution
Active(25)
Completed(8)
Terminated(5)
Other(3)

Detailed Status

Recruiting15
Completed8
Active, not recruiting6
Not yet recruiting4
Terminated4
unknown2

Development Timeline

Analytics

Development Status

Total Trials
41
Active
21
Success Rate
66.7%
Most Advanced
Phase 3

Trials by Phase

Phase 110 (27.0%)
Phase 220 (54.1%)
Phase 36 (16.2%)
N/A1 (2.7%)

Trials by Status

recruiting1537%
withdrawn12%
not_yet_recruiting410%
suspended12%
terminated410%
unknown25%
completed820%
active_not_recruiting615%

Recent Activity

Clinical Trials (41)

Showing 20 of 41 trialsScroll for more
NCT07525206Phase 3

A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer

Recruiting
NCT07527858Phase 2

Study of Denikitug (GS-1811) Given Alone or With Nivolumab or With Chemotherapy in Adults With Advanced Colorectal Cancer

Recruiting
NCT05476796Phase 2

Oxaliplatin ± Nivolumab in Combination With Trifluridine/Tipiracil or 5-fluorouracile in Frail Patients With Advanced, Recurrent or Metastatic Gastric, Oesophageal or Gastroesophageal Junction Cancer

Active Not Recruiting
NCT05719558Phase 1

A Study of ASP1002 in Adults for Treatment of Solid Tumors

Recruiting
NCT05919264Phase 1

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Recruiting
NCT04626635Phase 1

A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers

Active Not Recruiting
NCT04489173Phase 2

TAS102 in Patients With ER-positive, HER2-negative Advanced Breast Cancer

Completed
NCT04564898Phase 1

Trifluridine/Tipiracil in Combination With Capecitabine and Bevacizumab in Metastatic Colorectal Cancer Patients.

Active Not Recruiting
NCT06356311Phase 3

A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015)

Active Not Recruiting
NCT07146646Phase 2

Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer

Recruiting
NCT07270991Phase 3

Trifluridine/Tipiracil + Fruquintinib Versus Trifluridine/Tipiracil Alone for Metastatic Oeso-gastric Adenocarcinoma

Recruiting
NCT05062889Phase 2

Exploiting Circulating Tumour DNA to Intensify the Postoperative Treatment Resected Colon Cancer Patients

Suspended
NCT07381764Phase 2

ROMANCE: "Irinotecan Plus Cetuximab Rechallenge Versus Trifluridine/Tipiracil Plus Bevacizumab in Molecularly Selected Metastatic Colorectal Cancer"

Not Yet Recruiting
NCT06856837Phase 2

- IKF/AIO-QUINTIS - Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable / Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer Without Active Liver Metastases

Recruiting
NCT05029882Phase 1

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Advanced Solid Tumors Receiving Intravenous (IV) ABBV-400 as Monotherapy and in Combination With IV Bevacizumab

Active Not Recruiting
NCT06887218Phase 2

5-Fluorouracil/Leucovorin (5FU/LV) in Combination With Regorafenib in Patients With Metastatic Colorectal Cancer

Recruiting
NCT04166604Phase 2

LONsurf and G-CSF Use: Being On A Right Dose-intensity to Optimize Treatment Efficacy

Active Not Recruiting
NCT07071844Phase 2

BETWEEN: Biweekly Bevacizumab + Trifluridine/Tipiracil to Reduce Grade 3-4 Neutropenia in mCRC Patients

Not Yet Recruiting
NCT07012954Phase 1

ctDNA-Guided Cetuximab or Bevacizumab Plus Trifluridine/Tipiracil in RAS/BRAF Wild-Type mCRC

Recruiting
NCT04393298Phase 1

A Study to Assess the Safety, Pharmacokinetics and Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced Solid Tumors

Completed

Drug Details

Intervention Type
DRUG
Total Trials
41