Success Metrics

Clinical Success Rate
96.3%

Based on 26 completed trials

Completion Rate
96%(26/27)
Active Trials
7(21%)
Results Posted
23%(6 trials)
Terminated
1(3%)

Phase Distribution

Ph phase_1
17
50%
Ph phase_3
1
3%
Ph phase_2
15
44%
Ph early_phase_1
1
3%

Phase Distribution

18

Early Stage

15

Mid Stage

1

Late Stage

Phase Distribution34 total trials
Early Phase 1First-in-human
1(2.9%)
Phase 1Safety & dosage
17(50.0%)
Phase 2Efficacy & side effects
15(44.1%)
Phase 3Large-scale testing
1(2.9%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

96.3%

26 of 27 finished

Non-Completion Rate

3.7%

1 ended early

Currently Active

7

trials recruiting

Total Trials

34

all time

Status Distribution
Active(7)
Completed(26)
Terminated(1)

Detailed Status

Completed26
Active, not recruiting5
Recruiting2
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
34
Active
7
Success Rate
96.3%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (2.9%)
Phase 117 (50.0%)
Phase 215 (44.1%)
Phase 31 (2.9%)

Trials by Status

recruiting26%
terminated13%
completed2676%
active_not_recruiting515%

Recent Activity

Clinical Trials (34)

Showing 20 of 34 trialsScroll for more
NCT06860594Phase 1

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

Recruiting
NCT04234568Phase 1

Testing the Addition of an Anti-cancer Drug, Triapine, to the Usual Radiation-Based Treatment (Lutetium Lu 177 Dotatate) for Neuroendocrine Tumors

Active Not Recruiting
NCT05724108Phase 2

Testing the Effectiveness of an Anti-cancer Drug, Triapine, When Used With Targeted Radiation-based Treatment (Lutetium Lu 177 Dotatate), Compared to Lutetium Lu 177 Dotatate Alone for Metastatic Neuroendocrine Tumors

Active Not Recruiting
NCT02595879Phase 1

Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vaginal Cancer

Active Not Recruiting
NCT02466971Phase 3

Testing the Addition of a New Anti-Cancer Drug, Triapine, to the Usual Chemotherapy Treatment (Cisplatin) During Radiation Therapy for Advanced-stage Cervical and Vaginal Cancers

Active Not Recruiting
NCT04494113Early Phase 1

Testing the Response to the Anti-cancer Drug, Triapine, in Uterine Cancers Using Markers From the Tissue at the Time of Hysterectomy

Active Not Recruiting
NCT06410248Phase 1

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

Recruiting
NCT00075660Phase 2

3-AP in Treating Patients With Previously Untreated Locally Recurrent or Metastatic Renal Cell Carcinoma

Completed
NCT00078975Phase 2

3-AP and Gemcitabine in Treating Patients With Recurrent, Unresectable, or Metastatic Pancreatic Cancer

Completed
NCT00941070Phase 2

Triapine, Cisplatin, and Radiation Therapy in Treating Patients With Cervical Cancer or Vaginal Cancer

Completed
NCT00288093Phase 1

3-AP and Radiation Therapy in Treating Patients With Stage III Pancreatic Cancer That Cannot Be Removed By Surgery

Completed
NCT00075504Phase 2

Triapine and Gemcitabine Hydrochloride in Gallbladder Cancer

Completed
NCT00381550Phase 2

3-AP and Fludarabine in Treating Patients With Myeloproliferative Disorders, Chronic Myelomonocytic Leukemia, or Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia

Completed
NCT00390052Phase 1

3-AP in Treating Patients With Advanced or Metastatic Solid Tumors

Completed
NCT00064064Phase 2

3-AP and Gemcitabine in Treating Patients With Metastatic Non-Small Cell Lung Cancer

Completed
NCT00054015Phase 2

3-AP in Treating Patients With Advanced Prostate Cancer

Completed
NCT00085371Phase 2

Triapine as First-Line or Second-Line Therapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas

Completed
NCT00077545Phase 2

3-AP Plus Cisplatin in Treating Patients With Recurrent or Metastatic Adenocarcinoma of the Esophagus or Gastroesophageal Junction

Completed
NCT00293345Phase 1

3-AP and Gemcitabine in Treating Patients With Advanced Solid Tumors or Lymphoma

Completed
NCT00064051Phase 2

3-AP and Gemcitabine in Treating Patients With Unresectable or Metastatic Pancreatic Cancer

Completed

Drug Details

Intervention Type
DRUG
Total Trials
34