Success Metrics

Clinical Success Rate
96.3%

Based on 26 completed trials

Completion Rate
96%(26/27)
Active Trials
6(18%)
Results Posted
23%(6 trials)
Terminated
1(3%)

Phase Distribution

Ph phase_2
15
44%
Ph early_phase_1
1
3%
Ph phase_3
1
3%
Ph phase_1
17
50%

Phase Distribution

18

Early Stage

15

Mid Stage

1

Late Stage

Phase Distribution34 total trials
Early Phase 1First-in-human
1(2.9%)
Phase 1Safety & dosage
17(50.0%)
Phase 2Efficacy & side effects
15(44.1%)
Phase 3Large-scale testing
1(2.9%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

96.3%

26 of 27 finished

Non-Completion Rate

3.7%

1 ended early

Currently Active

6

trials recruiting

Total Trials

34

all time

Status Distribution
Active(6)
Completed(26)
Terminated(1)
Other(1)

Detailed Status

Completed26
Active, not recruiting5
Recruiting1
Terminated1
Suspended1

Development Timeline

Analytics

Development Status

Total Trials
34
Active
6
Success Rate
96.3%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (2.9%)
Phase 117 (50.0%)
Phase 215 (44.1%)
Phase 31 (2.9%)

Trials by Status

recruiting13%
terminated13%
completed2676%
suspended13%
active_not_recruiting515%

Recent Activity

Clinical Trials (34)

Showing 20 of 34 trialsScroll for more
NCT06410248Phase 1

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

Recruiting
NCT04234568Phase 1

Testing the Addition of an Anti-cancer Drug, Triapine, to the Usual Radiation-Based Treatment (Lutetium Lu 177 Dotatate) for Neuroendocrine Tumors

Active Not Recruiting
NCT02595879Phase 1

Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vaginal Cancer

Active Not Recruiting
NCT06860594Phase 1

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

Suspended
NCT05724108Phase 2

Testing the Effectiveness of an Anti-cancer Drug, Triapine, When Used With Targeted Radiation-based Treatment (Lutetium Lu 177 Dotatate), Compared to Lutetium Lu 177 Dotatate Alone for Metastatic Neuroendocrine Tumors

Active Not Recruiting
NCT04494113Early Phase 1

Testing the Response to the Anti-cancer Drug, Triapine, in Uterine Cancers Using Markers From the Tissue at the Time of Hysterectomy

Active Not Recruiting
NCT02466971Phase 3

Testing the Addition of a New Anti-Cancer Drug, Triapine, to the Usual Chemotherapy Treatment (Cisplatin) During Radiation Therapy for Advanced-stage Cervical and Vaginal Cancers

Active Not Recruiting
NCT00075660Phase 2

3-AP in Treating Patients With Previously Untreated Locally Recurrent or Metastatic Renal Cell Carcinoma

Completed
NCT00078975Phase 2

3-AP and Gemcitabine in Treating Patients With Recurrent, Unresectable, or Metastatic Pancreatic Cancer

Completed
NCT00941070Phase 2

Triapine, Cisplatin, and Radiation Therapy in Treating Patients With Cervical Cancer or Vaginal Cancer

Completed
NCT00288093Phase 1

3-AP and Radiation Therapy in Treating Patients With Stage III Pancreatic Cancer That Cannot Be Removed By Surgery

Completed
NCT00075504Phase 2

Triapine and Gemcitabine Hydrochloride in Gallbladder Cancer

Completed
NCT00381550Phase 2

3-AP and Fludarabine in Treating Patients With Myeloproliferative Disorders, Chronic Myelomonocytic Leukemia, or Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia

Completed
NCT00390052Phase 1

3-AP in Treating Patients With Advanced or Metastatic Solid Tumors

Completed
NCT00064064Phase 2

3-AP and Gemcitabine in Treating Patients With Metastatic Non-Small Cell Lung Cancer

Completed
NCT00054015Phase 2

3-AP in Treating Patients With Advanced Prostate Cancer

Completed
NCT00077545Phase 2

3-AP Plus Cisplatin in Treating Patients With Recurrent or Metastatic Adenocarcinoma of the Esophagus or Gastroesophageal Junction

Completed
NCT00085371Phase 2

Triapine as First-Line or Second-Line Therapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas

Completed
NCT00293345Phase 1

3-AP and Gemcitabine in Treating Patients With Advanced Solid Tumors or Lymphoma

Completed
NCT00064051Phase 2

3-AP and Gemcitabine in Treating Patients With Unresectable or Metastatic Pancreatic Cancer

Completed

Drug Details

Intervention Type
DRUG
Total Trials
34