trametinib
trametinib is a pharmaceutical drug with 176 clinical trials. Currently 61 active trials ongoing. Historical success rate of 67.8%.
Success Metrics
Based on 59 completed trials
Phase Distribution
Phase Distribution
81
Early Stage
73
Mid Stage
12
Late Stage
Highest Phase Reached
Phase 4Trial Status & Enrollment
59.0%
59 of 100 finished
41.0%
41 ended early
61
trials recruiting
176
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
Pediatric Long-Term Follow-up and Rollover Study
Nivolumab With Trametinib and Dabrafenib, or Encorafenib and Binimetinib in Treating Patients With BRAF Mutated Metastatic or Unresectable Stage III-IV Melanoma
Dabrafenib and/or Trametinib Rollover Study
Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments
Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas
Clinical Trials (176)
Pediatric Long-Term Follow-up and Rollover Study
Nivolumab With Trametinib and Dabrafenib, or Encorafenib and Binimetinib in Treating Patients With BRAF Mutated Metastatic or Unresectable Stage III-IV Melanoma
Dabrafenib and/or Trametinib Rollover Study
Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments
Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas
Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Previously Treated Patients With Metastatic, Radio-active Iodine Refractory BRAF V600E Mutation Positive Differentiated Thyroid Cancer
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)
Pan Tumor Rollover Study
Trametinib and Docetaxel in Treating Patients With Recurrent or Stage IV KRAS Mutation Positive Non-small Cell Lung Cancer
Trametinib and Navitoclax in Treating Patients With Advanced or Metastatic Solid Tumors
Trametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic Leukemia
Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer
Trametinib and Hydroxychloroquine in Treating Patients With Pancreatic Cancer
Testing the Addition of Navitoclax to the Combination of Dabrafenib and Trametinib in People Who Have BRAF Mutant Melanoma
Molecular Profiling of Advanced Soft-tissue Sarcomas
24VA021; VATCH Trametinib for Ras/MAPK Pathway VAs
Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.
A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular Alterations/Characteristics in Advanced / Metastatic Tumors.
Dabrafenib With Trametinib in the Adjuvant Treatment of High-risk BRAF V600 Mutation-positive Melanoma (COMBI-AD).
Abbreviated MAPK Targeted Therapy Plus Pembrolizumab in Melanoma
Drug Details
- Intervention Type
- DRUG
- Total Trials
- 176