Trametinib
Trametinib is a pharmaceutical drug with 176 clinical trials. Currently 60 active trials ongoing. Historical success rate of 67.4%.
Success Metrics
Based on 60 completed trials
Phase Distribution
Phase Distribution
81
Early Stage
73
Mid Stage
12
Late Stage
Highest Phase Reached
Phase 4Trial Status & Enrollment
58.8%
60 of 102 finished
41.2%
42 ended early
60
trials recruiting
176
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)
A Study of Dabrafenib and/or Trametinib in Patients With Relapsed and/or Refractory Multiple Myeloma
Trametinib and Docetaxel in Treating Patients With Recurrent or Stage IV KRAS Mutation Positive Non-small Cell Lung Cancer
Pan Tumor Rollover Study
Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas
Clinical Trials (176)
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)
A Study of Dabrafenib and/or Trametinib in Patients With Relapsed and/or Refractory Multiple Myeloma
Trametinib and Docetaxel in Treating Patients With Recurrent or Stage IV KRAS Mutation Positive Non-small Cell Lung Cancer
Pan Tumor Rollover Study
Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas
Neratinib and Everolimus, Palbociclib, or Trametinib in Treating Participants With Refractory and Advanced or Metastatic Solid Tumors With EGFR Mutation/Amplification, HER2 Mutation/Amplification, or HER3/4 Mutation or KRAS Mutation
Trametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic Leukemia
Trametinib and Pembrolizumab in Treating Patients With Recurrent Non-small Cell Lung Cancer That Is Metastatic, Unresectable, or Locally Advanced
Panitumumab With or Without Trametinib in Treating Patients With Stage IV Colorectal Cancer
Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments
Dabrafenib and/or Trametinib Rollover Study
A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular Alterations/Characteristics in Advanced / Metastatic Tumors.
Trametinib in Combination With Paclitaxel in the Treatment of Anaplastic Thyroid Cancer
Pediatric Long-Term Follow-up and Rollover Study
Study of Cemiplimab Combined With Dabrafenib and Trametinib in People With Anaplastic Thyroid Cancer
Neoadjuvant Dabrafenib + Trametinib for AJCC Stage IIIB-C BRAF V600 Mutation Positive Melanoma
Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Previously Treated Patients With Metastatic, Radio-active Iodine Refractory BRAF V600E Mutation Positive Differentiated Thyroid Cancer
Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer
Trametinib With or Without GSK2141795 in Treating Patients With Metastatic Uveal Melanoma
Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)
Drug Details
- Intervention Type
- DRUG
- Total Trials
- 176