Success Metrics

Clinical Success Rate
100.0%

Based on 8 completed trials

Completion Rate
100%(8/8)
Active Trials
8(29%)
Results Posted
0%(0 trials)

Phase Distribution

Ph phase_2
7
25%
Ph phase_4
1
4%
Ph phase_3
3
11%
Ph phase_1
3
11%
Ph not_applicable
4
14%

Phase Distribution

3

Early Stage

7

Mid Stage

4

Late Stage

Phase Distribution18 total trials
Phase 1Safety & dosage
3(16.7%)
Phase 2Efficacy & side effects
7(38.9%)
Phase 3Large-scale testing
3(16.7%)
Phase 4Post-market surveillance
1(5.6%)
N/ANon-phased studies
4(22.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

80.0%

8 of 10 finished

Non-Completion Rate

20.0%

2 ended early

Currently Active

8

trials recruiting

Total Trials

28

all time

Status Distribution
Active(11)
Completed(8)
Terminated(2)
Other(7)

Detailed Status

Completed8
unknown7
Recruiting5
Active, not recruiting3
Withdrawn2
Not yet recruiting2

Development Timeline

Analytics

Development Status

Total Trials
28
Active
8
Success Rate
100.0%
Most Advanced
Phase 4

Trials by Phase

Phase 13 (16.7%)
Phase 27 (38.9%)
Phase 33 (16.7%)
Phase 41 (5.6%)
N/A4 (22.2%)

Trials by Status

recruiting518%
unknown725%
active_not_recruiting311%
withdrawn27%
completed829%
enrolling_by_invitation14%
not_yet_recruiting27%

Recent Activity

Clinical Trials (28)

Showing 20 of 28 trialsScroll for more
NCT04751370Phase 2

Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer

Active Not Recruiting
NCT04703101Phase 1

Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer

Recruiting
NCT06052332Not Applicable

Efficacy and Safety of Conventional Neoadjuvant Therapy Versus Total Neoadjuvant Therapy in Older Patients With Locally Advanced Rectal Cancer

Recruiting
NCT06834126Phase 1

Papaverine in Combination With Radiation Therapy for the Treatment of Locally Advanced Rectal Cancer, DINOMITE Trial

Recruiting
NCT06823297

Can Neoadjuvant Chemoradiotherapy be Ommited in Mid-rectal Cancer

Not Yet Recruiting
NCT06761287Not Applicable

Optimizing Patient Selection for Surgery Using Pathologic Analysis Following Neoadjuvant Therapy in Locally Advanced Rectal Cancer

Recruiting
NCT06931808Phase 4

Intestinal Microbiota Transplantation, Radiochemotherapy and Sintilimab in Localized Advanced Colon Cancer

Enrolling By Invitation
NCT04301557Phase 2

PD1 Antibody Toripalimab and Chemoradiotherapy for dMMR/MSI-H Locally Advanced Colorectal Cancer

Active Not Recruiting
NCT03503630Phase 2

Short-course Radiation Followed by mFOLFOX-6 Plus COMPOUND 2055269 for Locally-advanced Rectal Adenocarcinoma

Unknown
NCT05984485Phase 3

The Efficacy of Primary Total Mesorectal Excision (TME) Surgery Versus Neoadjuvant Chemotherapy Combined With TME Surgery in Low-risk Locally Advanced Rectal Cancer

Recruiting
NCT05830890Not Applicable

Sentinel Lymph Node Biopsy in Rectal Cancer

Unknown
NCT04304209Phase 2

Pd1 Antibody Sintilimab ± Chemoradiotherapy for Locally Advanced Rectal Cancer

Active Not Recruiting
NCT05609149

MRI Features in Neoadjuvant Treatment Decisions for Patients With Rectal Cancer

Completed
NCT05496270

Surgery Alone Versus Neoadjuvant Treatment Followed by Surgery For MRI-defined T3 Mid-low Rectal Cancer

Completed
NCT01308190Phase 3

Preoperative Chemoradiotherapy and Transanal Endoscopic Microsurgery Versus Total Mesorectal Excision in T2-T3s N0, M0 Rectal Cancer

Completed
NCT04200027

Robotic vs. TaTME Rectal Surgery (ROTA STUDY)

Not Yet Recruiting
NCT02864849Phase 2

Total Neoadjuvant Induction and Consolidation CapeOX Plus IMRT With Capecitabine for MRI Defined High-risk Rectal Cancer

Completed
NCT02860234

Tailored Operative or Non-operative Management for Low-risk Rectal Cancer After Intensive Neoadjuvant Treatment

Completed
NCT04745091

MRI Split Scar Sign as a Predictor to Complete Pathologic Response After Neoadjuvant Chemoradiation in Rectal Cancer

Unknown
NCT04405206

Total Neoadjuvant Therapy Followed by 'Watch and Wait' Approach or Organ Preservation for Low-risk Rectal Cancer

Unknown

Drug Details

Intervention Type
PROCEDURE
Total Trials
28