Success Metrics

Clinical Success Rate
66.7%

Based on 20 completed trials

Completion Rate
67%(20/30)
Active Trials
7(17%)
Results Posted
135%(27 trials)
Terminated
10(24%)

Phase Distribution

Ph early_phase_1
1
2%
Ph not_applicable
3
7%
Ph phase_1
12
29%
Ph phase_2
25
60%
Ph phase_3
1
2%

Phase Distribution

13

Early Stage

25

Mid Stage

1

Late Stage

Phase Distribution42 total trials
Early Phase 1First-in-human
1(2.4%)
Phase 1Safety & dosage
12(28.6%)
Phase 2Efficacy & side effects
25(59.5%)
Phase 3Large-scale testing
1(2.4%)
N/ANon-phased studies
3(7.1%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

60.6%

20 of 33 finished

Non-Completion Rate

39.4%

13 ended early

Currently Active

7

trials recruiting

Total Trials

42

all time

Status Distribution
Active(9)
Completed(20)
Terminated(13)

Detailed Status

Completed20
Terminated10
Recruiting5
Withdrawn3
Active, not recruiting2
Not yet recruiting2

Development Timeline

Analytics

Development Status

Total Trials
42
Active
7
Success Rate
66.7%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (2.4%)
Phase 112 (28.6%)
Phase 225 (59.5%)
Phase 31 (2.4%)
N/A3 (7.1%)

Trials by Status

active_not_recruiting25%
terminated1024%
withdrawn37%
not_yet_recruiting25%
completed2048%
recruiting512%

Recent Activity

Clinical Trials (42)

Showing 20 of 42 trialsScroll for more
NCT05027945Phase 2

A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome

Recruiting
NCT01861106Phase 2

Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations

Recruiting
NCT01176006Phase 2

Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency

Active Not Recruiting
NCT04959175Phase 1

Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

Recruiting
NCT05436418Phase 1

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Recruiting
NCT01384513Phase 2

A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

Completed
NCT02918292Phase 2

Optimizing Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502)

Completed
NCT05565105Phase 2

CD34+ Transplants for Leukemia and Lymphoma

Not Yet Recruiting
NCT03674411Phase 2

Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy

Active Not Recruiting
NCT01319565Phase 2

Prospective Randomized Study of Cell Transfer Therapy for Metastatic Melanoma Using Tumor Infiltrating Lymphocytes Plus IL-2 Following Non-Myeloablative Lymphocyte Depleting Chemo Regimen Alone or in Conjunction With 12Gy Total Body Irradiation (TBI...

Completed
NCT04370795Phase 1

Matched Related and Unrelated Donor Stem Cell Transplantation for Severe Combined Immune Deficiency (SCID): Busulfan-based Conditioning With h-ATG, Radiation, and Sirolimus

Withdrawn
NCT07157514Phase 2

Radioimmunotherapy Conditioning With 131I- Apamistamab for Allogeneic Transplant in Relapse/Refractory AML

Not Yet Recruiting
NCT01350258Phase 1

Bone Marrow Transplant Using a Reduced Intensity Regimen That is Given in Two Steps

Terminated
NCT01350245Phase 2

Bone Marrow Transplantation of Patients in Remission Using Partially Matched Relative Donor

Completed
NCT00429143Phase 1

A Two-Step Approach to Bone Marrow Transplant Using Cells From A Partially-Matched Relative

Completed
NCT01532635Phase 2

A Two-Step Approach to Bone Marrow Transplant Using Cells From Two Partially-Matched Relatives

Terminated
NCT02766465Phase 2

Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503)

Completed
NCT02443831Phase 1

CARPALL: Immunotherapy with CD19+CD22 CAR T-cells for CD19+ and CD22+ Acute Lymphoblastic Leukaemia

Recruiting
NCT02441803Phase 2

Allogeneic Hematopoietic Stem Cell Transplantation (AlloSCT) Initial Salvage Therapy for Induction Failure Acute Myeloid Leukemia (AML)

Completed
NCT03734601Phase 2

Total Body Irradiation +/- Total Lymphoid Irradiation & Anti-Thymocyte Globulin in Non-myeloablative Hematopoietic Cell Transplantation

Completed

Drug Details

Intervention Type
PROCEDURE
Total Trials
42