Success Metrics

Clinical Success Rate
80.6%

Based on 25 completed trials

Completion Rate
81%(25/31)
Active Trials
122(43%)
Results Posted
4%(1 trials)
Terminated
6(2%)

Phase Distribution

Ph phase_2
175
62%
Ph phase_1
63
22%
Ph not_applicable
9
3%
Ph phase_3
22
8%
Ph phase_4
2
1%
Ph early_phase_1
2
1%

Phase Distribution

65

Early Stage

175

Mid Stage

24

Late Stage

Phase Distribution273 total trials
Early Phase 1First-in-human
2(0.7%)
Phase 1Safety & dosage
63(23.1%)
Phase 2Efficacy & side effects
175(64.1%)
Phase 3Large-scale testing
22(8.1%)
Phase 4Post-market surveillance
2(0.7%)
N/ANon-phased studies
9(3.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

69.4%

25 of 36 finished

Non-Completion Rate

30.6%

11 ended early

Currently Active

122

trials recruiting

Total Trials

281

all time

Status Distribution
Active(175)
Completed(25)
Terminated(11)
Other(70)

Detailed Status

Recruiting103
unknown70
Not yet recruiting53
Completed25
Active, not recruiting19
Terminated6

Development Timeline

Analytics

Development Status

Total Trials
281
Active
122
Success Rate
80.6%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (0.7%)
Phase 163 (23.1%)
Phase 2175 (64.1%)
Phase 322 (8.1%)
Phase 42 (0.7%)
N/A9 (3.3%)

Trials by Status

recruiting10337%
active_not_recruiting197%
completed259%
terminated62%
unknown7025%
not_yet_recruiting5319%
withdrawn52%

Recent Activity

Clinical Trials (281)

Showing 20 of 281 trialsScroll for more
NCT07677475Phase 2

MRG003 Plus Toripalimab Versus Toripalimab as Neoadjuvant Therapy for PD-L1-Positive, Resectable, Locally Advanced Head and Neck Squamous Cell Carcinoma

Not Yet Recruiting
NCT06457503Phase 4

A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer

Recruiting
NCT04603040Phase 2

A Study to Evaluate the Efficacy and Safety of Toripalimab Injection in the Treatment of Recurrent or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Who Have Failed at Least Two Prior Lines of Therapy and Are Positive Specific Markers

Terminated
NCT07727993Phase 1

Neoadjuvant Propranolol Plus SOX and Toripalimab for Locally Advanced Gastric/GEJ Adenocarcinoma

Not Yet Recruiting
NCT04918186Phase 2

Immunotherapy Platform Study in Platinum Resistant High Grade Serous Ovarian Cancer

Recruiting
NCT07717242Phase 2

Sun Yat-Sen Treatment Strategy for Enhancing Response in Muscle-invasive Bladder Cancer

Recruiting
NCT04374877Phase 1

Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors

Completed
NCT06657144Phase 1

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

Recruiting
NCT06679985Phase 2

A Trial of Casdozokitug in Combination With Toripalimab Plus Bevacizumab in Participants With Unresectable and/or Locally Advanced or Metastatic Hepatocellular Carcinoma

Active Not Recruiting
NCT05635643Phase 1

Study of CHS-114 in Participants With Advanced Solid Tumors

Recruiting
NCT06964906Phase 2

Neoadjuvant High-Intensity Focused Ultrasound (HIFU) Combined With Toripalimab and Chemotherapy for ER-Positive /HER2-Negative Breast Cancer

Recruiting
NCT05813626Phase 2

Neoadjuvant Chemotherapy Plus Toripalimab in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma

Active Not Recruiting
NCT07693959Phase 3

Neoadjuvant RC48 Plus Gemcitabine in HER2-Expressing MIBC

Recruiting
NCT07611825Phase 2

Gut Microbiota Modulation for Immunotherapy Resensitization in Advanced Renal Cell Carcinoma

Recruiting
NCT07685535Phase 2

HAIC + DEB-TACE + Toripalimab + Lenvatinib for Unresectable Intrahepatic Cholangiocarcinoma

Not Yet Recruiting
NCT07680582Early Phase 1

An Exploratory Study of Personalized Cancer Vaccine in Adjuvant Therapy of Solid Tumors

Recruiting
NCT07669220Phase 2

A Multicenter, Randomized Controlled Phase II Study of Short-Course Radiotherapy Followed by Sequential PD-1 Inhibitor and FOLFOX Chemotherapy Versus Long-Course Chemoradiotherapy for High-Risk Locally Advanced pMMR/MSS Lower Rectal Adenocarcinoma (STAR Trial)

Recruiting
NCT06914440Phase 2

Neoadjuvant SBRT Followed by Nab-Paclitaxel Combined With Toripalimab in HR+/HER2- Breast Cancer

Recruiting
NCT06592599Phase 2

Gemcitabine + Docetaxel + Toripalimab Induction in Epstein-Barr Virus (EBV) Associated Nasopharyngeal Carcinoma(NPC)

Recruiting
NCT07657325

Study on MRD Prediction of Efficacy of Toripalimab in the Treatment of High-risk Recurrent Renal Carcinoma

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
281