Success Metrics

Clinical Success Rate
96.1%

Based on 49 completed trials

Completion Rate
96%(49/51)
Active Trials
19(19%)
Results Posted
61%(30 trials)
Terminated
2(2%)

Phase Distribution

Ph early_phase_1
2
2%
Ph not_applicable
5
5%
Ph phase_3
17
17%
Ph phase_4
21
21%
Ph phase_1
12
12%
Ph phase_2
24
24%

Phase Distribution

14

Early Stage

24

Mid Stage

38

Late Stage

Phase Distribution81 total trials
Early Phase 1First-in-human
2(2.5%)
Phase 1Safety & dosage
12(14.8%)
Phase 2Efficacy & side effects
24(29.6%)
Phase 3Large-scale testing
17(21.0%)
Phase 4Post-market surveillance
21(25.9%)
N/ANon-phased studies
5(6.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

94.2%

49 of 52 finished

Non-Completion Rate

5.8%

3 ended early

Currently Active

19

trials recruiting

Total Trials

100

all time

Status Distribution
Active(30)
Completed(49)
Terminated(3)
Other(18)

Detailed Status

Completed49
unknown18
Recruiting15
Not yet recruiting10
Active, not recruiting4
Terminated2

Development Timeline

Analytics

Development Status

Total Trials
100
Active
19
Success Rate
96.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (2.5%)
Phase 112 (14.8%)
Phase 224 (29.6%)
Phase 317 (21.0%)
Phase 421 (25.9%)
N/A5 (6.2%)

Trials by Status

enrolling_by_invitation11%
active_not_recruiting44%
completed4949%
terminated22%
withdrawn11%
recruiting1515%
unknown1818%
not_yet_recruiting1010%

Recent Activity

Clinical Trials (100)

Showing 20 of 100 trialsScroll for more
NCT07547930Phase 2

Tofacitinib for Glucocorticoid-Resistant Moderate-to-Severe Thyroid Eye Disease

Recruiting
NCT04175886

Effects of Tofacitinib on Body Composition, Bone Mineral Density and Bone Marrow Adiposity in Patients With Rheumatoid Arthritis: the TOFAT Project

Completed
NCT06654882Phase 3

Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis

Recruiting
NCT07530367Phase 3

A Phase III Randomized Controlled Trial Evaluating the Efficacy and Safety of Tofacitinib Combined With Imatinib in Patients With Moderate-to-Severe Palmoplantar Pustulosis

Not Yet Recruiting
NCT07281456Phase 2

Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren Disease

Recruiting
NCT07343635Not Applicable

The Efficacy and Safety of Anti-inflammation Treatment (Hirudoid Introduction Followed by Yellow Light Therapy) Combined With Tofacitinib and Doxycycline in Chinese Adult Patients With Mild to Moderate Erythematous Telangiectatic Rosacea

Recruiting
NCT01500551Phase 2

Long-Term Safety Study Of Tofacitinib In Patients With Juvenile Idiopathic Arthritis

Completed
NCT06095128Phase 4

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

Recruiting
NCT07472166Phase 4

Efficacy of Tofacitinib on Skin Thickening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With Methotrexate

Completed
NCT04338204

Observational Study To Assess The Effectiveness and Treatment Adherence Of Tofacitinib of Ulcerative Colitis In Clinical Practice In Sweden

Recruiting
NCT03288324Phase 1

Open-label Study of Tofacitinib for Moderate to Severe Skin Involvement in Young Adults With Lupus

Completed
NCT05662228Phase 2

Therapies for Down Syndrome Regression Disorder

Active Not Recruiting
NCT04624230Phase 3

Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis

Active Not Recruiting
NCT07406204Phase 4

Tofacitinib vs Methotrexate for Severe Alopecia Areata (TOFA-MTX-AA)

Not Yet Recruiting
NCT06688838

Effective Treatment of Jak1/3 Inhibitor in Blau Syndrome

Enrolling By Invitation
NCT07352566Phase 4

Utilization of a Microdevice for Psoriasis and Atopic Dermatitis

Not Yet Recruiting
NCT04424303

Tofacitinib in Adult Patients With Moderate to Severe Ulcerative Colitis

Completed
NCT07297069Phase 2

Combination Therapy With Infliximab and Tofacitinib for Acute Severe Ulcerative Colitis - CINTO Trial

Not Yet Recruiting
NCT04496960Phase 1

Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's Syndrome

Active Not Recruiting
NCT04246372Phase 2

Tofacitinib for Immune Skin Conditions in Down Syndrome

Completed

Drug Details

Intervention Type
DRUG
Total Trials
100