Success Metrics

Clinical Success Rate
81.3%

Based on 13 completed trials

Completion Rate
81%(13/16)
Active Trials
2(11%)
Results Posted
15%(2 trials)
Terminated
3(17%)

Phase Distribution

Ph phase_1
7
39%
Ph phase_2
7
39%
Ph phase_3
4
22%

Phase Distribution

7

Early Stage

7

Mid Stage

4

Late Stage

Phase Distribution18 total trials
Phase 1Safety & dosage
7(38.9%)
Phase 2Efficacy & side effects
7(38.9%)
Phase 3Large-scale testing
4(22.2%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

81.3%

13 of 16 finished

Non-Completion Rate

18.8%

3 ended early

Currently Active

2

trials recruiting

Total Trials

18

all time

Status Distribution
Active(2)
Completed(13)
Terminated(3)

Detailed Status

Completed13
Terminated3
Recruiting2

Development Timeline

Analytics

Development Status

Total Trials
18
Active
2
Success Rate
81.3%
Most Advanced
Phase 3

Trials by Phase

Phase 17 (38.9%)
Phase 27 (38.9%)
Phase 34 (22.2%)

Trials by Status

recruiting211%
completed1372%
terminated317%

Recent Activity

Clinical Trials (18)

Showing 18 of 18 trials
NCT02174549Phase 1

Dose-defining Study of Tirapazamine Combined With Embolization in Liver Cancer

Recruiting
NCT06844357Phase 2

A Phase II/III Trial Comparing Transarterial Tirapazamine Embolization (TATE) With cTACE for Intermediate-stage Liver Cancer.

Recruiting
NCT06848556Phase 1

Evaluate the Effect of Tirazamine on Primary Liver Cancer.

Terminated
NCT03145558Phase 2

TATE Versus TACE in Intermediate Stage HCC

Terminated
NCT00262821Phase 3

Cisplatin and Radiation Therapy With or Without Tirapazamine in Treating Patients With Cervical Cancer

Terminated
NCT00174837Phase 3

TRACE: Tirapazamine-Radiation And Cisplatin Evaluation

Completed
NCT00005078Phase 1

Tirapazamine, Carboplatin, and Paclitaxel in Treating Patients With Advanced Malignant Solid Tumors

Completed
NCT00002774Phase 2

Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer

Completed
NCT00066742Phase 2

Tirapazamine Combined With Chemo and RT in Limited-Stage Small Cell Lung Cancer

Completed
NCT00017459Phase 3

Cisplatin Plus Vinorelbine With or Without Tirapazamine in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

Completed
NCT00098995Phase 1

Tirapazamine, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer

Completed
NCT00006484Phase 3

Combination Chemotherapy With or Without Tirapazamine in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer

Completed
NCT00003288Phase 1

Tirapazamine Plus Cyclophosphamide in Treating Children With Refractory Solid Tumors

Completed
NCT00025363Phase 2

Comparison of Chemotherapy Regimens in Treating Children With Relapsed or Progressive Rhabdomyosarcoma

Completed
NCT00006487Phase 1

S0004: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Limited-stage Small Cell Lung Cancer

Completed
NCT00003369Phase 2

S9717 Tirapazamine Plus Cisplatin in Treating Patients With Metastatic, Recurrent, or Refractory Cervical Cancer

Completed
NCT00020696Phase 2

Tirapazamine Plus Cisplatin in Treating Patients With Persistent or Recurrent Ovarian Epithelial or Primary Peritoneal Cancer

Completed
NCT00033410Phase 1

Chemotherapy, Tirapazamine, and Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer

Completed

All 18 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
18