Success Metrics

Clinical Success Rate
76.4%

Based on 42 completed trials

Completion Rate
76%(42/55)
Active Trials
7(10%)
Results Posted
74%(31 trials)
Terminated
13(18%)

Phase Distribution

Ph not_applicable
4
6%
Ph phase_2
36
50%
Ph phase_1
10
14%
Ph phase_3
6
8%
Ph phase_4
14
19%

Phase Distribution

10

Early Stage

36

Mid Stage

20

Late Stage

Phase Distribution70 total trials
Phase 1Safety & dosage
10(14.3%)
Phase 2Efficacy & side effects
36(51.4%)
Phase 3Large-scale testing
6(8.6%)
Phase 4Post-market surveillance
14(20.0%)
N/ANon-phased studies
4(5.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

73.7%

42 of 57 finished

Non-Completion Rate

26.3%

15 ended early

Currently Active

7

trials recruiting

Total Trials

72

all time

Status Distribution
Active(8)
Completed(42)
Terminated(15)
Other(7)

Detailed Status

Completed42
Terminated13
Recruiting7
unknown7
Withdrawn2
Enrolling by invitation1

Development Timeline

Analytics

Development Status

Total Trials
72
Active
7
Success Rate
76.4%
Most Advanced
Phase 4

Trials by Phase

Phase 110 (14.3%)
Phase 236 (51.4%)
Phase 36 (8.6%)
Phase 414 (20.0%)
N/A4 (5.7%)

Trials by Status

recruiting710%
enrolling_by_invitation11%
completed4258%
unknown710%
terminated1318%
withdrawn23%

Recent Activity

Clinical Trials (72)

Showing 20 of 72 trialsScroll for more
NCT04888741Phase 2

Methods of T Cell Depletion Trial (MoTD)

Recruiting
NCT06083129Phase 3

Phase III Study Comparing GVHD Prophylaxis With ATG-thymoglobulin to ATLG-grafalon in Elderly Patients With Acute Myeloid Leukemia or Myelodysplasic Syndrome and Receiving an Allogeneic Hematopoietic Stem Cell Transplantation With a 10/10 HLA Matched Unrelated Donor

Recruiting
NCT06872333Phase 2

Allo HSCT for High Risk Hemoglobinopathies

Recruiting
NCT03292861Phase 2

The Effect and Safety Profile of Thymoglobulin® in Primary Cardiac Transplant Recipients

Enrolling By Invitation
NCT07052370Phase 1

TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies

Recruiting
NCT03219359Phase 2

Autologous Stem Cell Transplant for Crohn's Disease

Recruiting
NCT02512497Phase 1

Romidepsin Maintenance After Allogeneic Stem Cell Transplantation

Completed
NCT05735717Phase 2

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Recruiting
NCT04046549Phase 2

A Study to Evaluate the Safety and Efficacy of Dual Costimulation Blockade With VIB4920 and Belatacept for Prophylaxis of Allograft Rejection in Adults Receiving a Kidney Transplant

Completed
NCT02582775Phase 2

MT2015-20: Biochemical Correction of Severe EB by Allo HSCT and Serial Donor MSCs

Completed
NCT04302805Phase 3

rATG Versus rATG Combined With Intravenous Immunoglobulin (IVIG) Induction Immunosuppression in HLA Incompatible Transplantation (INHIBIT)

Completed
NCT04009525Phase 4

Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major: A Multicenter, Prospective Clinical Study

Completed
NCT02867800Phase 1

Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease

Completed
NCT02441803Phase 2

Allogeneic Hematopoietic Stem Cell Transplantation (AlloSCT) Initial Salvage Therapy for Induction Failure Acute Myeloid Leukemia (AML)

Completed
NCT01850108Not Applicable

Non-Myeloablative Conditioning and Bone Marrow Transplantation

Unknown
NCT02464878Phase 2

Multicenter Trial of the Effect of AAT on Islet Transplant Engraftment and Durability After Renal Transplant

Completed
NCT00685061Phase 4

Thymoglobulin Versus Campath-1H Versus Daclizumab in Adult, Primary Deceased Donor Renal Transplantation

Completed
NCT01172418Phase 4

Randomized Trial of 2 Antibody Induction Steroid Avoidance Protocols

Completed
NCT00681343Phase 4

Thymoglobulin Versus Campath-1H Versus Daclizumab in Adult, Primary Living Donor Renal Transplantation

Completed
NCT04903054Phase 2

Selective CD28 Blockade in Renal Transplant Recipients

Withdrawn

Drug Details

Intervention Type
DRUG
Total Trials
72