Success Metrics

Clinical Success Rate
83.3%

Based on 10 completed trials

Completion Rate
83%(10/12)
Active Trials
2(11%)
Results Posted
30%(3 trials)
Terminated
2(11%)

Phase Distribution

Ph early_phase_1
1
6%
Ph phase_1
2
11%
Ph phase_2
2
11%
Ph not_applicable
4
22%
Ph phase_3
1
6%

Phase Distribution

3

Early Stage

2

Mid Stage

1

Late Stage

Phase Distribution10 total trials
Early Phase 1First-in-human
1(10.0%)
Phase 1Safety & dosage
2(20.0%)
Phase 2Efficacy & side effects
2(20.0%)
Phase 3Large-scale testing
1(10.0%)
N/ANon-phased studies
4(40.0%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

76.9%

10 of 13 finished

Non-Completion Rate

23.1%

3 ended early

Currently Active

2

trials recruiting

Total Trials

18

all time

Status Distribution
Active(2)
Completed(10)
Terminated(3)
Other(3)

Detailed Status

Completed10
unknown3
Recruiting2
Terminated2
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
18
Active
2
Success Rate
83.3%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (10.0%)
Phase 12 (20.0%)
Phase 22 (20.0%)
Phase 31 (10.0%)
N/A4 (40.0%)

Trials by Status

withdrawn16%
recruiting211%
unknown317%
completed1056%
terminated211%

Recent Activity

Clinical Trials (18)

Showing 18 of 18 trials
NCT04518748Phase 1

Combined Y-90 Selective Internal Radiation Therapy (Y-90 SIRT) and Stereotactic Body Radiation Therapy (SBRT) in Hepatic Malignancy.

Recruiting
NCT04069468

Non-Interventional Registry Study to Evaluate the Effectiveness of TheraSphere® in the Treatment of Hepatocellular Carcinoma (HCC)

Completed
NCT06773845Phase 2

Building Evidence for Ablative Internal Radiation Therapy in Localized HCC Beyond the Up-To-7 Criteria

Recruiting
NCT01349075

TheraSphere for the Treatment of Unresectable Hepatocellular Carcinoma

Completed
NCT06030232

Transarterial Radioembolization (TARE) in COlorectal MEtastasis of Liver

Completed
NCT00906984

TheraSphere® for Treatment of Unresectable Hepatocellular Carcinoma

Unknown
NCT01556490Not Applicable

Efficacy Evaluation of TheraSphere in Patients With Inoperable Liver Cancer

Completed
NCT04659382Phase 2

Study to Evaluate Efficacy and Safety of Selective Internal Radiation Therapy Plus Xelox, Bevacizumab and Atezolizumab (Immune Chekpoint Inhibitor) in Patients With Liver-dominant Metastatic Colorectal Cancer

Unknown
NCT02072356Early Phase 1

Radiolabeled Glass Beads in Treating Patients With Liver Cancer That Cannot be Removed by Surgery

Completed
NCT01483027Not Applicable

Efficacy Evaluation of TheraSphere Following Failed First Line Chemotherapy in Metastatic Colorectal Cancer

Completed
NCT04090645Not Applicable

TheraSphere & Treatment of Unresectable Primary or Unresectable Secondary Liver Cancer

Completed
NCT01887717Phase 3

Efficacy Evaluation of TheraSphere to Treat Inoperable Liver Cancer With Blockage of the Portal Vein

Terminated
NCT03516695

RadioEmbolization for the ADvancement of Y90 Glass Microspheres Registry

Terminated
NCT03295006

A TheraSphere® Advanced Dosimetry Retrospective Global Study in HCC

Completed
NCT00877136

A Treatment of Unresectable Hepatocellular Carcinoma With TheraSphere®

Completed
NCT01076517

A Humanitarian Device Exemption Treatment Protocol of TheraSphere For Treatment of Unresectable Hepatocellular Carcinoma

Unknown
NCT01864070Phase 1

Phase 1 TheraSphere + Everolimus With Neuroendocrine Tumors (NETs) + Liver Only or Liver Dominant Disease

Withdrawn
NCT01556282Not Applicable

TheraSpheres Treatment for Unresectable Hepatocarcinoma and Portal Vein Thrombosis

Completed

All 18 trials loaded

Drug Details

Intervention Type
DEVICE
Total Trials
18