Tepotinib
Tepotinib is a pharmaceutical drug with 23 clinical trials. Currently 10 active trials ongoing. Historical success rate of 80.0%.
Success Metrics
Based on 8 completed trials
Phase Distribution
Phase Distribution
13
Early Stage
9
Mid Stage
1
Late Stage
Highest Phase Reached
Phase 3Trial Status & Enrollment
72.7%
8 of 11 finished
27.3%
3 ended early
10
trials recruiting
23
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
Tepotinib Phase II in NSCLC Harboring MET Alterations (VISION)
A Study of Tepotinib Plus Osimertinib in Osimertinib Relapsed MET Amplified NSCLC (INSIGHT 2)
A Study of Tepotinib and Ivonescimab in People With Non-Small Cell Lung Cancer
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)
POTENT - Tepotinib in Combination With Pembrolizumab in NSCLC
Clinical Trials (23)
Tepotinib Phase II in NSCLC Harboring MET Alterations (VISION)
A Study of Tepotinib Plus Osimertinib in Osimertinib Relapsed MET Amplified NSCLC (INSIGHT 2)
A Study of Tepotinib and Ivonescimab in People With Non-Small Cell Lung Cancer
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)
POTENT - Tepotinib in Combination With Pembrolizumab in NSCLC
PhI/II Study of Amivantamab and Tepotinib Combo in MET-altered Non-small Cell Lung Cancer
Lazertinib & Tepotinib for EGFR Mutant NSCLC in MET Overexpressed or Amplified Who Progressed After Lazertinib Treatment
Tepotinib vs Standard Treatment in Patients With Advanced MET Exon 14 Mutated Non-Small Cell Lung Cancer Previously Treated
Tepotinib Hepatic Impairment Trial
The Finnish National Study to Facilitate Patient Access to Targeted Anti-cancer Drugs
A Phase 1a/1b Study to Determine the Recommended Phase 2 Dose, of Tepotinib in Participants With MET Alterations and Brain Tumors
Tepotinib Drug-Drug Interaction Study With Carbamazepine in Healthy Participants
The Drug Rediscovery Protocol (DRUP Trial)
CNS Dose Escalation/Expansion of Tepotinib in MET-driven NSCLC
The Rome Trial From Histology to Target: the Road to Personalize Target Therapy and Immunotherapy
Effect of Tepotinib on the PK of the P-gp Substrate Dabigatran Etexilate
Effect of Tepotinib on PK of CYP3A Substrate Midazolam
Effect of a Proton Pump Inhibitor on the PK of Tepotinib
Study of Tepotinib Combined With Cetuximab in Participants With Left-Sided RAS/BRAF Wild Type Metastatic Colorectal Cancer (PERSPECTIVE)
Tepotinib With Gefitinib in Participants With Locally Advanced or Metastatic NSCLC (INSIGHT)
Drug Details
- Intervention Type
- DRUG
- Total Trials
- 23