Tepotinib
Tepotinib is a pharmaceutical drug with 22 clinical trials. Currently 9 active trials ongoing. Historical success rate of 80.0%.
Success Metrics
Based on 8 completed trials
Phase Distribution
Phase Distribution
12
Early Stage
9
Mid Stage
1
Late Stage
Highest Phase Reached
Phase 3Trial Status & Enrollment
72.7%
8 of 11 finished
27.3%
3 ended early
9
trials recruiting
22
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)
POTENT - Tepotinib in Combination With Pembrolizumab in NSCLC
Tepotinib Phase II in NSCLC Harboring MET Alterations (VISION)
PhI/II Study of Amivantamab and Tepotinib Combo in MET-altered Non-small Cell Lung Cancer
A Study of Tepotinib Plus Osimertinib in Osimertinib Relapsed MET Amplified NSCLC (INSIGHT 2)
Clinical Trials (22)
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)
POTENT - Tepotinib in Combination With Pembrolizumab in NSCLC
Tepotinib Phase II in NSCLC Harboring MET Alterations (VISION)
PhI/II Study of Amivantamab and Tepotinib Combo in MET-altered Non-small Cell Lung Cancer
A Study of Tepotinib Plus Osimertinib in Osimertinib Relapsed MET Amplified NSCLC (INSIGHT 2)
Lazertinib & Tepotinib for EGFR Mutant NSCLC in MET Overexpressed or Amplified Who Progressed After Lazertinib Treatment
Tepotinib vs Standard Treatment in Patients With Advanced MET Exon 14 Mutated Non-Small Cell Lung Cancer Previously Treated
Tepotinib Hepatic Impairment Trial
The Finnish National Study to Facilitate Patient Access to Targeted Anti-cancer Drugs
A Phase 1a/1b Study to Determine the Recommended Phase 2 Dose, of Tepotinib in Participants With MET Alterations and Brain Tumors
Tepotinib Drug-Drug Interaction Study With Carbamazepine in Healthy Participants
The Drug Rediscovery Protocol (DRUP Trial)
CNS Dose Escalation/Expansion of Tepotinib in MET-driven NSCLC
The Rome Trial From Histology to Target: the Road to Personalize Target Therapy and Immunotherapy
Effect of Tepotinib on the PK of the P-gp Substrate Dabigatran Etexilate
Effect of Tepotinib on PK of CYP3A Substrate Midazolam
Effect of a Proton Pump Inhibitor on the PK of Tepotinib
Study of Tepotinib Combined With Cetuximab in Participants With Left-Sided RAS/BRAF Wild Type Metastatic Colorectal Cancer (PERSPECTIVE)
Tepotinib With Gefitinib in Participants With Locally Advanced or Metastatic NSCLC (INSIGHT)
c-Met Second-Line Hepatocellular Carcinoma
Drug Details
- Intervention Type
- DRUG
- Total Trials
- 22