Success Metrics

Clinical Success Rate
77.8%

Based on 7 completed trials

Completion Rate
78%(7/9)
Active Trials
0(0%)
Results Posted
57%(4 trials)
Terminated
2(18%)

Phase Distribution

Ph phase_2
1
9%
Ph phase_1
2
18%
Ph early_phase_1
1
9%
Ph phase_3
3
27%
Ph phase_4
1
9%

Phase Distribution

3

Early Stage

1

Mid Stage

4

Late Stage

Phase Distribution8 total trials
Early Phase 1First-in-human
1(12.5%)
Phase 1Safety & dosage
2(25.0%)
Phase 2Efficacy & side effects
1(12.5%)
Phase 3Large-scale testing
3(37.5%)
Phase 4Post-market surveillance
1(12.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

70.0%

7 of 10 finished

Non-Completion Rate

30.0%

3 ended early

Currently Active

0

trials recruiting

Total Trials

11

all time

Status Distribution
Active(1)
Completed(7)
Terminated(3)

Detailed Status

Completed7
Terminated2
Withdrawn1
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
11
Active
0
Success Rate
77.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (12.5%)
Phase 12 (25.0%)
Phase 21 (12.5%)
Phase 33 (37.5%)
Phase 41 (12.5%)

Trials by Status

terminated218%
completed764%
withdrawn19%
not_yet_recruiting19%

Recent Activity

0 active trials
Showing 5 of 11
withdrawnearly_phase_1

A Study in Chronic Hepatitis B e-Antigen Negative Participants After Discontinuation of Nucleos(t)Ide Analog (NA) Treatment

NCT05550519
not_yet_recruiting

Effect of Tenofovir (TDF) on Renal Function in Patients With Chronic Hepatitis B

NCT06896630
completedphase_2

A Study of JNJ 73763989+JNJ 56136379+Nucleos(t)Ide Analog (NA) Regimen Compared to NA Alone in e Antigen Negative Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection

NCT04129554
terminatedphase_1

A Single and Multiple Ascending Dose Study of JNJ-64457744

NCT05423106
completed

Study of Effects of Tenofovir on Bone Health and Kidneys During Pregnancy and Breastfeeding

NCT01066858
View all 11 trials

Clinical Trials (11)

Showing 11 of 11 trials
NCT05550519Early Phase 1

A Study in Chronic Hepatitis B e-Antigen Negative Participants After Discontinuation of Nucleos(t)Ide Analog (NA) Treatment

Withdrawn
NCT06896630

Effect of Tenofovir (TDF) on Renal Function in Patients With Chronic Hepatitis B

Not Yet Recruiting
NCT04129554Phase 2

A Study of JNJ 73763989+JNJ 56136379+Nucleos(t)Ide Analog (NA) Regimen Compared to NA Alone in e Antigen Negative Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection

Completed
NCT05423106Phase 1

A Single and Multiple Ascending Dose Study of JNJ-64457744

Terminated
NCT01066858

Study of Effects of Tenofovir on Bone Health and Kidneys During Pregnancy and Breastfeeding

Completed
NCT00557245Phase 3

Pre-Exposure Prophylaxis to Prevent HIV-1 Acquisition Within HIV-1 Discordant Couples

Completed
NCT02258581

Long Term Follow-up Registry of Individuals Treated in A Gilead-Sponsored Trial in Individuals With Chronic Hepatitis B Infection

Terminated
NCT01040091Phase 1

Evaluation of the Cellular Pharmacology of Tenofovir and Emtricitabine According to HIV Infection Status

Completed
NCT00734162Phase 3

Evaluation of Tenofovir Disoproxil Fumarate in Adolescents With Chronic Hepatitis B Infection

Completed
NCT00112047Phase 3

Tenofovir Disoproxil Fumarate/Emtricitabine/Efavirenz Versus Combivir/Efavirenz in Antiretroviral-Naive HIV-1 Infected Subjects

Completed
NCT01074645Phase 4

Randomized Controlled Trial of Tenofovir in Patients of Reactivation of Hepatitis B Presenting as Acute on Chronic Liver Failure

Completed

All 11 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
11