Success Metrics

Clinical Success Rate
76.5%

Based on 13 completed trials

Completion Rate
76%(13/17)
Active Trials
3(13%)
Results Posted
69%(9 trials)
Terminated
4(17%)

Phase Distribution

Ph phase_3
1
4%
Ph phase_2
9
38%
Ph not_applicable
1
4%
Ph phase_4
6
25%
Ph phase_1
3
13%

Phase Distribution

3

Early Stage

9

Mid Stage

7

Late Stage

Phase Distribution20 total trials
Phase 1Safety & dosage
3(15.0%)
Phase 2Efficacy & side effects
9(45.0%)
Phase 3Large-scale testing
1(5.0%)
Phase 4Post-market surveillance
6(30.0%)
N/ANon-phased studies
1(5.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

76.5%

13 of 17 finished

Non-Completion Rate

23.5%

4 ended early

Currently Active

3

trials recruiting

Total Trials

24

all time

Status Distribution
Active(3)
Completed(13)
Terminated(4)
Other(4)

Detailed Status

Completed13
Terminated4
unknown4
Active, not recruiting3

Development Timeline

Analytics

Development Status

Total Trials
24
Active
3
Success Rate
76.5%
Most Advanced
Phase 4

Trials by Phase

Phase 13 (15.0%)
Phase 29 (45.0%)
Phase 31 (5.0%)
Phase 46 (30.0%)
N/A1 (5.0%)

Trials by Status

completed1354%
active_not_recruiting313%
terminated417%
unknown417%

Recent Activity

Clinical Trials (24)

Showing 20 of 24 trialsScroll for more
NCT02577029Phase 2

Study of ARC-520 With or Without Other Drugs Used in the Treatment of Chronic Chronic Hepatitis B Virus (HBV)

Terminated
NCT04453436

HIV Drug Resistance Among Individuals Failing Tenofovir/Lamivudine and Dolutegravir First Line Regimen in Brazil

Active Not Recruiting
NCT04439539Phase 2

A Study of JNJ-73763989, Pegylated Interferon Alpha-2a, Nucleos(t)Ide Analog (NA) With or Without JNJ-56136379 in Treatment-naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) Infection

Completed
NCT05123599Phase 1

A Study of JNJ-73763989, JNJ-64300535, and Nucleos(t)Ide Analogs in Virologically Suppressed, Hepatitis B e Antigen (HBeAg)- Negative Participants With Chronic Hepatitis B Virus Infection

Completed
NCT04585789Phase 2

A Study to Assess Intrahepatic and Peripheral Changes of Immunologic and Virologic Markers in Chronic Hepatitis B Virus Infection

Completed
NCT05275023Phase 2

An Efficacy and Safety Study of a Combination of JNJ-73763989, Nucleos(t)Ide Analogs (NA), and a Programmed Cell Death Protein Receptor-1 (PD-1) Inhibitor in Chronic Hepatitis B Participants

Completed
NCT04535544Phase 2

A Study of JNJ-73763989 + Nucleos(t)Ide Analog in Participants Co-Infected With Hepatitis B and Hepatitis D Virus

Completed
NCT02344498

Treatment of Hepatitis B in Resource-limited Settings - a Pilot Program in East Africa

Active Not Recruiting
NCT04667104Phase 2

A Study of JNJ-73763989, JNJ-56136379, Nucleos(t)Ide Analogs, and Pegylated Interferon Alpha-2a in Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection

Completed
NCT05005507Phase 2

A Study of JNJ-73763989, Pegylated Interferon Alpha-2a and Nucleos(t)Ide Analogs in Participants With Chronic Hepatitis B Virus Infection

Terminated
NCT03485534Phase 4

Evaluate the Efficacy and Safety to Tenofovir Disoproxil in Chronic Hepatitis B Patients

Completed
NCT02322099Phase 4

Alendronate for Prevention of AntiRetroviral Therapy-associated Bone Loss

Terminated
NCT04032860Phase 4

RCT of Different Effects of Nucleot(s)Ide Analogues on the Prognosis of HBV-HCC Patients After Curative Resection

Active Not Recruiting
NCT02555943Phase 2

DAAs Treatment for Chronic HCV/HBV Co-infection Patients(DASCO)

Completed
NCT00119106Phase 2

Bangkok Tenofovir Study, an HIV Pre-exposure Prophylaxis Trial, Bangkok, Thailand

Completed
NCT02129829

PROLIFICA - West African Treatment Cohort for Hepatitis B

Completed
NCT02186574Phase 3

Tenofovir to Prevent HBV Reactivation

Unknown
NCT04160897

Risk of Hepatocellular Carcinoma in Patients Treated With ETV vs TDF for Chronic Hepatitis B With Compensated Cirrhosis

Unknown
NCT02774837Phase 4

Tenofovir Versus Tenofovir + Telbivudine for Chronic Hepatitis B

Unknown
NCT02904369Phase 1

PK and PD Study of Oral F/TAF for HIV Prevention

Completed

Drug Details

Intervention Type
DRUG
Total Trials
24