Success Metrics

Clinical Success Rate
81.1%

Based on 30 completed trials

Completion Rate
81%(30/37)
Active Trials
12(21%)
Results Posted
47%(14 trials)
Terminated
7(12%)

Phase Distribution

Ph phase_1
1
2%
Ph phase_2
20
34%
Ph phase_3
28
48%
Ph phase_4
5
9%

Phase Distribution

1

Early Stage

20

Mid Stage

33

Late Stage

Phase Distribution54 total trials
Phase 1Safety & dosage
1(1.9%)
Phase 2Efficacy & side effects
20(37.0%)
Phase 3Large-scale testing
28(51.9%)
Phase 4Post-market surveillance
5(9.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.0%

30 of 40 finished

Non-Completion Rate

25.0%

10 ended early

Currently Active

12

trials recruiting

Total Trials

58

all time

Status Distribution
Active(13)
Completed(30)
Terminated(10)
Other(5)

Detailed Status

Completed30
Recruiting12
Terminated7
unknown5
Withdrawn3
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
58
Active
12
Success Rate
81.1%
Most Advanced
Phase 4

Trials by Phase

Phase 11 (1.9%)
Phase 220 (37.0%)
Phase 328 (51.9%)
Phase 45 (9.3%)

Trials by Status

terminated712%
unknown59%
withdrawn35%
not_yet_recruiting12%
completed3052%
recruiting1221%

Recent Activity

Clinical Trials (58)

Showing 20 of 58 trialsScroll for more
NCT07361302Phase 3

A Study to Test if Tenecteplase Helps People to Recover From an Acute Stroke When Given More Than 4.5 Hours After the Person Was Last Seen Well

Recruiting
NCT05105633Phase 2

Extending the Time Window for Tenecteplase by Recanalization of Basilar Artery Occlusion in Posterior Circulation Stroke

Recruiting
NCT07536165

Extended Time Window Intravenous Tenecteplase Thrombolysis Registry for Acute Ischemic Stroke

Not Yet Recruiting
NCT06658197Phase 3

Efficacy and Safety of Tenecteplase Bridging Mechanical Thrombectomy for Acute Large Vessel Occlusion Stroke

Recruiting
NCT07375966Phase 2

Repeated Intravenous Thrombolysis for Ischemic Stroke With Medium to Large Vessel Occlusion Presenting Within 4.5 Hours of Onset With Tenecteplase (RITIS-TNK2)

Recruiting
NCT07375953Phase 2

Repeated Intravenous Thrombolysis for Ischemic Stroke Within 3.0 Hours of Onset With Tenecteplase (RITIS-TNK)

Recruiting
NCT05701956Phase 3

Intravenous Tenecteplase Plus EVT Versus EVT Alone on 4.5 to 24 Hours After Basilar Artery Occlusion

Completed
NCT05499832Phase 3

Safety and Efficacy of Intra-arterial Tenecteplase for Noncomplete Reperfusion of Intracranial Occlusions

Completed
NCT06949228Phase 2

Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy (ALLY) II Trial

Recruiting
NCT07271342

Observational RegIstry of Effectiveness and Safety of teNecTeplase in reAl worLd Settings in China

Recruiting
NCT06221371Phase 3

Endovascular Treatment With or Without Preceding Intravenous Tenecteplase (TNK) in Patients With Late-window acUte Ischemic Stroke Due to Middle Cerebral Artery Occlusion

Completed
NCT06196320Phase 3

Tenecteplase Reperfusion Therapy in Acute Ischaemic Cerebrovascular Events-5

Completed
NCT06320431Phase 3

ACT-GLOBAL THROMBOLYSIS (ACT-WHEN-001) Domain Within the ACT-GLOBAL Adaptive Platform Trial-NCT06352632

Recruiting
NCT06010628Phase 4

Tenecteplase for Acute Ischemic Stroke Within 4.5 to 6 Hours of Onset (EXIT-BT2)

Recruiting
NCT05657457Phase 3

Improving Neurological Outcome for Acute Basilar Artery Occlusion With Sufficient Recanalization After Thrombectomy by Intraarterial Tenecteplase (INSIST-IT)

Terminated
NCT05657470Phase 2

Rescue Thrombolysis for Medium Vessel Occlusion (RESCUE-TNK)

Completed
NCT05199194Phase 3

Randomization to Endovascular Treatment Alone or Preceded by Systemic Thrombolysis With Tenecteplase in Ischemic Stroke

Recruiting
NCT05657444Phase 3

Intra-arterial Tenecteplase During First Thrombectomy Attempt for Acute Stroke (BRETIS-TNK II)

Completed
NCT02301910Phase 3

Single Bolus Recombinant Nonimmunogenic Staphylokinase Versus Single Bolus Tenecteplase (Metalyse) in STEMI

Completed
NCT03854500Phase 3

The Norwegian Tenecteplase Stroke Trial 2

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
58