Success Metrics

Clinical Success Rate
80.7%

Based on 117 completed trials

Completion Rate
81%(117/145)
Active Trials
13(8%)
Results Posted
50%(59 trials)
Terminated
28(17%)

Phase Distribution

Ph early_phase_1
3
2%
Ph phase_2
71
42%
Ph phase_3
5
3%
Ph phase_1
81
48%
Ph phase_4
1
1%
Ph not_applicable
4
2%

Phase Distribution

84

Early Stage

71

Mid Stage

6

Late Stage

Phase Distribution165 total trials
Early Phase 1First-in-human
3(1.8%)
Phase 1Safety & dosage
81(49.1%)
Phase 2Efficacy & side effects
71(43.0%)
Phase 3Large-scale testing
5(3.0%)
Phase 4Post-market surveillance
1(0.6%)
N/ANon-phased studies
4(2.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

77.5%

117 of 151 finished

Non-Completion Rate

22.5%

34 ended early

Currently Active

13

trials recruiting

Total Trials

169

all time

Status Distribution
Active(13)
Completed(117)
Terminated(34)
Other(5)

Detailed Status

Completed117
Terminated28
Active, not recruiting8
Withdrawn6
Recruiting5
unknown5

Development Timeline

Analytics

Development Status

Total Trials
169
Active
13
Success Rate
80.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (1.8%)
Phase 181 (49.1%)
Phase 271 (43.0%)
Phase 35 (3.0%)
Phase 41 (0.6%)
N/A4 (2.4%)

Trials by Status

recruiting53%
terminated2817%
completed11769%
unknown53%
withdrawn64%
active_not_recruiting85%

Recent Activity

Clinical Trials (169)

Showing 20 of 169 trialsScroll for more
NCT00977574Phase 2

Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer

Active Not Recruiting
NCT02567435Phase 3

Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

Active Not Recruiting
NCT03203525Phase 1

Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer

Terminated
NCT01087554Phase 1

Sirolimus or Everolimus or Temsirolimus and Vorinostat in Advanced Cancer

Active Not Recruiting
NCT00980460Phase 3

Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer

Completed
NCT02693535Phase 2

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

Recruiting
NCT00600496Phase 1

A Phase I, Open-Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD6244 (ARRY-142886)

Completed
NCT01552434Phase 1

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

Terminated
NCT05773326Early Phase 1

Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG

Terminated
NCT01187199Phase 1

Phase I Trial of Bevacizumab and Temsirolimus in Combination With 1) Carboplatin, 2) Paclitaxel, 3) Sorafenib for the Treatment of Advanced Cancer

Active Not Recruiting
NCT01375829Phase 1

Ixabepilone and Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Active Not Recruiting
NCT01396408Phase 2

A Phase II Study of Sunitinib or Temsirolimus in Patients With Advanced Rare Tumours

Active Not Recruiting
NCT03297606Phase 2

Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR)

Recruiting
NCT02215720Phase 1

Temsirolimus and Cetuximab in Patients With Advanced or Metastatic Solid Tumors

Completed
NCT02389309Phase 1

Dasatinib, Temsirolimus, and Cyclophosphamide in Treating Patients With Advanced, Recurrent, or Refractory Solid Tumors

Active Not Recruiting
NCT01946529Phase 2

Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors

Active Not Recruiting
NCT04199026Not Applicable

Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma

Recruiting
NCT01326468Not Applicable

Torisel in Addition to Standard Chemotherapy With Radiation for Advanced Head and Neck Cancer

Withdrawn
NCT04433572Phase 3

Temsirolimus Adventitial Delivery to Improve ANGioplasty and/or Atherectomy Revascularization Outcomes Below the Knee

Recruiting
NCT02420613Phase 1

Vorinostat and Temsirolimus With or Without Radiation Therapy in Treating Younger Patients With Newly Diagnosed or Progressive Diffuse Intrinsic Pontine Glioma

Completed

Drug Details

Intervention Type
DRUG
Total Trials
169