Success Metrics

Clinical Success Rate
85.8%

Based on 103 completed trials

Completion Rate
86%(103/120)
Active Trials
38(19%)
Results Posted
57%(59 trials)
Terminated
17(9%)

Phase Distribution

Ph phase_4
14
7%
Ph phase_1
20
10%
Ph phase_2
80
40%
Ph not_applicable
11
6%
Ph phase_3
59
30%
Ph early_phase_1
4
2%

Phase Distribution

24

Early Stage

80

Mid Stage

73

Late Stage

Phase Distribution188 total trials
Early Phase 1First-in-human
4(2.1%)
Phase 1Safety & dosage
20(10.6%)
Phase 2Efficacy & side effects
80(42.6%)
Phase 3Large-scale testing
59(31.4%)
Phase 4Post-market surveillance
14(7.4%)
N/ANon-phased studies
11(5.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

84.4%

103 of 122 finished

Non-Completion Rate

15.6%

19 ended early

Currently Active

38

trials recruiting

Total Trials

198

all time

Status Distribution
Active(44)
Completed(103)
Terminated(19)
Other(32)

Detailed Status

Completed103
unknown30
Recruiting22
Terminated17
Active, not recruiting16
Not yet recruiting5

Development Timeline

Analytics

Development Status

Total Trials
198
Active
38
Success Rate
85.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (2.1%)
Phase 120 (10.6%)
Phase 280 (42.6%)
Phase 359 (31.4%)
Phase 414 (7.4%)
N/A11 (5.9%)

Trials by Status

active_not_recruiting168%
terminated179%
not_yet_recruiting53%
completed10352%
suspended21%
unknown3015%
withdrawn21%
enrolling_by_invitation11%
recruiting2211%

Recent Activity

Clinical Trials (198)

Showing 20 of 198 trialsScroll for more
NCT05952557Phase 3

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Active Not Recruiting
NCT05512364Phase 3

Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA)

Recruiting
NCT02206984Phase 2

Endocrine Response in Women With Invasive Lobular Breast Cancer

Completed
NCT06671912Phase 3

Testing Low Dose Tamoxifen for Invasive Breast Cancer, LoTam Trial

Suspended
NCT06195306Phase 2

Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction

Recruiting
NCT02476786Phase 2

Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score

Recruiting
NCT06184750Phase 2

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

Recruiting
NCT06075953Phase 2

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

Recruiting
NCT04174352Early Phase 1

FES Imaging to Optimize Tamoxifen for Metastatic Breast Cancer

Recruiting
NCT05774951Phase 3

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Recruiting
NCT06979596Phase 2

A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)

Recruiting
NCT06942039Early Phase 1

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

Recruiting
NCT06492616Phase 3

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Recruiting
NCT05941520Phase 2

Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

Recruiting
NCT05768139Phase 1

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

Recruiting
NCT06001762Phase 2

TRADE: Dose Escalation Tolerability of Abemaciclib in HR+ HER2- Early Stage Breast Cancer

Active Not Recruiting
NCT02764541Phase 2

Palbociclib and Endocrine Therapy for LObular Breast Cancer Preoperative Study (PELOPS)

Active Not Recruiting
NCT05161195Phase 4

Roll-over Study to Allow Continued Access to Ribociclib

Active Not Recruiting
NCT06440967Phase 3

A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Women With Breast Cancer Who Are Having Hormone Therapy

Active Not Recruiting
NCT05306340Phase 3

A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
198