Success Metrics

Clinical Success Rate
100.0%

Based on 2 completed trials

Completion Rate
100%(2/2)
Active Trials
29(83%)
Results Posted
0%(0 trials)

Phase Distribution

Ph phase_1
10
29%
Ph phase_2
16
46%
Ph phase_3
4
11%
Ph not_applicable
1
3%

Phase Distribution

10

Early Stage

16

Mid Stage

4

Late Stage

Phase Distribution31 total trials
Phase 1Safety & dosage
10(32.3%)
Phase 2Efficacy & side effects
16(51.6%)
Phase 3Large-scale testing
4(12.9%)
N/ANon-phased studies
1(3.2%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

66.7%

2 of 3 finished

Non-Completion Rate

33.3%

1 ended early

Currently Active

29

trials recruiting

Total Trials

35

all time

Status Distribution
Active(30)
Completed(2)
Terminated(1)
Other(2)

Detailed Status

Recruiting19
Active, not recruiting10
Completed2
unknown2
Not yet recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
35
Active
29
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 110 (32.3%)
Phase 216 (51.6%)
Phase 34 (12.9%)
N/A1 (3.2%)

Trials by Status

not_yet_recruiting13%
completed26%
active_not_recruiting1029%
recruiting1954%
withdrawn13%
unknown26%

Recent Activity

Clinical Trials (35)

Showing 20 of 35 trialsScroll for more
NCT06993675Phase 2

Engaging T-cells to Eliminate MRD in Newly Diagnosed Myeloma Optimizing Response With Talquetmab and Teclistamab (ROTATE)

Recruiting
NCT06550895Phase 2

A Study of Ciltacabtagene Autoleucel and Talquetamab for the Treatment of Participants With High-Risk Multiple Myeloma

Active Not Recruiting
NCT05972135Phase 2

Outpatient Administration of Teclistamab or Talquetamab for Multiple Myeloma

Recruiting
NCT07107529Phase 2

Study for Frail Patients With Newly Diagnosed Multiple Myeloma Treated With Daratumumab With Teclistamab or Talquetamab.

Recruiting
NCT04634552Phase 2

A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

Recruiting
NCT05552222Phase 3

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

Recruiting
NCT06577025Phase 2

A Study of Different Sequences of Cilta-cel, Talquetamab in Combination With Daratumumab and Teclistamab in Combination With Daratumumab Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in Participants With Standard-risk Newly Diagnosed Multiple Myeloma

Active Not Recruiting
NCT03399799Phase 1

Dose Escalation Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

Active Not Recruiting
NCT06285318

A Study of Clinical Outcomes in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) Treated With T-cell Redirectors Outside of Clinical Trials

Recruiting
NCT07032714Phase 1

Mezigdomide and Talquetamab in Relapsed and Refractory Multiple Myeloma

Recruiting
NCT06500884Phase 2

A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events

Recruiting
NCT05050097Phase 1

A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma

Active Not Recruiting
NCT05455320Phase 3

A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Multiple Myeloma That Returns After Treatment or is Resistant to Treatment

Active Not Recruiting
NCT05338775Phase 1

A Study of Talquetamab and Teclistamab Each in Combination With a Programmed Cell Death Receptor-1 (PD-1) Inhibitor for the Treatment of Participants With Relapsed or Refractory Multiple Myeloma

Active Not Recruiting
NCT04108195Phase 1

A Study of Subcutaneous Daratumumab Regimens in Combination With Bispecific T Cell Redirection Antibodies for the Treatment of Participants With Multiple Myeloma

Active Not Recruiting
NCT07499323Not Applicable

Talquetamab in Patients With Refractory Generalized Myasthenia Gravis

Not Yet Recruiting
NCT06353022Phase 2

Minimal Residual Disease-based Strategy With T-Cell Redirector After Treatment With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone (D-VRd) in Newly Diagnosed Multiple Myeloma

Active Not Recruiting
NCT06208150Phase 3

A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide

Recruiting
NCT06348108Phase 1

Talquetamab in Combination With Iberdomide and Dexamethasone for Relapsed or Refractory Multiple Myeloma

Recruiting
NCT06066346Phase 2

A Study of Talquetamab for People With Multiple Myeloma Who Have Received BCMA CAR T-Cell Therapy

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
35