Success Metrics

Clinical Success Rate
72.7%

Based on 8 completed trials

Completion Rate
73%(8/11)
Active Trials
0(0%)
Results Posted
125%(10 trials)
Terminated
3(25%)

Phase Distribution

Ph phase_3
4
33%
Ph phase_2
3
25%
Ph phase_1
5
42%

Phase Distribution

5

Early Stage

3

Mid Stage

4

Late Stage

Phase Distribution12 total trials
Phase 1Safety & dosage
5(41.7%)
Phase 2Efficacy & side effects
3(25.0%)
Phase 3Large-scale testing
4(33.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

66.7%

8 of 12 finished

Non-Completion Rate

33.3%

4 ended early

Currently Active

0

trials recruiting

Total Trials

12

all time

Status Distribution
Completed(8)
Terminated(4)

Detailed Status

Completed8
Terminated3
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
12
Active
0
Success Rate
72.7%
Most Advanced
Phase 3

Trials by Phase

Phase 15 (41.7%)
Phase 23 (25.0%)
Phase 34 (33.3%)

Trials by Status

completed867%
withdrawn18%
terminated325%

Recent Activity

0 active trials
Showing 5 of 12
terminatedphase_2

A Study of Soticlestat in Adults and Children With Rare Epilepsies

NCT03635073
terminatedphase_3

A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome

NCT05163314
terminatedphase_3

A Study Evaluating Soticlestat in Participants With Dravet Syndrome or Lennox-Gastaut Syndrome Who Have Been Exposed to Fenfluramine

NCT06422377
completedphase_3

A Study of Soticlestat as an Add-on Therapy in Children and Young Adults With Dravet Syndrome

NCT04940624
completedphase_3

A Study of Soticlestat as an Add-on Therapy in Children, Teenagers, and Adults With Lennox-Gastaut Syndrome

NCT04938427
View all 12 trials

Clinical Trials (12)

Showing 12 of 12 trials
NCT03635073Phase 2

A Study of Soticlestat in Adults and Children With Rare Epilepsies

Terminated
NCT05163314Phase 3

A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome

Terminated
NCT06422377Phase 3

A Study Evaluating Soticlestat in Participants With Dravet Syndrome or Lennox-Gastaut Syndrome Who Have Been Exposed to Fenfluramine

Terminated
NCT04940624Phase 3

A Study of Soticlestat as an Add-on Therapy in Children and Young Adults With Dravet Syndrome

Completed
NCT04938427Phase 3

A Study of Soticlestat as an Add-on Therapy in Children, Teenagers, and Adults With Lennox-Gastaut Syndrome

Completed
NCT05284760Phase 1

A Study of Soticlestat Tablets in Healthy Adults

Completed
NCT05098054Phase 1

A Study of Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver Function

Completed
NCT05098041Phase 1

A Study of Soticlestat and Rifampin in Healthy Adults

Completed
NCT05064449Phase 1

A Study of Soticlestat With Itraconazole and Mefenamic Acid in Healthy Adults

Completed
NCT05309902Phase 1

A Study of Soticlestat in Healthy Adults To Evaluate the Effect on QTc Interval

Withdrawn
NCT03694275Phase 2

A Multicenter, Open-label, Pilot Study of Soticlestat (TAK-935/OV935) in Participants With 15Q Duplication Syndrome (Dup 15q) or Cyclin-Dependent Kinase-Like 5 (CDKL5) Deficiency Disorder (ARCADE STUDY)

Completed
NCT03990649Phase 2

Study of TAK-935 as an Adjunctive Therapy in Adult Participants With Complex Regional Pain Syndrome (CRPS)

Completed

All 12 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
12