Success Metrics

Clinical Success Rate
76.9%

Based on 196 completed trials

Completion Rate
77%(196/255)
Active Trials
30(8%)
Results Posted
56%(110 trials)
Terminated
59(16%)

Phase Distribution

Ph phase_1
123
34%
Ph phase_4
9
2%
Ph phase_3
49
13%
Ph phase_2
153
42%
Ph not_applicable
17
5%

Phase Distribution

123

Early Stage

153

Mid Stage

58

Late Stage

Phase Distribution351 total trials
Phase 1Safety & dosage
123(35.0%)
Phase 2Efficacy & side effects
153(43.6%)
Phase 3Large-scale testing
49(14.0%)
Phase 4Post-market surveillance
9(2.6%)
N/ANon-phased studies
17(4.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.3%

196 of 275 finished

Non-Completion Rate

28.7%

79 ended early

Currently Active

30

trials recruiting

Total Trials

364

all time

Status Distribution
Active(32)
Completed(196)
Terminated(79)
Other(57)

Detailed Status

Completed196
Terminated59
unknown56
Withdrawn20
Recruiting15
Active, not recruiting15

Development Timeline

Analytics

Development Status

Total Trials
364
Active
30
Success Rate
76.9%
Most Advanced
Phase 4

Trials by Phase

Phase 1123 (35.0%)
Phase 2153 (43.6%)
Phase 349 (14.0%)
Phase 49 (2.6%)
N/A17 (4.8%)

Trials by Status

terminated5916%
completed19654%
not_yet_recruiting21%
recruiting154%
active_not_recruiting154%
unknown5615%
withdrawn205%
suspended10%

Recent Activity

Clinical Trials (364)

Showing 20 of 364 trialsScroll for more
NCT07836530Phase 3

Study Comparing BGB-B2033 With Sorafenib or Lenvatinib in Relapsed Hepatocellular Carcinoma

Not Yet Recruiting
NCT03533582Phase 3

Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

Active Not Recruiting
NCT02559778Phase 2

Pediatric Precision Laboratory Advanced Neuroblastoma Therapy

Recruiting
NCT07787429Phase 2

Evaluation of the Safety and Efficacy of Mifamurtide Versus Standard Treatment With Sorafenib in Patients With High-risk Osteosarcoma

Recruiting
NCT04770896Phase 3

A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab

Active Not Recruiting
NCT04039607Phase 3

A Study of Nivolumab in Combination With Ipilimumab in Participants With Advanced Hepatocellular Carcinoma

Completed
NCT01946529Phase 2

Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors

Completed
NCT03298451Phase 3

Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma

Active Not Recruiting
NCT05117957Phase 2

Efficacy and Safety of Sorafenib in Previously Treated Advanced Hepatocellular Carcinoma: SOPT Study

Completed
NCT05669339Phase 2

AD HOC Trial: Artificial Intelligence-Based Drug Dosing In Hepatocellular Carcinoma

Recruiting
NCT01171651Phase 2

A Study of Pexa-Vec (JX-594) Prior to Sorafenib to Treat Unresectable Primary Hepatocellular Carcinoma

Completed
NCT04723004Phase 3

Evaluate the Safety and Efficacy of Toripalimab Combined With Bevacizumab Versus Sorafenib Therapy for HCC

Completed
NCT01871766Phase 2

Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy

Active Not Recruiting
NCT00494182Phase 2

Sorafenib in Combination With Carboplatin and Paclitaxel in Treating Participants With Metastatic or Recurrent Head and Neck Squamous Cell Cancer

Active Not Recruiting
NCT03247088Phase 1

Sorafenib, Busulfan and Fludarabine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant

Active Not Recruiting
NCT02562755Phase 3

Hepatocellular Carcinoma Study Comparing Vaccinia Virus Based Immunotherapy Plus Sorafenib vs Sorafenib Alone

Completed
NCT05468359Phase 1

Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients

Recruiting
NCT03017326Phase 3

Paediatric Hepatic International Tumour Trial

Active Not Recruiting
NCT01840592Phase 2

Sorafenib Plus Doxorubicin in Patients With Advanced Hepatocellular Carcinoma With Disease Progression on Sorafenib

Active Not Recruiting
NCT03164057Phase 2

A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
364