Success Metrics

Clinical Success Rate
76.7%

Based on 194 completed trials

Completion Rate
77%(194/253)
Active Trials
31(9%)
Results Posted
57%(110 trials)
Terminated
59(16%)

Phase Distribution

Ph not_applicable
17
5%
Ph phase_3
48
13%
Ph phase_1
123
34%
Ph phase_2
152
42%
Ph phase_4
9
2%

Phase Distribution

123

Early Stage

152

Mid Stage

57

Late Stage

Phase Distribution349 total trials
Phase 1Safety & dosage
123(35.2%)
Phase 2Efficacy & side effects
152(43.6%)
Phase 3Large-scale testing
48(13.8%)
Phase 4Post-market surveillance
9(2.6%)
N/ANon-phased studies
17(4.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.1%

194 of 273 finished

Non-Completion Rate

28.9%

79 ended early

Currently Active

31

trials recruiting

Total Trials

362

all time

Status Distribution
Active(32)
Completed(194)
Terminated(79)
Other(57)

Detailed Status

Completed194
Terminated59
unknown56
Withdrawn20
Active, not recruiting17
Recruiting14

Development Timeline

Analytics

Development Status

Total Trials
362
Active
31
Success Rate
76.7%
Most Advanced
Phase 4

Trials by Phase

Phase 1123 (35.2%)
Phase 2152 (43.6%)
Phase 348 (13.8%)
Phase 49 (2.6%)
N/A17 (4.9%)

Trials by Status

not_yet_recruiting10%
recruiting144%
suspended10%
active_not_recruiting175%
terminated5916%
withdrawn206%
completed19454%
unknown5615%

Recent Activity

Clinical Trials (362)

Showing 20 of 362 trialsScroll for more
NCT03298451Phase 3

Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma

Active Not Recruiting
NCT05117957Phase 2

Efficacy and Safety of Sorafenib in Previously Treated Advanced Hepatocellular Carcinoma: SOPT Study

Completed
NCT03533582Phase 3

Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

Active Not Recruiting
NCT05669339Phase 2

AD HOC Trial: Artificial Intelligence-Based Drug Dosing In Hepatocellular Carcinoma

Recruiting
NCT01171651Phase 2

A Study of Pexa-Vec (JX-594) Prior to Sorafenib to Treat Unresectable Primary Hepatocellular Carcinoma

Completed
NCT04723004Phase 3

Evaluate the Safety and Efficacy of Toripalimab Combined With Bevacizumab Versus Sorafenib Therapy for HCC

Completed
NCT01871766Phase 2

Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy

Active Not Recruiting
NCT00494182Phase 2

Sorafenib in Combination With Carboplatin and Paclitaxel in Treating Participants With Metastatic or Recurrent Head and Neck Squamous Cell Cancer

Active Not Recruiting
NCT03247088Phase 1

Sorafenib, Busulfan and Fludarabine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant

Active Not Recruiting
NCT02562755Phase 3

Hepatocellular Carcinoma Study Comparing Vaccinia Virus Based Immunotherapy Plus Sorafenib vs Sorafenib Alone

Completed
NCT05468359Phase 1

Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients

Recruiting
NCT04770896Phase 3

A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab

Active Not Recruiting
NCT03017326Phase 3

Paediatric Hepatic International Tumour Trial

Active Not Recruiting
NCT01840592Phase 2

Sorafenib Plus Doxorubicin in Patients With Advanced Hepatocellular Carcinoma With Disease Progression on Sorafenib

Active Not Recruiting
NCT02559778Phase 2

Pediatric Precision Laboratory Advanced Neuroblastoma Therapy

Recruiting
NCT03164057Phase 2

A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia

Active Not Recruiting
NCT01187199Phase 1

Phase I Trial of Bevacizumab and Temsirolimus in Combination With 1) Carboplatin, 2) Paclitaxel, 3) Sorafenib for the Treatment of Advanced Cancer

Active Not Recruiting
NCT03132454Phase 1

Palbociclib and Sorafenib, Decitabine, or Dexamethasone in Treating Patients With Recurrent or Refractory Leukemia

Active Not Recruiting
NCT05068752Phase 2

Phase II Trial of Vemurafenib and Sorafenib in Pancreatic Cancer

Completed
NCT02298348Phase 1

Sorafenib and Cyclophosphamide/Topotecan in Patients With Relapsed and Refractory Neuroblastoma

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
362