Success Metrics

Clinical Success Rate
76.5%

Based on 192 completed trials

Completion Rate
76%(192/251)
Active Trials
31(9%)
Results Posted
57%(109 trials)
Terminated
59(16%)

Phase Distribution

Ph phase_3
48
13%
Ph not_applicable
17
5%
Ph phase_4
9
2%
Ph phase_2
151
42%
Ph phase_1
123
34%

Phase Distribution

123

Early Stage

151

Mid Stage

57

Late Stage

Phase Distribution348 total trials
Phase 1Safety & dosage
123(35.3%)
Phase 2Efficacy & side effects
151(43.4%)
Phase 3Large-scale testing
48(13.8%)
Phase 4Post-market surveillance
9(2.6%)
N/ANon-phased studies
17(4.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

70.8%

192 of 271 finished

Non-Completion Rate

29.2%

79 ended early

Currently Active

31

trials recruiting

Total Trials

361

all time

Status Distribution
Active(32)
Completed(192)
Terminated(79)
Other(58)

Detailed Status

Completed192
Terminated59
unknown57
Withdrawn20
Active, not recruiting17
Recruiting14

Development Timeline

Analytics

Development Status

Total Trials
361
Active
31
Success Rate
76.5%
Most Advanced
Phase 4

Trials by Phase

Phase 1123 (35.3%)
Phase 2151 (43.4%)
Phase 348 (13.8%)
Phase 49 (2.6%)
N/A17 (4.9%)

Trials by Status

not_yet_recruiting10%
suspended10%
recruiting144%
active_not_recruiting175%
terminated5916%
withdrawn206%
completed19253%
unknown5716%

Recent Activity

Clinical Trials (361)

Showing 20 of 361 trialsScroll for more
NCT01840592Phase 2

Sorafenib Plus Doxorubicin in Patients With Advanced Hepatocellular Carcinoma With Disease Progression on Sorafenib

Active Not Recruiting
NCT02559778Phase 2

Pediatric Precision Laboratory Advanced Neuroblastoma Therapy

Recruiting
NCT01871766Phase 2

Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy

Active Not Recruiting
NCT03164057Phase 2

A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia

Active Not Recruiting
NCT01187199Phase 1

Phase I Trial of Bevacizumab and Temsirolimus in Combination With 1) Carboplatin, 2) Paclitaxel, 3) Sorafenib for the Treatment of Advanced Cancer

Active Not Recruiting
NCT03132454Phase 1

Palbociclib and Sorafenib, Decitabine, or Dexamethasone in Treating Patients With Recurrent or Refractory Leukemia

Active Not Recruiting
NCT05068752Phase 2

Phase II Trial of Vemurafenib and Sorafenib in Pancreatic Cancer

Completed
NCT02298348Phase 1

Sorafenib and Cyclophosphamide/Topotecan in Patients With Relapsed and Refractory Neuroblastoma

Active Not Recruiting
NCT03298451Phase 3

Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma

Active Not Recruiting
NCT07463651Phase 3

MRD-guided Maintenance Post-HCT: Gilteritini vs Sorafenib

Recruiting
NCT04720716Phase 3

A Study to Compare the Effectiveness and Safety of IBI310 Combined With Sintilimab Versus Sorafenib in the First-line Treatment of Advanced HCC

Completed
NCT05468359Phase 1

Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients

Recruiting
NCT01946529Phase 2

Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors

Active Not Recruiting
NCT04039607Phase 3

A Study of Nivolumab in Combination With Ipilimumab in Participants With Advanced Hepatocellular Carcinoma

Active Not Recruiting
NCT05669339Phase 2

AD HOC Trial: Artificial Intelligence-Based Drug Dosing In Hepatocellular Carcinoma

Recruiting
NCT04770896Phase 3

A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab

Active Not Recruiting
NCT06227221Phase 2

Efficacy and Safety of Sorafenib in New-Onset Type 1 Diabetes Mellitus

Not Yet Recruiting
NCT02143726Phase 2

Sorafenib Tosylate With or Without Everolimus in Treating Patients With Advanced, Radioactive Iodine Refractory Hurthle Cell Thyroid Cancer

Active Not Recruiting
NCT01903694Phase 3

Randomized Trial Sorafenib-Pravastatin Versus Sorafenib Alone for the Palliative Treatment of Child-Pugh A Hepatocellular Carcinoma

Completed
NCT01730937Phase 3

Sorafenib Tosylate With or Without Stereotactic Body Radiation Therapy in Treating Patients With Liver Cancer

Completed

Drug Details

Intervention Type
DRUG
Total Trials
361