Success Metrics

Clinical Success Rate
100.0%

Based on 2 completed trials

Completion Rate
100%(2/2)
Active Trials
21(66%)
Results Posted
50%(1 trials)

Phase Distribution

Ph phase_3
5
16%
Ph phase_2
15
47%
Ph phase_1
12
38%

Phase Distribution

12

Early Stage

15

Mid Stage

5

Late Stage

Phase Distribution32 total trials
Phase 1Safety & dosage
12(37.5%)
Phase 2Efficacy & side effects
15(46.9%)
Phase 3Large-scale testing
5(15.6%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

100.0%

2 of 2 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

21

trials recruiting

Total Trials

32

all time

Status Distribution
Active(30)
Completed(2)

Detailed Status

Recruiting15
Not yet recruiting9
Active, not recruiting6
Completed2

Development Timeline

Analytics

Development Status

Total Trials
32
Active
21
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 112 (37.5%)
Phase 215 (46.9%)
Phase 35 (15.6%)

Trials by Status

not_yet_recruiting928%
active_not_recruiting619%
completed26%
recruiting1547%

Recent Activity

Clinical Trials (32)

Showing 20 of 32 trialsScroll for more
NCT07855991Phase 1

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Sonrotoclax in Participants With Severe Hepatic Impairment

Not Yet Recruiting
NCT07321652Phase 3

Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL

Recruiting
NCT07277231Phase 3

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

Recruiting
NCT04973605Phase 1

A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma

Recruiting
NCT06742996Phase 3

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

Recruiting
NCT06073821Phase 3

Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)

Active Not Recruiting
NCT06697184Phase 1

A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.

Recruiting
NCT06943872Phase 3

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

Recruiting
NCT05471843Phase 1

Study of Sonrotoclax (BGB-11417) Monotherapy in Participants With Relapsed or Refractory Mantle Cell Lymphoma

Active Not Recruiting
NCT07341191Phase 2

Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma Planned for Standard of Care CAR-T Cell Therapy

Recruiting
NCT06634589Phase 1

A Study to Investigate Safety and Effectiveness of Tacabrutideg (BGB-16673) in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

Recruiting
NCT07799220Phase 2

A Study of Zanubrutinib, Obinutuzumab, and Sonrotoclax in People With Mantle Cell Lymphoma

Not Yet Recruiting
NCT07812246Phase 2

Zanubrutinib and Sonrotoclax for the Treatment of Relapsed Chronic Lymphocytic Leukemia /Small Lymphocytic Leukemia, ZeuS-2 Trial

Not Yet Recruiting
NCT04271956Phase 2

Efficacy and Safety of Zanubrutinib Plus Tislelizumab Treatment With or Without Sonrotoclax for Patients With Richter Transformation

Recruiting
NCT07774234Phase 2

Sonrotoclax, Glofitamab, Gemcitabine, and Oxaliplatin for Relapsed or Refractory Large B-Cell Lymphoma

Not Yet Recruiting
NCT07770698Phase 1

A Study of Sonrotoclax (BGB-11417) in Children With Relapsed or Refractory Acute Myeloid Leukemia and B-cell Acute Lymphoblastic Leukemia

Not Yet Recruiting
NCT06849713Phase 2

Zanubrutinib, Obinutuzumab, Sonrotoclax (BOSon) or BGB-16673, Obinutuzumab, Sonrotoclax (DOSon) in TN CLL/SLL

Recruiting
NCT07548710Phase 2

Study of SA+X in the Treatment of Newly Diagnosed AML

Recruiting
NCT07335887Phase 2

Sonrotoclax Plus Dexamethasone With or Without Daratumumab Regimen in Patients With t(11;14) Primary AL Amyloidosis

Recruiting
NCT06637501Phase 2

A Study to Investigate Sonrotoclax Combined With Zanubrutinib Versus Zanubrutinib Alone in Participants With Previously Untreated Chronic Lymphocytic Leukemia

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
32