Success Metrics

Clinical Success Rate
63.6%

Based on 7 completed trials

Completion Rate
64%(7/11)
Active Trials
4(27%)
Results Posted
143%(10 trials)
Terminated
4(27%)

Phase Distribution

Ph phase_2
3
20%
Ph phase_1
1
7%
Ph phase_3
8
53%
Ph phase_4
3
20%

Phase Distribution

1

Early Stage

3

Mid Stage

11

Late Stage

Phase Distribution15 total trials
Phase 1Safety & dosage
1(6.7%)
Phase 2Efficacy & side effects
3(20.0%)
Phase 3Large-scale testing
8(53.3%)
Phase 4Post-market surveillance
3(20.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

63.6%

7 of 11 finished

Non-Completion Rate

36.4%

4 ended early

Currently Active

4

trials recruiting

Total Trials

15

all time

Status Distribution
Active(4)
Completed(7)
Terminated(4)

Detailed Status

Completed7
Terminated4
Recruiting3
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
15
Active
4
Success Rate
63.6%
Most Advanced
Phase 4

Trials by Phase

Phase 11 (6.7%)
Phase 23 (20.0%)
Phase 38 (53.3%)
Phase 43 (20.0%)

Trials by Status

active_not_recruiting17%
terminated427%
completed747%
recruiting320%

Recent Activity

Clinical Trials (15)

Showing 15 of 15 trials
NCT04585542Phase 4

Comparison of Potassium Binders in the ER

Terminated
NCT06578078Phase 3

A Clinical Trial to Define the Best Strategy for the Management of Heart Failure in Elderly Patients

Recruiting
NCT04676646Phase 4

Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving Spironolactone

Completed
NCT04789239Phase 2

OPtimizing Aldosterone Receptor Antagonist Therapy by Sodium Zirconium Cyclosilicate in Heart Failure

Active Not Recruiting
NCT04983979Phase 2

The ORTIZ Study: Optimising RASi Therapy With SZC

Terminated
NCT06365684Phase 4

Sodium Zirconium Cyclosilicate to Allow Liberal Fruit and Vegetable Intake for Patients With CKD Stage 3b and 4

Recruiting
NCT06578533Phase 3

Keeping RAASi Treatment With Optimal Potassium Control

Recruiting
NCT04788641Phase 1

Study to Assess the Effect of Sodium Zirconium Cyclosilicate on the Pharmacokinetics of Tacrolimus and Cyclosporin in Healthy Subjects

Completed
NCT04727528Phase 3

Study of the Effect of SZC on Serum Potassium and Serum Bicarbonate in Patients With Hyperkalemia and Metabolic Acidosis Associated With Chronic Kidney Disease

Terminated
NCT04217590Phase 3

Reduce Incidence of Pre-Dialysis Hyperkalaemia With Sodium Zirconium Cyclosilicate in Chinese Subjects

Completed
NCT05382988Phase 3

Sodium Zirconium Cyclosilicate Lowers Hyperkalemia After Parathyroidectomy

Completed
NCT03532009Phase 2

Potassium Reduction Initiative to Optimize RAAS Inhibition Therapy With Sodium Zirconium Cyclosilicate in Heart Failure

Terminated
NCT02088073Phase 3

Safety & Efficacy of Zirconium Silicate Dosed for 28 Days in Hyperkalemia.

Completed
NCT02107092Phase 3

Open-label Safety & Efficacy of ZS (Sodium Zirconium Cyclosilicate)10g qd to Extend Study ZS-004 in Hyperkalemia.

Completed
NCT02163499Phase 3

Open-label Safety and Efficacy of Sodium Zirconium Cyclosilicate for up to 12 Months

Completed

All 15 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
15