Success Metrics

Clinical Success Rate
81.0%

Based on 17 completed trials

Completion Rate
81%(17/21)
Active Trials
0(0%)
Results Posted
71%(12 trials)
Terminated
4(14%)

Phase Distribution

Ph phase_1
11
39%
Ph not_applicable
1
4%
Ph phase_2
15
54%
Ph phase_3
1
4%

Phase Distribution

11

Early Stage

15

Mid Stage

1

Late Stage

Phase Distribution28 total trials
Phase 1Safety & dosage
11(39.3%)
Phase 2Efficacy & side effects
15(53.6%)
Phase 3Large-scale testing
1(3.6%)
N/ANon-phased studies
1(3.6%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

70.8%

17 of 24 finished

Non-Completion Rate

29.2%

7 ended early

Currently Active

0

trials recruiting

Total Trials

28

all time

Status Distribution
Completed(17)
Terminated(7)
Other(4)

Detailed Status

Completed17
Terminated4
unknown4
Withdrawn3

Development Timeline

Analytics

Development Status

Total Trials
28
Active
0
Success Rate
81.0%
Most Advanced
Phase 3

Trials by Phase

Phase 111 (39.3%)
Phase 215 (53.6%)
Phase 31 (3.6%)
N/A1 (3.6%)

Trials by Status

completed1761%
terminated414%
withdrawn311%
unknown414%

Recent Activity

0 active trials
Showing 5 of 28
terminatedphase_1

Inhaled Sodium Nitrite as an Antimicrobial for Cystic Fibrosis

NCT02694393
completedphase_2

Oral Nitrite in Patients With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction

NCT03015402
completedphase_2

Inorganic Nitrite to Amplify the Benefits and Tolerability of Exercise Training in Heart Failure With Preserved Ejection Fraction (HFpEF) (INABLE-Training)

NCT02713126
completedphase_2

The Effects of NOx and Conjugated Linoleic Acid on Asthmatics

NCT02433977
withdrawnphase_1

Nitrite Infusion in Children With Malaria

NCT04289558
View all 28 trials

Clinical Trials (28)

Showing 20 of 28 trialsScroll for more
NCT02694393Phase 1

Inhaled Sodium Nitrite as an Antimicrobial for Cystic Fibrosis

Terminated
NCT03015402Phase 2

Oral Nitrite in Patients With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction

Completed
NCT02713126Phase 2

Inorganic Nitrite to Amplify the Benefits and Tolerability of Exercise Training in Heart Failure With Preserved Ejection Fraction (HFpEF) (INABLE-Training)

Completed
NCT02433977Phase 2

The Effects of NOx and Conjugated Linoleic Acid on Asthmatics

Completed
NCT04289558Phase 1

Nitrite Infusion in Children With Malaria

Withdrawn
NCT04401527Phase 2

Treatment of Lung Injury From COVID-19 Infection With Intravenous Sodium Nitrite

Withdrawn
NCT00873015Phase 2

Safety and Pharmacokinetic Evaluation of Nitrite for Prevention of Cerebral Vasospasm

Completed
NCT02412852Phase 2

A Phase 2a Study to Assess Safety & Pharmacokinetics of Sustained Release Sodium Nitrite in Patients With Diabetic Pain

Completed
NCT01401517Phase 2

Phase IIa: Safety, PK, & Tolerability of Sodium Nitrite in Patients With Peripheral Arterial Disease-SONIC

Completed
NCT04354051Phase 1

The Nitrite and Coronary Flow Study

Completed
NCT02918552Phase 2

Oral Nitrite for Older Heart Failure With Preserved Ejection Fraction

Completed
NCT02393742Not Applicable

Nitrite Supplementation for Improving Physiological Function in Older Adults

Completed
NCT00095472Phase 1

Therapeutic Application of Intravascular Nitrite for Sickle Cell Disease

Completed
NCT04001283Phase 2

Nitrite Effects on Cardiac Muscle in CABG

Unknown
NCT03331146Phase 3

Nitrite Infusion in High Risk Patients Undergoing Cardiopulmonary Bypass

Withdrawn
NCT01715883Phase 2

Sodium Nitrite in Lung Transplant Patients to Minimize the Risk of Pulmonary Graft Dysfunction

Terminated
NCT00105222Phase 1

Effect of Nitrite on Exercise Physiology and Metabolism

Terminated
NCT00924118Phase 2

Sodium Nitrite in Acute Myocardial Infarction

Completed
NCT02987088Phase 1

Phase 1 Clinical Trial of Sodium Nitrite for Out of Hospital Cardiac Arrest

Completed
NCT02176837Phase 2

Intravenous Nitrite Infusion for Reversal of Cerebral Vasospasm After Subarachnoid Hemorrhage

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
28