Success Metrics

Clinical Success Rate
79.6%

Based on 199 completed trials

Completion Rate
80%(199/250)
Active Trials
72(19%)
Results Posted
67%(133 trials)
Terminated
51(13%)

Phase Distribution

Ph phase_4
47
12%
Ph early_phase_1
9
2%
Ph phase_1
125
33%
Ph not_applicable
20
5%
Ph phase_2
144
38%
Ph phase_3
29
8%

Phase Distribution

134

Early Stage

144

Mid Stage

76

Late Stage

Phase Distribution374 total trials
Early Phase 1First-in-human
9(2.4%)
Phase 1Safety & dosage
125(33.4%)
Phase 2Efficacy & side effects
144(38.5%)
Phase 3Large-scale testing
29(7.8%)
Phase 4Post-market surveillance
47(12.6%)
N/ANon-phased studies
20(5.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

74.0%

199 of 269 finished

Non-Completion Rate

26.0%

70 ended early

Currently Active

72

trials recruiting

Total Trials

384

all time

Status Distribution
Active(83)
Completed(199)
Terminated(70)
Other(32)

Detailed Status

Completed199
Terminated51
Recruiting42
Active, not recruiting30
unknown30
Withdrawn19

Development Timeline

Analytics

Development Status

Total Trials
384
Active
72
Success Rate
79.6%
Most Advanced
Phase 4

Trials by Phase

Early Phase 19 (2.4%)
Phase 1125 (33.4%)
Phase 2144 (38.5%)
Phase 329 (7.8%)
Phase 447 (12.6%)
N/A20 (5.3%)

Trials by Status

completed19952%
terminated5113%
not_yet_recruiting82%
recruiting4211%
withdrawn195%
active_not_recruiting308%
unknown308%
enrolling_by_invitation31%
suspended21%

Recent Activity

Clinical Trials (384)

Showing 20 of 384 trialsScroll for more
NCT06876142Phase 1

Combination Therapy (Mirdametinib and Sirolimus) for RAS Mutated Relapsed Refractory Multiple Myeloma

Suspended
NCT06261060Phase 2

Low-Dose Sirolimus to Increase Hematopoietic Function in Patients With RUNX1 Familial Platelet Disorder

Recruiting
NCT07052929Phase 1

Study of ASP2957 in Male Participants With X-linked Myotubular Myopathy Who Need Ventilators

Recruiting
NCT04177004Phase 1

Human Lysozyme Goat Milk for the Prevention of Graft Versus Host Disease in Patients With Blood Cancer Undergoing a Donor Stem Cell Transplant

Suspended
NCT00092222Phase 2

Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity

Active Not Recruiting
NCT00811915Phase 3

Study to Compare the Safety and Efficacy of Sirolimus (Rapamune) to Tacrolimus (Advagraf) Associated to Mycophenolate Mofetil (CellCept) Between 12 and 36 Months After Kidney Transplantation

Terminated
NCT03192397Phase 1

Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

Active Not Recruiting
NCT05896839Phase 1

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

Recruiting
NCT00792948Phase 2

Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT02711202Not Applicable

Sequential Targeting of Cluster of Differentiation 52 (CD52) and Tumor Necrosis Factor (TNF) Allows Early Minimization Therapy in Kidney Transplantation

Completed
NCT04959175Phase 1

Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

Recruiting
NCT06084780Phase 2

Intestinal & Multivisceral Transplantation for Unresectable Mucinous Carcinoma Peritonei (TRANSCAPE)

Not Yet Recruiting
NCT05088356Phase 1

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

Recruiting
NCT03605927Phase 1

CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease

Completed
NCT02891603Phase 1

A Phase I/II GVHD Prevention Trial Combining Pacritinib With Sirolimus-Based Immune Suppression

Completed
NCT04411654Phase 1

Phase 1/2 Clinical Trial of PR001 in Infants With Type 2 Gaucher Disease (PROVIDE)

Active Not Recruiting
NCT02629120Phase 1

High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant Cyclophosphamide for Patients With Chronic Granulomatous Disease

Active Not Recruiting
NCT05463133Phase 1

Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) Antagonists

Recruiting
NCT06325709Phase 1

Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease

Recruiting
NCT00001247

Inpatient Evaluation of Adults With Schizophrenia

Completed

Drug Details

Intervention Type
DRUG
Total Trials
384