Success Metrics

Clinical Success Rate
83.4%

Based on 131 completed trials

Completion Rate
83%(131/157)
Active Trials
11(6%)
Results Posted
48%(63 trials)
Terminated
26(14%)

Phase Distribution

Ph phase_3
32
17%
Ph phase_4
65
34%
Ph phase_2
36
19%
Ph not_applicable
27
14%
Ph early_phase_1
1
1%
Ph phase_1
17
9%

Phase Distribution

18

Early Stage

36

Mid Stage

97

Late Stage

Phase Distribution178 total trials
Early Phase 1First-in-human
1(0.6%)
Phase 1Safety & dosage
17(9.6%)
Phase 2Efficacy & side effects
36(20.2%)
Phase 3Large-scale testing
32(18.0%)
Phase 4Post-market surveillance
65(36.5%)
N/ANon-phased studies
27(15.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

80.9%

131 of 162 finished

Non-Completion Rate

19.1%

31 ended early

Currently Active

11

trials recruiting

Total Trials

189

all time

Status Distribution
Active(13)
Completed(131)
Terminated(31)
Other(14)

Detailed Status

Completed131
Terminated26
unknown14
Recruiting10
Withdrawn5
Not yet recruiting2

Development Timeline

Analytics

Development Status

Total Trials
189
Active
11
Success Rate
83.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.6%)
Phase 117 (9.6%)
Phase 236 (20.2%)
Phase 332 (18.0%)
Phase 465 (36.5%)
N/A27 (15.2%)

Trials by Status

active_not_recruiting11%
not_yet_recruiting21%
unknown147%
completed13169%
withdrawn53%
terminated2614%
recruiting105%

Recent Activity

Clinical Trials (189)

Showing 20 of 189 trialsScroll for more
NCT05892744Phase 4

Establishing Multimodal Brain Biomarkers for Treatment Selection in Depression

Recruiting
NCT03511118

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

Recruiting
NCT06408246Phase 2

ACE-D Aim 3 Clinical Cognitive Trial to Enhance Translation in Depression

Recruiting
NCT04183205Phase 4

Predicting SSRI Efficacy in Veterans With PTSD

Terminated
NCT05814640Phase 1

Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD)

Recruiting
NCT05603104Phase 3

Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure

Recruiting
NCT00262470Phase 1

Treatment of Orthostatic Intolerance

Active Not Recruiting
NCT05973786Phase 3

The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.

Recruiting
NCT05537584Phase 4

SMART Trial to Predict Anhedonia Response to Antidepressant Treatment

Completed
NCT06081348Phase 2

Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders

Recruiting
NCT02813447Not Applicable

Safety of Anti-Depressant for Chronic Obstructive Pulmonary Disease (SAD-COPD)

Terminated
NCT04124614Phase 3

Brexpiprazole as Combination Therapy With Sertraline in Treatment of Adults With PTSD

Completed
NCT02777372Phase 4

Stress & Premenstrual Symptoms Study

Completed
NCT07011693Phase 4

Switching Medication and Augmentation Strategies for SSRI-Resistant Adolescent Depression(SMART-I)

Not Yet Recruiting
NCT04174170Phase 3

Brexpiprazole as Combination Therapy With Sertraline in the Treatment of Adults With Post-traumatic Stress Disorder

Completed
NCT03852160Phase 3

A Study of Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant in Adult and Elderly Participants With Treatment-resistant Depression

Withdrawn
NCT04637620Phase 2

NMDA Modulation in Major Depressive Disorder

Recruiting
NCT05683223Not Applicable

Neural Markers of Treatment Mechanisms and Prediction of Treatment Outcomes in Social Anxiety

Recruiting
NCT06827431Phase 3

The Research of Ammoxetine Hydrochloride Enteric-coated Tablets in Subjects With Depression

Not Yet Recruiting
NCT04446039

Non-interventional, Retrospective Cohort Study to Explore Antidepressant Treatment in Korea

Completed

Drug Details

Intervention Type
DRUG
Total Trials
189