Success Metrics

Clinical Success Rate
90.0%

Based on 217 completed trials

Completion Rate
90%(217/241)
Active Trials
21(7%)
Results Posted
33%(72 trials)
Terminated
24(8%)

Phase Distribution

Ph early_phase_1
1
0%
Ph phase_3
27
9%
Ph not_applicable
9
3%
Ph phase_1
93
32%
Ph phase_2
160
55%
Ph phase_4
1
0%

Phase Distribution

94

Early Stage

160

Mid Stage

28

Late Stage

Phase Distribution291 total trials
Early Phase 1First-in-human
1(0.3%)
Phase 1Safety & dosage
93(32.0%)
Phase 2Efficacy & side effects
160(55.0%)
Phase 3Large-scale testing
27(9.3%)
Phase 4Post-market surveillance
1(0.3%)
N/ANon-phased studies
9(3.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

87.1%

217 of 249 finished

Non-Completion Rate

12.9%

32 ended early

Currently Active

21

trials recruiting

Total Trials

291

all time

Status Distribution
Active(23)
Completed(217)
Terminated(32)
Other(19)

Detailed Status

Completed217
Terminated24
unknown17
Active, not recruiting11
Recruiting10
Withdrawn8

Development Timeline

Analytics

Development Status

Total Trials
291
Active
21
Success Rate
90.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.3%)
Phase 193 (32.0%)
Phase 2160 (55.0%)
Phase 327 (9.3%)
Phase 41 (0.3%)
N/A9 (3.1%)

Trials by Status

active_not_recruiting114%
terminated248%
suspended21%
unknown176%
withdrawn83%
recruiting103%
completed21775%
not_yet_recruiting21%

Recent Activity

Clinical Trials (291)

Showing 20 of 291 trialsScroll for more
NCT04237623Phase 2

GM-CSF With Post-Transplant Cyclophosphamide

Recruiting
NCT07437963Phase 1

Testing the Addition of Iberdomide to Therapy in People With Neuroblastoma That Has Come Back, Not Responded to Treatment, or Gotten Worse

Not Yet Recruiting
NCT03786783Phase 2

Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

Active Not Recruiting
NCT02339571Phase 2

A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma

Active Not Recruiting
NCT07169617Phase 2

Testing the SurVaxM Vaccine for Lung Cancer Prevention

Not Yet Recruiting
NCT02455557Phase 2

SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Active Not Recruiting
NCT05269381Phase 1

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Recruiting
NCT07078604Phase 2

A Cancer Vaccine (STEMVAC) in Combination With Chemotherapy for the Treatment of PD-L1 Negative Metastatic Triple-Negative Breast Cancer

Recruiting
NCT06202066Phase 2

Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Carcinomas

Recruiting
NCT00026312Phase 3

Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma

Completed
NCT03126916Phase 3

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Recruiting
NCT03794349Phase 2

Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma

Active Not Recruiting
NCT07085338Phase 2

A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma

Recruiting
NCT06528496Phase 2

N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma

Recruiting
NCT03879694Phase 1

Survivin Long Peptide Vaccine in Treating Patients With Metastatic Neuroendocrine Tumors

Completed
NCT01391962Phase 2

Sunitinib or Cediranib for Alveolar Soft Part Sarcoma

Completed
NCT04902703Phase 2

Phase II Trial to Evaluate Safety and Efficacy of GM-CSF/Sargramostim in Alzheimer's Disease

Recruiting
NCT03790670Phase 1

Biomarker Assessments of Leukine During Treatment of Parkinson's Disease

Completed
NCT01134614Phase 2

Ipilimumab With or Without Sargramostim in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

Active Not Recruiting
NCT05677633Phase 1

Biomarker Validation Following Sargramostim Treatment in Parkinson's Disease

Completed

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
291