Success Metrics

Clinical Success Rate
100.0%

Based on 9 completed trials

Completion Rate
100%(9/9)
Active Trials
9(47%)
Results Posted
67%(6 trials)

Phase Distribution

Ph phase_1
5
26%
Ph phase_2
7
37%
Ph phase_4
4
21%

Phase Distribution

5

Early Stage

7

Mid Stage

4

Late Stage

Phase Distribution16 total trials
Phase 1Safety & dosage
5(31.3%)
Phase 2Efficacy & side effects
7(43.8%)
Phase 4Post-market surveillance
4(25.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

100.0%

9 of 9 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

9

trials recruiting

Total Trials

19

all time

Status Distribution
Active(9)
Completed(9)
Other(1)

Detailed Status

Completed9
Recruiting5
Active, not recruiting4
unknown1

Development Timeline

Analytics

Development Status

Total Trials
19
Active
9
Success Rate
100.0%
Most Advanced
Phase 4

Trials by Phase

Phase 15 (31.3%)
Phase 27 (43.8%)
Phase 44 (25.0%)

Trials by Status

unknown15%
completed947%
active_not_recruiting421%
recruiting526%

Recent Activity

Clinical Trials (19)

Showing 19 of 19 trials
NCT05861986Phase 4

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy

Recruiting
NCT05808764Phase 2

A Study to Investigate the Pharmacokinetics and Safety of Risdiplam in Infants With Spinal Muscular Atrophy

Recruiting
NCT07047144Phase 2

A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy

Recruiting
NCT05232929Phase 4

Long-term Follow-up Study of Risdiplam in Participants With Spinal Muscular Atrophy (SMA)

Active Not Recruiting
NCT05861999Phase 4

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy

Recruiting
NCT03779334Phase 2

A Study of Risdiplam in Infants With Genetically Diagnosed and Presymptomatic Spinal Muscular Atrophy

Active Not Recruiting
NCT05115110Phase 2

A Study to Investigate the Safety and Efficacy of RO7204239 in Combination With Risdiplam (RO7034067) in Participants With Spinal Muscular Atrophy

Active Not Recruiting
NCT05219487

Investigating NMJ Defects in SMA Following Central and Peripheral SMN Restoration

Completed
NCT03032172Phase 2

A Study of Risdiplam (RO7034067) in Adult and Pediatric Participants With Spinal Muscular Atrophy

Completed
NCT06978985

Adult SMA Research and Clinical Hub

Recruiting
NCT02913482Phase 2

Investigate Safety, Tolerability, PK, PD and Efficacy of Risdiplam (RO7034067) in Infants With Type1 Spinal Muscular Atrophy

Completed
NCT02908685Phase 2

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of Risdiplam (RO7034067) in Type 2 and 3 Spinal Muscular Atrophy (SMA) Participants

Completed
NCT05522361Phase 4

Risdiplam in Patients With Spinal Muscular Atrophy Previously Treated With Nusinersen

Active Not Recruiting
NCT04718181Phase 1

Bioavailability and Bioequivalence of Two Risdiplam Tablets in Healthy Participants

Completed
NCT03920865Phase 1

A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics and Safety and Tolerability of a Single Oral Dose of Risdiplam Compared to Matched Healthy Participants With Normal Hepatic Function

Completed
NCT03988907Phase 1

A Drug-drug Interaction Study With Risdiplam Multiple Dose and Midazolam in Healthy Participants

Completed
NCT04256265

An Expanded Access Program for Risdiplam in Participants With Spinal Muscular Atrophy (SMA)

Unknown
NCT03040635Phase 1

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Risdiplam (RO7034067) in Healthy Japanese Participants

Completed
NCT02633709Phase 1

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Risdiplam (RO7034067) Given by Mouth in Healthy Volunteers

Completed

All 19 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
19