Success Metrics

Clinical Success Rate
12.5%

Based on 1 completed trials

Completion Rate
13%(1/8)
Active Trials
9(41%)
Results Posted
600%(6 trials)
Terminated
7(32%)

Phase Distribution

Ph phase_1
20
91%
Ph phase_2
1
5%

Phase Distribution

20

Early Stage

1

Mid Stage

0

Late Stage

Phase Distribution21 total trials
Phase 1Safety & dosage
20(95.2%)
Phase 2Efficacy & side effects
1(4.8%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

10.0%

1 of 10 finished

Non-Completion Rate

90.0%

9 ended early

Currently Active

9

trials recruiting

Total Trials

22

all time

Status Distribution
Active(11)
Completed(1)
Terminated(9)
Other(1)

Detailed Status

Active, not recruiting7
Terminated7
Not yet recruiting2
Recruiting2
Withdrawn2
unknown1

Development Timeline

Analytics

Development Status

Total Trials
22
Active
9
Success Rate
12.5%
Most Advanced
Phase 2

Trials by Phase

Phase 120 (95.2%)
Phase 21 (4.8%)

Trials by Status

unknown15%
active_not_recruiting732%
not_yet_recruiting29%
recruiting29%
terminated732%
withdrawn29%
completed15%

Recent Activity

Clinical Trials (22)

Showing 20 of 22 trialsScroll for more
NCT07553390Phase 1

Phase 1b Study Of TRICK-NK In Combination With T-Dxd In Treatment-Refractory Breast Cancers

Not Yet Recruiting
NCT04960579Phase 1

P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Multiple Myeloma

Active Not Recruiting
NCT06984341Phase 1

A Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Pharmacodynamics, and Efficacy of P-CD19CD20-ALLO1 in Participants With Severe, Treatment-refractory Systemic Lupus Erythematosus (SLE)

Not Yet Recruiting
NCT06066424Phase 1

Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)

Recruiting
NCT06014762Phase 1

P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies

Recruiting
NCT02744287Phase 1

Safety and Activity Study of PSCA-Targeted CAR-T Cells (BPX-601) in Subjects With Selected Advanced Solid Tumors

Terminated
NCT05239143Phase 1

P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors

Active Not Recruiting
NCT03016377Phase 1

Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL

Active Not Recruiting
NCT04249947Phase 1

P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)

Terminated
NCT03288493Phase 1

P-BCMA-101 Tscm CAR-T Cells in the Treatment of Patients With Multiple Myeloma (MM)

Terminated
NCT02743611Phase 1

Safety & Activity of Controllable PRAME-TCR Therapy in Previously Treated AML/MDS or Metastatic Uveal Melanoma

Terminated
NCT02065869Phase 1

Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant

Terminated
NCT03699475Phase 2

Study of Haplo-HSCT + Rivogenlecleucel vs Haplo-HSCT + Post Transplant Cyclophosphamide in Patients With AML or MDS

Terminated
NCT03733249Phase 1

Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study

Terminated
NCT02477878Phase 1

Study of Gene Modified Donor T Cell Infusion in Patients With Recurrent Disease After Allogeneic Transplant

Active Not Recruiting
NCT03459170Phase 1

Safety/PK Study of Gene Modified Donor T Cell Infusion in Children With Recurrent Hem Malignancies After Allo Transplant

Active Not Recruiting
NCT03301168Phase 1

Study of Gene Modified Donor T-cells Following TCR Alpha Beta Positive Depleted Stem Cell Transplant

Active Not Recruiting
NCT01744223Phase 1

Safety Study of Gene Modified Donor T-cells Following Partially Mismatched Stem Cell Transplant

Active Not Recruiting
NCT03958656Phase 1

T-cells Expressing an Anti-SLAMF7 CAR for Treating Multiple Myeloma

Completed
NCT03639844

BPX-501 T Cells Infused Post Stem Cell Transplant in Pediatrics With Non-Malignant Disorders Ineligible for BPU004 Study

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
22