Success Metrics

Clinical Success Rate
87.5%

Based on 7 completed trials

Completion Rate
88%(7/8)
Active Trials
8(50%)
Results Posted
43%(3 trials)
Terminated
1(6%)

Phase Distribution

Ph phase_1
2
13%
Ph phase_2
7
44%
Ph phase_3
7
44%

Phase Distribution

2

Early Stage

7

Mid Stage

7

Late Stage

Phase Distribution16 total trials
Phase 1Safety & dosage
2(12.5%)
Phase 2Efficacy & side effects
7(43.8%)
Phase 3Large-scale testing
7(43.8%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

87.5%

7 of 8 finished

Non-Completion Rate

12.5%

1 ended early

Currently Active

8

trials recruiting

Total Trials

16

all time

Status Distribution
Active(8)
Completed(7)
Terminated(1)

Detailed Status

Completed7
Recruiting5
Active, not recruiting3
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
16
Active
8
Success Rate
87.5%
Most Advanced
Phase 3

Trials by Phase

Phase 12 (12.5%)
Phase 27 (43.8%)
Phase 37 (43.8%)

Trials by Status

active_not_recruiting319%
recruiting531%
terminated16%
completed744%

Recent Activity

Clinical Trials (16)

Showing 16 of 16 trials
NCT06500702Phase 2

A Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease

Recruiting
NCT07190196Phase 3

A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease

Recruiting
NCT07007962Phase 3

Study to Evaluate the Efficacy and Safety of Oral Rilzabrutinib in Adults With Immune Thrombocytopenia (ITP) Who Failed First-line Treatment

Recruiting
NCT06975865Phase 3

The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease

Recruiting
NCT07086976Phase 3

A Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Oral Rilzabrutinib Compared With Placebo in Participants 18 Years of Age and Older With Warm Autoimmune Hemolytic Anemia

Recruiting
NCT04562766Phase 3

Study to Evaluate Rilzabrutinib in Adults and Adolescents With Persistent or Chronic Immune Thrombocytopenia (ITP)

Active Not Recruiting
NCT03395210Phase 2

A Study of Rilzabrutinib in Adult Patients With Immune Thrombocytopenia (ITP)

Completed
NCT07216079Phase 3

Rilzabrutinib for the Adult Participants With Chronic ITP Who Have Completed Phase 3 Study in Japan

Active Not Recruiting
NCT04520451Phase 2

Open Label Two-Arm Study to Evaluate Rilzabrutinib in IgG4-Related Disease Participants

Completed
NCT05002777Phase 2

Efficacy, Safety and Pharmacokinetics of Rilzabrutinib in Patients With Warm Autoimmune Hemolytic Anemia (wAIHA)

Active Not Recruiting
NCT05107115Phase 2

Rilzabrutinib for the Treatment of Chronic Spontaneous Urticaria in Patients Who Remain Symptomatic Despite the Use of H1 Antihistamine

Completed
NCT05018806Phase 2

Proof of Concept Study of Rilzabrutinib in Adult Patients With Moderate-to-severe Atopic Dermatitis

Completed
NCT06444191Phase 1

Pharmacokinetics (PK) of Rilzabrutinib (PRN1008) in Healthy Japanese and Caucasian Subjects

Completed
NCT06444204Phase 1

A Study to Evaluate the Effect of Mild and Moderate Hepatic Impairment on the Single-Dose Pharmacokinetics of Rilzabrutinib (PRN1008)

Completed
NCT05104892Phase 2

Proof of Concept Study of Rilzabrutinib in Adult Participants With Moderate-to-severe Asthma

Completed
NCT03762265Phase 3

A Study of PRN1008 in Patients With Pemphigus

Terminated

All 16 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
16