Success Metrics

Clinical Success Rate
78.3%

Based on 18 completed trials

Completion Rate
78%(18/23)
Active Trials
21(44%)
Results Posted
89%(16 trials)
Terminated
5(10%)

Phase Distribution

Ph phase_2
30
63%
Ph phase_1
16
33%
Ph phase_3
1
2%

Phase Distribution

16

Early Stage

30

Mid Stage

1

Late Stage

Phase Distribution47 total trials
Phase 1Safety & dosage
16(34.0%)
Phase 2Efficacy & side effects
30(63.8%)
Phase 3Large-scale testing
1(2.1%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

75.0%

18 of 24 finished

Non-Completion Rate

25.0%

6 ended early

Currently Active

21

trials recruiting

Total Trials

48

all time

Status Distribution
Active(21)
Completed(18)
Terminated(6)
Other(3)

Detailed Status

Completed18
Active, not recruiting11
Recruiting10
Terminated5
unknown2
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
48
Active
21
Success Rate
78.3%
Most Advanced
Phase 3

Trials by Phase

Phase 116 (34.0%)
Phase 230 (63.8%)
Phase 31 (2.1%)

Trials by Status

completed1838%
active_not_recruiting1123%
recruiting1021%
terminated510%
unknown24%
withdrawn12%
suspended12%

Recent Activity

Clinical Trials (48)

Showing 20 of 48 trialsScroll for more
NCT06325683Phase 2

Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Suspended
NCT02465060Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Active Not Recruiting
NCT05987241Phase 2

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Recruiting
NCT03899155Phase 2

Pan Tumor Rollover Study

Recruiting
NCT06561386Phase 3

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

Recruiting
NCT06816927Phase 2

Trial of Glioblastoma Immunotherapy Advancement With Nivolumab and Relatlimab

Recruiting
NCT06029270Phase 2

Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer

Recruiting
NCT04080804Phase 2

Study of Safety and Tolerability of Nivolumab Treatment Alone or in Combination With Relatlimab or Ipilimumab in Head and Neck Cancer

Active Not Recruiting
NCT03743766Phase 2

Nivolumab, BMS-936558 in Combination With Relatlimab, BMS-986016 in Patients With Metastatic Melanoma Naïve to Prior Immunotherapy in the Metastatic Setting

Completed
NCT06683755Phase 1

Phase I/IIa Dose Finding Study of Triplet Regimen of Relatlimab Ipilimumab and NIvolumab in First Line Therapy of Metastatic Melanoma (TRINITY)

Recruiting
NCT05034536Phase 2

PD-1 Antibody Therapy + Infliximab for Metastatic Melanoma

Active Not Recruiting
NCT07504796Phase 2

ctDNA-guided Addition of Ipilimumab to Patients Receiving Nivolumab and Relatlimab

Recruiting
NCT05704647Phase 2

Phase II Study of Nivolumab in Combination With Relatlimab in Patients With Active Melanoma Brain Metastases

Recruiting
NCT06237920Phase 2

Stage II-IIIa Urothelial Cancer Randomizing Pre-operative Nivolumab With or Without Relatlimab

Active Not Recruiting
NCT05255601Phase 1

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of Relatlimab Plus Nivolumab in Pediatric and Young Adults With Hodgkin and Non-Hodgkin Lymphoma

Terminated
NCT04623775Phase 2

A Study of Relatlimab Plus Nivolumab in Combination With Chemotherapy vs. Nivolumab in Combination With Chemotherapy as First Line Treatment for Participants With Stage IV or Recurrent Non-small Cell Lung Cancer (NSCLC)

Completed
NCT04658147Phase 1

Feasibility and Efficacy of Perioperative Nivolumab With or Without Relatlimab for Patients With Potentially Resectable Hepatocellular Carcinoma (HCC)

Active Not Recruiting
NCT03610711Phase 1

REACTION (Radiation Enhanced Assessment of Combination Therapies in Immuno-ONcology) - Nivolumab or Nivolumab in Combination With Other Immuno-oncology (IO) Agents After Targeted Systemic Radiation in Patients With Advanced Esophagogastric Cancer

Active Not Recruiting
NCT03521830Phase 2

Nivolumab Alone or Plus Relatlimab or Ipilimumab for Patients With Locally-Advanced Unresectable or Metastatic Basal Cell Carcinoma

Recruiting
NCT05347212Phase 2

Phase II Trial of Immunotherapy in Patients With Carcinomas Arising From the Renal Medulla

Active Not Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
48