Success Metrics

Clinical Success Rate
91.8%

Based on 201 completed trials

Completion Rate
92%(201/219)
Active Trials
8(3%)
Results Posted
52%(104 trials)
Terminated
18(6%)

Phase Distribution

Ph phase_2
78
27%
Ph phase_4
63
21%
Ph phase_1
50
17%
Ph early_phase_1
1
0%
Ph not_applicable
20
7%
Ph phase_3
64
22%

Phase Distribution

51

Early Stage

78

Mid Stage

127

Late Stage

Phase Distribution276 total trials
Early Phase 1First-in-human
1(0.4%)
Phase 1Safety & dosage
50(18.1%)
Phase 2Efficacy & side effects
78(28.3%)
Phase 3Large-scale testing
64(23.2%)
Phase 4Post-market surveillance
63(22.8%)
N/ANon-phased studies
20(7.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

84.8%

201 of 237 finished

Non-Completion Rate

15.2%

36 ended early

Currently Active

8

trials recruiting

Total Trials

294

all time

Status Distribution
Active(8)
Completed(201)
Terminated(36)
Other(49)

Detailed Status

Completed201
unknown49
Withdrawn18
Terminated18
Active, not recruiting6
Recruiting2

Development Timeline

Analytics

Development Status

Total Trials
294
Active
8
Success Rate
91.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.4%)
Phase 150 (18.1%)
Phase 278 (28.3%)
Phase 364 (23.2%)
Phase 463 (22.8%)
N/A20 (7.2%)

Trials by Status

completed20168%
active_not_recruiting62%
withdrawn186%
recruiting21%
unknown4917%
terminated186%

Recent Activity

Clinical Trials (294)

Showing 20 of 294 trialsScroll for more
NCT06847542Phase 3

A Study of 36-Week Refill Exchanges of Port Delivery System (PDS) With Ranibizumab in nAMD

Recruiting
NCT06176352Phase 3

A Study to Evaluate the Efficacy and Safety of Faricimab in Patients With Choroidal Neovascularization Secondary to Pathologic Myopia

Active Not Recruiting
NCT04514653Phase 2

RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Neovascular Age-Related Macular Degeneration (nAMD)

Active Not Recruiting
NCT04657289Phase 3

A Study of the Efficacy, Safety, and Pharmacokinetics of a 36-Week Refill Regimen for the Port Delivery System With Ranibizumab in Patients With Neovascular Age-Related Macular Degeneration (Velodrome)

Active Not Recruiting
NCT04567303Phase 1

Study of Zifibancimig in Participants With Neovascular Age-related Macular Degeneration

Active Not Recruiting
NCT06957080Phase 2

A Study of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DME

Active Not Recruiting
NCT00527475Phase 2

Ranibizumab and Reduced Fluence PDT for AMD

Completed
NCT07249216Not Applicable

Identification of Molecular Signals in Vitreous Humor Associated With Suboptimal Response to Vascular Endothelial Growth Factor (VEGF) Inhibition in Neovascular Age-related Macular Degeneration (nAMD) Within a Clinical Trial Setting

Recruiting
NCT05151731Phase 2

A Study to Investigate Vamikibart (RO7200220) in Diabetic Macular Edema

Completed
NCT05151744Phase 2

A Study to Investigate Vamikibart (RO7200220) in Combination With Ranibizumab in Diabetic Macular Edema

Completed
NCT03832179Phase 4

Steroid vs. Anti-vascular Endothelial Growth Factor for Diabetic Macular Edema Prior to Phacoemulsification

Completed
NCT06571045Phase 2

A Study to Evaluate the Efficacy and Safety of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DME

Active Not Recruiting
NCT05576792

A 24-week Study Evaluating the Effectiveness and Safety of Lucentis® 0.2mg in Retinopathy of Prematurity Participants in China

Completed
NCT03844074Phase 3

A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)

Completed
NCT03834753Phase 3

A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)

Completed
NCT06190093Phase 3

A 3-month Study to Assess the Safety and Effectiveness of ONS-5010 in Subjects with Neovascular Age-related Macular Degeneration (AMD)

Completed
NCT06771271Phase 1

A Study to Investigate RO7200220 as Monotherapy and in Combination With Ranibizumab in Participants With Diabetic and Uveitic Macular Edema

Completed
NCT04740671Phase 3

A Phase 3 Study to Compare the Efficacy and Safety of HLX04-O with Ranibizumab in Subjects with WAMD

Completed
NCT02302079Phase 2

A Study to Evaluate ASP8232 in Reducing Central Retinal Thickness in Subjects With Diabetic Macular Edema (DME)

Completed
NCT01944839Phase 3

A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Lucentis® Compared to Lucentis® Monotherapy

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
294