Success Metrics

Clinical Success Rate
91.9%

Based on 203 completed trials

Completion Rate
92%(203/221)
Active Trials
8(3%)
Results Posted
53%(107 trials)
Terminated
18(6%)

Phase Distribution

Ph not_applicable
20
7%
Ph phase_4
64
22%
Ph phase_2
79
27%
Ph early_phase_1
1
0%
Ph phase_1
50
17%
Ph phase_3
64
22%

Phase Distribution

51

Early Stage

79

Mid Stage

128

Late Stage

Phase Distribution278 total trials
Early Phase 1First-in-human
1(0.4%)
Phase 1Safety & dosage
50(18.0%)
Phase 2Efficacy & side effects
79(28.4%)
Phase 3Large-scale testing
64(23.0%)
Phase 4Post-market surveillance
64(23.0%)
N/ANon-phased studies
20(7.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

84.9%

203 of 239 finished

Non-Completion Rate

15.1%

36 ended early

Currently Active

8

trials recruiting

Total Trials

297

all time

Status Distribution
Active(9)
Completed(203)
Terminated(36)
Other(49)

Detailed Status

Completed203
unknown49
Withdrawn18
Terminated18
Active, not recruiting5
Recruiting3

Development Timeline

Analytics

Development Status

Total Trials
297
Active
8
Success Rate
91.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.4%)
Phase 150 (18.0%)
Phase 279 (28.4%)
Phase 364 (23.0%)
Phase 464 (23.0%)
N/A20 (7.2%)

Trials by Status

withdrawn186%
enrolling_by_invitation10%
active_not_recruiting52%
completed20368%
recruiting31%
terminated186%
unknown4916%

Recent Activity

Clinical Trials (297)

Showing 20 of 297 trialsScroll for more
NCT05210803Phase 2

Long-Term Follow-Up Study of RGX-314 Administered in the Suprachoroidal Space for Participants With nAMD

Enrolling By Invitation
NCT03834753Phase 3

A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)

Completed
NCT04657289Phase 3

A Study of the Efficacy, Safety, and Pharmacokinetics of a 36-Week Refill Regimen for the Port Delivery System With Ranibizumab in Patients With Neovascular Age-Related Macular Degeneration (Velodrome)

Active Not Recruiting
NCT06176352Phase 3

A Study to Evaluate the Efficacy and Safety of Faricimab in Patients With Choroidal Neovascularization Secondary to Pathologic Myopia

Completed
NCT06190093Phase 3

A 3-month Study to Assess the Safety and Effectiveness of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)

Completed
NCT06847542Phase 3

A Study of 36-Week Refill Exchanges of Port Delivery System (PDS) With Ranibizumab in nAMD

Recruiting
NCT07701759

Incidence of Hypoxia During Intravitreal Anti-VEGF (Vascular Endothelial Growth Factor) Injections for Retinopathy of Prematurity (ROP) Under Topical Anesthesia

Recruiting
NCT07690800Phase 4

Outcomes of Intravitreal Ranibizumab Injection for Diabetic Vitreous Hemorrhage

Completed
NCT06957080Phase 2

A Study of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DME

Active Not Recruiting
NCT06571045Phase 2

A Study to Evaluate the Efficacy and Safety of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DME

Active Not Recruiting
NCT05151731Phase 2

A Study to Investigate Vamikibart (RO7200220) in Diabetic Macular Edema

Completed
NCT04567303Phase 1

Study of Zifibancimig in Participants With Neovascular Age-related Macular Degeneration

Active Not Recruiting
NCT04514653Phase 2

RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Neovascular Age-Related Macular Degeneration (nAMD)

Active Not Recruiting
NCT00527475Phase 2

Ranibizumab and Reduced Fluence PDT for AMD

Completed
NCT07249216Not Applicable

Identification of Molecular Signals in Vitreous Humor Associated With Suboptimal Response to Vascular Endothelial Growth Factor (VEGF) Inhibition in Neovascular Age-related Macular Degeneration (nAMD) Within a Clinical Trial Setting

Recruiting
NCT05151744Phase 2

A Study to Investigate Vamikibart (RO7200220) in Combination With Ranibizumab in Diabetic Macular Edema

Completed
NCT03832179Phase 4

Steroid vs. Anti-vascular Endothelial Growth Factor for Diabetic Macular Edema Prior to Phacoemulsification

Completed
NCT05576792

A 24-week Study Evaluating the Effectiveness and Safety of Lucentis® 0.2mg in Retinopathy of Prematurity Participants in China

Completed
NCT03844074Phase 3

A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)

Completed
NCT06771271Phase 1

A Study to Investigate RO7200220 as Monotherapy and in Combination With Ranibizumab in Participants With Diabetic and Uveitic Macular Edema

Completed

Drug Details

Intervention Type
DRUG
Total Trials
297