Success Metrics

Clinical Success Rate
91.5%

Based on 108 completed trials

Completion Rate
92%(108/118)
Active Trials
0(0%)
Results Posted
69%(75 trials)
Terminated
10(8%)

Phase Distribution

Ph phase_2
16
12%
Ph phase_4
37
28%
Ph not_applicable
19
14%
Ph phase_3
17
13%
Ph phase_1
29
22%
Ph early_phase_1
1
1%

Phase Distribution

30

Early Stage

16

Mid Stage

54

Late Stage

Phase Distribution119 total trials
Early Phase 1First-in-human
1(0.8%)
Phase 1Safety & dosage
29(24.4%)
Phase 2Efficacy & side effects
16(13.4%)
Phase 3Large-scale testing
17(14.3%)
Phase 4Post-market surveillance
37(31.1%)
N/ANon-phased studies
19(16.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

90.0%

108 of 120 finished

Non-Completion Rate

10.0%

12 ended early

Currently Active

0

trials recruiting

Total Trials

132

all time

Status Distribution
Completed(108)
Terminated(12)
Other(12)

Detailed Status

Completed108
unknown12
Terminated10
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
132
Active
0
Success Rate
91.5%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.8%)
Phase 129 (24.4%)
Phase 216 (13.4%)
Phase 317 (14.3%)
Phase 437 (31.1%)
N/A19 (16.0%)

Trials by Status

terminated108%
unknown129%
completed10882%
withdrawn22%

Recent Activity

Clinical Trials (132)

Showing 20 of 132 trialsScroll for more
NCT01453192Phase 3

Renal Transplantation and Raltegravir in HIV-Infected Patients

Completed
NCT00931463Phase 4

A Trial of 2 Options for Second Line Combination Antiretroviral Therapy Following Virological Failure of a Standard Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI)+2N(t)RTI First Line Regimen

Completed
NCT00042289

Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy

Completed
NCT03194165

Population Pharmacokinetics of Antiretroviral in Children

Completed
NCT03311945Phase 3

Simplification Study of HIV-1 Infected Patients With Virological Suppression Under the Combination of Lamivudine (150 mg BID) Plus Raltegravir (400 mg BID) Switching to Lamivudine (300 mg QD) Plus Raltegravir (1200 mg QD) : Roll-over Study of the RALAM

Completed
NCT01513122Phase 4

Bone and Body Comp: A Sub Study of the SECOND-LINE Study

Completed
NCT03029689Phase 3

Clinical Trial to Evaluate the Effect of Raltegravir Intensification (1.200 mg QD) on the Gut Microbiota of Chronically HIV-1 Infected Subject Over Time: THE RAGTIME STUDY

Completed
NCT03333083Phase 3

Study With Dual Therapy Including Lamivudine (300 mg QD) Plus Raltegravir (1200 mg QD) in Virologically Suppressed HIV-1 Infected Patients Experiencing Inconvenience, Toxicity, Negative Impact on Co-morbidities or Risk of Drug-drug Interactions With Their Current Regimen

Terminated
NCT01854762Phase 2

Antiretroviral Regimens Containing Raltegravir for Prophylaxis of Mother-to-child-transmission of HIV Infection

Terminated
NCT03954327Phase 2

Combination Antiretroviral Therapy (cART) for PBC

Completed
NCT02336074Phase 2

Research In Viral Eradication of HIV Reservoirs

Completed
NCT01867320Early Phase 1

Raltegravir for HAM/TSP

Completed
NCT05751031

Pregnancy and Neonatal Outcomes Following Antenatal Exposure to Raltegravir: a Pooled Analysis From the European Pregnancy and Paediatric Infections Cohort Collaboration (EPPICC)

Unknown
NCT01231516Phase 3

A Study of GSK1349572 Versus Raltegravir (RAL) With Investigator Selected Background Regimen in Antiretroviral-Experienced, Integrase Inhibitor-Naive Adults

Completed
NCT01828073

Evaluating the Safety and Pharmacokinetics of Raltegravir in Infants

Completed
NCT01751568Phase 1

Safety, Tolerance and Pharmacokinetics of Raltegravir-Containing Antiretroviral Therapy in Infants, Children Infected With HIV and TB

Completed
NCT01780831Phase 1

Safety and Pharmacokinetics of Raltegravir in HIV-1-Exposed Newborn Infants at Risk of Acquiring HIV-1 Infection

Completed
NCT00537394Phase 3

Optimizing Treatment for Treatment-Experienced, HIV-Infected People

Completed
NCT00660972Phase 1

Study of Viral Load Decay Rates in HIV Infected Participants Starting Treatment With Raltegravir (RAL) and Emtricitabine/Tenofovir Disoproxil Fumarate (TDF)

Completed
NCT03374358Phase 4

Effect on Liver Fat and Metabolic Parameters When Switching a Protease Inhibitor or Efavirenz to Raltegravir

Completed

Drug Details

Intervention Type
DRUG
Total Trials
132