Success Metrics

Clinical Success Rate
87.5%

Based on 14 completed trials

Completion Rate
88%(14/16)
Active Trials
0(0%)
Results Posted
43%(6 trials)
Terminated
2(8%)

Phase Distribution

Ph phase_1
5
19%
Ph phase_2
9
35%
Ph phase_3
5
19%
Ph phase_4
2
8%
Ph not_applicable
4
15%

Phase Distribution

5

Early Stage

9

Mid Stage

7

Late Stage

Phase Distribution25 total trials
Phase 1Safety & dosage
5(20.0%)
Phase 2Efficacy & side effects
9(36.0%)
Phase 3Large-scale testing
5(20.0%)
Phase 4Post-market surveillance
2(8.0%)
N/ANon-phased studies
4(16.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

60.9%

14 of 23 finished

Non-Completion Rate

39.1%

9 ended early

Currently Active

0

trials recruiting

Total Trials

26

all time

Status Distribution
Completed(14)
Terminated(9)
Other(3)

Detailed Status

Completed14
Withdrawn7
unknown3
Terminated2

Development Timeline

Analytics

Development Status

Total Trials
26
Active
0
Success Rate
87.5%
Most Advanced
Phase 4

Trials by Phase

Phase 15 (20.0%)
Phase 29 (36.0%)
Phase 35 (20.0%)
Phase 42 (8.0%)
N/A4 (16.0%)

Trials by Status

withdrawn727%
completed1454%
unknown312%
terminated28%

Recent Activity

Clinical Trials (26)

Showing 20 of 26 trialsScroll for more
NCT02563327Phase 3

Pharmacokinetic and Pharmacodynamic Study of High-Dose Rifapentine and Moxifloxacin for Treatment of Tuberculosis

Completed
NCT03510468Phase 1

Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy Volunteers (YODA)

Completed
NCT06244121Not Applicable

Effect of Pyridoxine as Add-on Therapy in OCD Patients

Unknown
NCT03287778Not Applicable

Randomized Controlled Trial of Pyridoxine for Tardive Dyskinesia

Completed
NCT05024422Not Applicable

Lactation Inhibition, the Efficiency of Vitamin B6 Versus Cabergoline

Completed
NCT01730313Phase 2

Treatment of Nodding Syndrome - A Randomized Blinded Placebo-Controlled Crossover Trial of Oral Pyridoxine and Conventional Anti-Epileptic Therapy, in Northern Uganda - 2012

Withdrawn
NCT02771249Phase 1

Impact of Once-Weekly Rifapentine and Isoniazid on the Steady State Pharmacokinetics of Dolutegravir and Darunavir Boosted With Cobicistat in Healthy Volunteers

Completed
NCT05008354Phase 4

Effect of Pyridoxine on Behavioral Adverse Events of Levetiracetam

Completed
NCT01983969Phase 1

Aza-SAHA-GBM With AutoSCT for Refractory Lymphoma

Completed
NCT03790345Phase 2

Vitamin B6 and B12 in the Treatment of Movement Disorders Induced by Antipsychotics

Unknown
NCT02589145Phase 1

Lenalidomide Combined With Vorinostat/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Diffuse Large B-Cell Lymphoma of the ABC Subtype

Terminated
NCT01601626Phase 2

Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in Persons With HIV

Terminated
NCT02773147Phase 2

Effect of Vitamin B on Plasma Neurofilament Light Protein (NFL) in HIV-infected Individuals With Increased Plasma Homocysteine

Unknown
NCT01785186Phase 2

Evaluation of SQ109, High-dose Rifampicin, and Moxifloxacin in Adults With Smear-positive Pulmonary TB in a MAMS Design

Completed
NCT02961816Phase 2

Panobinostat Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant for Patients With Refractory/Relapsed Lymphoma

Withdrawn
NCT02701673Phase 1

Belinostat Combined With Azacitidine/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Refractory or Relapsed Lymphoma

Withdrawn
NCT00004495Not Applicable

Randomized Study of Folic Acid Therapy for Hyperhomocysteinemia in Patients With End Stage Renal Disease Receiving Hemodialysis

Completed
NCT01795170

Neurodevelopmental Outcome of Early Dietary Lysine Restriction in Pyridoxine Dependent Epilepsy Patients

Withdrawn
NCT02114502Phase 2

Carfilzomib/SAHA Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant in Myeloma

Withdrawn
NCT00446147Phase 3

Study of Pyridoxine for Hand-Foot Syndrome

Completed

Drug Details

Intervention Type
DIETARY SUPPLEMENT
Total Trials
26